ENSG00000131165

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397901 ENSG00000131165 No_inf pgKDN_inf CHMP1A protein_coding protein_coding 36.61719 37.06146 36.3669 0.4509412 0.9625023 -0.02728648 30.260631 28.178360 33.1745543 0.6379626 0.9916027 0.2354123 0.82701667 0.760800 0.91250 0.151700 0.004163738 0.004163738 FALSE TRUE
ENST00000551981 ENSG00000131165 No_inf pgKDN_inf CHMP1A protein_coding retained_intron 36.61719 37.06146 36.3669 0.4509412 0.9625023 -0.02728648 2.806547 3.425859 1.8682095 0.2598193 0.5662274 -0.8713128 0.07647500 0.092425 0.05105 -0.041375 0.594138724 0.004163738 TRUE TRUE
ENST00000676275 ENSG00000131165 No_inf pgKDN_inf CHMP1A protein_coding protein_coding_CDS_not_defined 36.61719 37.06146 36.3669 0.4509412 0.9625023 -0.02728648 1.205294 3.310972 0.3049116 0.4337077 0.1334420 -3.3985867 0.03251667 0.089300 0.00825 -0.081050 0.005419205 0.004163738 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131165 E001 5.5848521 0.0038092114 1.390523e-13 2.037948e-11 16 89640816 89641475 660 - 0.000 1.059 15.708
ENSG00000131165 E002 0.2541163 0.0159855826 2.715787e-01   16 89644237 89644434 198 - 0.000 0.169 13.983
ENSG00000131165 E003 3.3348730 0.0993461411 5.774410e-01 8.111817e-01 16 89644435 89644451 17 - 0.577 0.681 0.454
ENSG00000131165 E004 3.5800832 0.0879089920 5.812544e-01 8.133955e-01 16 89644452 89644455 4 - 0.605 0.702 0.416
ENSG00000131165 E005 4.6753146 0.0096323645 7.036244e-01 8.794530e-01 16 89644456 89644470 15 - 0.723 0.777 0.219
ENSG00000131165 E006 5.1653564 0.0030650358 7.275893e-01 8.913122e-01 16 89644471 89644478 8 - 0.763 0.811 0.190
ENSG00000131165 E007 5.2918634 0.0028362651 6.242221e-01 8.383793e-01 16 89644479 89644482 4 - 0.763 0.826 0.251
ENSG00000131165 E008 6.2739884 0.0024762688 6.861917e-01 8.703552e-01 16 89644483 89644502 20 - 0.832 0.884 0.198
ENSG00000131165 E009 34.0494255 0.0004310505 3.387231e-01 6.303462e-01 16 89644503 89644694 192 - 1.512 1.570 0.197
ENSG00000131165 E010 22.3313238 0.0006365819 8.487114e-01 9.463831e-01 16 89644695 89644769 75 - 1.356 1.377 0.073
ENSG00000131165 E011 22.7063982 0.0006653183 7.992048e-01 9.246677e-01 16 89644770 89644836 67 - 1.361 1.385 0.086
ENSG00000131165 E012 65.9671658 0.0036509110 4.640239e-02 2.113560e-01 16 89644837 89645120 284 - 1.773 1.866 0.315
ENSG00000131165 E013 46.4285259 0.0010341504 6.647833e-01 8.606389e-01 16 89645121 89645270 150 - 1.680 1.671 -0.032
ENSG00000131165 E014 134.2836568 0.0001625838 9.395841e-01 9.828133e-01 16 89645271 89645835 565 - 2.124 2.136 0.038
ENSG00000131165 E015 25.5563286 0.0006336800 3.467159e-01 6.373688e-01 16 89645836 89645888 53 - 1.447 1.402 -0.155
ENSG00000131165 E016 40.7847968 0.0005567408 3.689248e-02 1.849562e-01 16 89645889 89646087 199 - 1.664 1.578 -0.293
