ENSG00000131089

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000498761 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding retained_intron 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 0.6641301 1.9923903 0.0000000 0.4850329 0.0000000 -7.64557937 0.03110000 0.093300 0.000000 -0.093300 0.005904849 0.005904849   FALSE
ENST00000624210 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding protein_coding 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 0.8730539 1.2163983 0.7513001 0.8560968 0.7513001 -0.68789047 0.07828333 0.083100 0.071725 -0.011375 0.860579959 0.005904849 FALSE TRUE
ENST00000624538 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding protein_coding 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 1.7130302 2.3717666 0.0000000 0.9508234 0.0000000 -7.89588826 0.12540000 0.108525 0.000000 -0.108525 0.097156589 0.005904849 FALSE TRUE
ENST00000624783 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding protein_coding_CDS_not_defined 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 2.5451264 3.8907521 2.1205066 1.4120498 1.2283424 -0.87255582 0.12516667 0.169075 0.104275 -0.064800 0.834149181 0.005904849 FALSE TRUE
ENST00000624843 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding protein_coding 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 1.4329490 0.1953045 3.2301809 0.1953045 0.3092259 3.98023732 0.10299167 0.010375 0.230700 0.220325 0.011580570 0.005904849 FALSE TRUE
ENST00000636539 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding protein_coding_CDS_not_defined 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 7.5944190 11.1511166 11.6321403 11.1511166 11.6321403 0.06087494 0.12830833 0.184525 0.200400 0.015875 0.994111054 0.005904849   FALSE
ENST00000637855 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding nonsense_mediated_decay 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 0.7400908 1.2832101 0.1081893 0.3018130 0.1081893 -3.45178495 0.05127500 0.063150 0.010325 -0.052825 0.345218624 0.005904849 TRUE TRUE
ENST00000671907 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding protein_coding 20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 0.4288388 0.0000000 1.2865164 0.0000000 0.8028637 7.01849662 0.02410000 0.000000 0.072300 0.072300 0.370464297 0.005904849 FALSE TRUE
MSTRG.30048.6 ENSG00000131089 No_inf pgKDN_inf ARHGEF9 protein_coding   20.68396 28.21515 22.65767 10.82886 11.82108 -0.3163451 0.8709365 1.2144921 1.1557088 0.4941526 0.4507784 -0.07097607 0.06111667 0.069550 0.098550 0.029000 1.000000000 0.005904849 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131089 E001 0.1268540 0.0124502650 0.894219970   X 63634967 63634970 4 - 0.000 0.077 9.433
ENSG00000131089 E002 0.1268540 0.0124502650 0.894219970   X 63634971 63634983 13 - 0.000 0.077 11.981
ENSG00000131089 E003 0.2444846 0.0162598451 0.715511757   X 63634984 63635002 19 - 0.117 0.077 -0.664
ENSG00000131089 E004 0.2444846 0.0162598451 0.715511757   X 63635003 63635014 12 - 0.117 0.077 -0.664
ENSG00000131089 E005 0.3709916 0.0165081895 0.931045807   X 63635015 63635070 56 - 0.117 0.143 0.336
ENSG00000131089 E006 0.6145027 0.0159303080 0.945110498 0.98495883 X 63635071 63635160 90 - 0.208 0.200 -0.079
ENSG00000131089 E007 3.1087622 0.0055103543 0.276707642 0.57013830 X 63635161 63635298 138 - 0.499 0.653 0.699
ENSG00000131089 E008 4.7240214 0.0031106074 0.220652275 0.50760337 X 63635299 63635408 110 - 0.642 0.796 0.632
ENSG00000131089 E009 30.4218618 0.0004631885 0.521651431 0.77544645 X 63635409 63636330 922 - 1.458 1.496 0.130
ENSG00000131089 E010 5.4772772 0.0026981882 0.119413044 0.36524829 X 63636331 63636533 203 - 0.672 0.859 0.751
ENSG00000131089 E011 12.1682340 0.0013897249 0.156647027 0.42300109 X 63636534 63636917 384 - 1.023 1.147 0.448
ENSG00000131089 E012 11.9737111 0.0025364186 0.005340314 0.05196184 X 63636918 63637308 391 - 0.924 1.176 0.921
ENSG00000131089 E013 8.7561039 0.0017616204 0.868520569 0.95483711 X 63637309 63637689 381 - 0.983 0.971 -0.045
ENSG00000131089 E014 2.2389530 0.0076949755 0.344425699 0.63571175 X 63637690 63637745 56 - 0.405 0.548 0.715
ENSG00000131089 E015 1.4961805 0.0091458541 0.326897480 0.61932305 X 63637746 63637839 94 - 0.284 0.439 0.921
ENSG00000131089 E016 0.0000000       X 63637840 63637867 28 -      
ENSG00000131089 E017 0.1176306 0.0117794784 0.329912964   X 63637868 63637884 17 - 0.117 0.000 -13.734
ENSG00000131089 E018 0.2362687 0.0156811855 0.119190387   X 63637885 63637905 21 - 0.208 0.000 -14.606
ENSG00000131089 E019 0.6085502 0.0162674491 0.336065323 0.62795687 X 63637906 63637981 76 - 0.284 0.143 -1.249
ENSG00000131089 E020 0.4994178 0.0193832871 0.596733173   X 63637982 63637984 3 - 0.117 0.200 0.921
ENSG00000131089 E021 0.6265541 0.1268148098 0.440214453 0.71597739 X 63637985 63638007 23 - 0.117 0.250 1.336
ENSG00000131089 E022 3.2037029 0.0113645541 0.692337450 0.87411695 X 63638008 63638026 19 - 0.642 0.593 -0.216
ENSG00000131089 E023 3.6952905 0.0050794879 0.589132424 0.81780733 X 63638027 63638049 23 - 0.699 0.634 -0.277
ENSG00000131089 E024 12.2574553 0.0011731661 0.516038943 0.77182597 X 63638050 63638209 160 - 1.071 1.129 0.207
ENSG00000131089 E025 0.0000000       X 63638553 63638662 110 -      
ENSG00000131089 E026 0.1272623 0.0123780616 0.894270563   X 63639415 63639445 31 - 0.000 0.077 11.981
ENSG00000131089 E027 0.1272623 0.0123780616 0.894270563   X 63639446 63639523 78 - 0.000 0.077 11.981
ENSG00000131089 E028 0.0000000       X 63639524 63639555 32 -      
ENSG00000131089 E029 0.0000000       X 63639556 63639619 64 -      
ENSG00000131089 E030 2.6574277 0.0055237766 0.005279511 0.05162886 X 63639620 63642046 2427 - 0.750 0.373 -1.763
ENSG00000131089 E031 0.2447669 0.0162327533 0.714383239   X 63642047 63642910 864 - 0.117 0.077 -0.664
ENSG00000131089 E032 6.5509591 0.0067417592 0.697256463 0.87642934 X 63643980 63643995 16 - 0.836 0.881 0.176
ENSG00000131089 E033 10.0714635 0.0019358488 0.220899506 0.50787586 X 63643996 63644048 53 - 1.093 0.989 -0.381
ENSG00000131089 E034 0.5077596 0.0150790107 0.122460857 0.37028670 X 63644049 63644266 218 - 0.000 0.250 13.724
ENSG00000131089 E035 15.5178753 0.0017223360 0.411445410 0.69311907 X 63655494 63655615 122 - 1.239 1.182 -0.202
ENSG00000131089 E036 13.8290324 0.0010497400 0.860713671 0.95173878 X 63655616 63655737 122 - 1.163 1.153 -0.036
ENSG00000131089 E037 4.4414349 0.0040490335 0.957915760 0.98990594 X 63655738 63656509 772 - 0.725 0.722 -0.012
ENSG00000131089 E038 6.1393048 0.0494278884 0.028500751 0.15808512 X 63656510 63657388 879 - 0.611 0.934 1.300
ENSG00000131089 E039 3.3425223 0.0102655526 0.585025332 0.81561311 X 63657389 63657904 516 - 0.577 0.653 0.336
ENSG00000131089 E040 0.8724545 0.0695730365 0.604883246 0.82777885 X 63657905 63658064 160 - 0.209 0.295 0.658
ENSG00000131089 E041 11.0026304 0.0013740107 0.785047251 0.91717419 X 63665886 63666017 132 - 1.048 1.075 0.099
ENSG00000131089 E042 8.2653136 0.0078575688 0.774950722 0.91353804 X 63674038 63674167 130 - 0.969 0.943 -0.097
ENSG00000131089 E043 12.2107479 0.0011390542 0.693591708 0.87481993 X 63678340 63678495 156 - 1.125 1.096 -0.103
ENSG00000131089 E044 5.1587727 0.0026872133 0.375150019 0.66272191 X 63678496 63678503 8 - 0.836 0.738 -0.388
ENSG00000131089 E045 9.2595092 0.0016445161 0.972718809 0.99491032 X 63678504 63678572 69 - 0.997 0.998 0.002
ENSG00000131089 E046 9.8905356 0.0019390960 0.859141755 0.95099633 X 63697125 63697220 96 - 1.010 1.030 0.073
ENSG00000131089 E047 7.0328339 0.0020361043 0.774094475 0.91318460 X 63697221 63697275 55 - 0.908 0.881 -0.100
ENSG00000131089 E048 6.6192914 0.0024383831 0.151544725 0.41492321 X 63697276 63697304 29 - 0.955 0.809 -0.557
ENSG00000131089 E049 0.0000000       X 63701490 63701642 153 -      
ENSG00000131089 E050 0.7353133 0.0155397527 0.570416512 0.80698725 X 63703170 63703284 115 - 0.284 0.200 -0.664
ENSG00000131089 E051 4.6433326 0.0030462078 0.079501759 0.28921064 X 63706258 63706262 5 - 0.855 0.653 -0.816
ENSG00000131089 E052 11.7822442 0.0012152230 0.092379732 0.31561594 X 63706263 63706449 187 - 1.172 1.038 -0.483
ENSG00000131089 E053 0.0000000       X 63707411 63707434 24 -      
ENSG00000131089 E054 0.0000000       X 63709136 63709174 39 -      
ENSG00000131089 E055 0.0000000       X 63712907 63713112 206 -      
ENSG00000131089 E056 0.0000000       X 63715988 63716119 132 -      
ENSG00000131089 E057 0.1265070 0.0123046052 0.894303824   X 63719674 63719856 183 - 0.000 0.077 11.981
ENSG00000131089 E058 0.3808443 0.0397362036 0.234493937   X 63722762 63722897 136 - 0.000 0.200 13.348
ENSG00000131089 E059 9.2756934 0.0015457800 0.836474167 0.94139344 X 63724532 63724711 180 - 0.983 1.006 0.083
ENSG00000131089 E060 0.0000000       X 63724796 63724846 51 -      
ENSG00000131089 E061 0.0000000       X 63724847 63724975 129 -      
ENSG00000131089 E062 0.0000000       X 63725683 63725735 53 -      
ENSG00000131089 E063 0.0000000       X 63726646 63726693 48 -      
ENSG00000131089 E064 1.3624315 0.0444423479 0.898336502 0.96660111 X 63727191 63727419 229 - 0.349 0.373 0.144
ENSG00000131089 E065 0.7624406 0.0156161183 0.038676813 0.19025302 X 63727521 63727608 88 - 0.000 0.336 14.196
ENSG00000131089 E066 0.6093706 0.0147604581 0.335080551 0.62688571 X 63730476 63730520 45 - 0.284 0.143 -1.249
ENSG00000131089 E067 1.3711815 0.0097740999 0.437193484 0.71352842 X 63732006 63732310 305 - 0.284 0.408 0.751
ENSG00000131089 E068 0.1186381 0.0117628629 0.330063138   X 63736990 63737118 129 - 0.117 0.000 -13.734
ENSG00000131089 E069 0.0000000       X 63737119 63737280 162 -      
ENSG00000131089 E070 0.1271363 0.0122813440 0.894368229   X 63743369 63743446 78 - 0.000 0.077 11.982
ENSG00000131089 E071 0.1265070 0.0123046052 0.894303824   X 63754284 63754303 20 - 0.000 0.077 11.981
ENSG00000131089 E072 0.3622142 0.0164448299 0.333541433   X 63754304 63754307 4 - 0.208 0.077 -1.664
ENSG00000131089 E073 0.4809173 0.0299947069 0.146607237   X 63754308 63754314 7 - 0.284 0.077 -2.249
ENSG00000131089 E074 7.8681825 0.0018272817 0.266298589 0.55976714 X 63754315 63754484 170 - 0.997 0.892 -0.392
ENSG00000131089 E075 8.1140230 0.0018023906 0.365988522 0.65454235 X 63754485 63754676 192 - 0.997 0.914 -0.312
ENSG00000131089 E076 5.9074030 0.0132646403 0.484998129 0.74887937 X 63754677 63754920 244 - 0.873 0.796 -0.301
ENSG00000131089 E077 4.8033570 0.0671953700 0.603821063 0.82720310 X 63754921 63755018 98 - 0.795 0.722 -0.293
ENSG00000131089 E078 3.4580748 0.0042672036 0.931042681 0.97989767 X 63755019 63755143 125 - 0.642 0.634 -0.036
ENSG00000131089 E079 0.0000000       X 63755158 63755207 50 -      
ENSG00000131089 E080 0.0000000       X 63755208 63755335 128 -      
ENSG00000131089 E081 0.0000000       X 63755834 63755910 77 -      
ENSG00000131089 E082 0.1187032 0.0118742874 0.329870868   X 63785116 63785558 443 - 0.117 0.000 -13.733
ENSG00000131089 E083 0.0000000       X 63795516 63795576 61 -      
ENSG00000131089 E084 0.0000000       X 63809203 63809274 72 -      

Help

Please Click HERE to learn more details about the results from DEXseq.