ENSG00000131165 E017 44.8686614 0.0003139656 8.688175e-02 3.055278e-01 16 89646527 89646714 188 - 1.694 1.629 -0.219
ENSG00000131165 E018 1.8388546 0.0119813121 9.207090e-01 9.752146e-01 16 89646715 89646733 19 - 0.442 0.463 0.107
ENSG00000131165 E019 4.5648977 0.0461465478 2.815008e-01 5.749191e-01 16 89646734 89646954 221 - 0.656 0.811 0.631
ENSG00000131165 E020 0.7436851 0.0140546519 4.724665e-01 7.397148e-01 16 89646955 89647034 80 - 0.177 0.290 0.914
ENSG00000131165 E021 0.3707734 0.0163894824 6.354125e-01   16 89647035 89647043 9 - 0.098 0.169 0.914
ENSG00000131165 E022 1.6141282 0.0082130603 2.131920e-01 4.984116e-01 16 89647044 89647121 78 - 0.303 0.497 1.084
ENSG00000131165 E023 3.0046992 0.0051413659 6.439047e-03 5.938801e-02 16 89647122 89647202 81 - 0.354 0.742 1.840
ENSG00000131165 E024 35.0126539 0.0041580642 3.381765e-01 6.300108e-01 16 89647203 89647331 129 - 1.578 1.535 -0.146
ENSG00000131165 E025 2.1123786 0.0516494132 1.620248e-01 4.303692e-01 16 89647332 89648478 1147 - 0.354 0.586 1.177
ENSG00000131165 E026 1.7512058 0.0079537162 4.207798e-02 1.996012e-01 16 89648479 89648997 519 - 0.245 0.558 1.789
ENSG00000131165 E027 0.2533610 0.0158997795 2.715482e-01   16 89648998 89649041 44 - 0.000 0.169 13.984
ENSG00000131165 E028 0.2545247 0.2356737352 3.243045e-01   16 89649179 89649350 172 - 0.000 0.169 13.392
ENSG00000131165 E029 16.6864902 0.0030638957 8.972302e-01 9.661308e-01 16 89649351 89649377 27 - 1.247 1.246 -0.001
ENSG00000131165 E030 24.2523596 0.0005498929 5.622001e-01 8.021238e-01 16 89649378 89649442 65 - 1.414 1.390 -0.086
ENSG00000131165 E031 20.3131954 0.0006949412 4.940283e-01 7.557344e-01 16 89649443 89649497 55 - 1.346 1.311 -0.120
ENSG00000131165 E032 0.1268540 0.0122600949 5.835148e-01   16 89649498 89649520 23 - 0.000 0.093 13.044
ENSG00000131165 E033 0.0000000       16 89649521 89649552 32 -      
ENSG00000131165 E034 0.0000000       16 89649553 89649593 41 -      
ENSG00000131165 E035 0.7516790 0.0137619397 1.132217e-01 3.539179e-01 16 89651262 89651343 82 - 0.098 0.340 2.236
ENSG00000131165 E036 18.1988597 0.0011385375 1.632402e-01 4.319171e-01 16 89651569 89651646 78 - 1.326 1.240 -0.299
ENSG00000131165 E037 0.0000000       16 89651647 89651669 23 -      
ENSG00000131165 E038 0.2543986 0.0159913932 2.715762e-01   16 89653799 89653903 105 - 0.000 0.169 13.983
ENSG00000131165 E039 6.8051241 0.0021598495 5.770298e-02 2.403578e-01 16 89653904 89653923 20 - 0.981 0.794 -0.714
ENSG00000131165 E040 0.2530140 0.2446026110 3.265293e-01   16 89653924 89654020 97 - 0.000 0.169 13.379
ENSG00000131165 E041 0.0000000       16 89654338 89654613 276 -      
ENSG00000131165 E042 0.2438580 0.0160530600 9.494816e-01   16 89656633 89656734 102 - 0.098 0.093 -0.086
ENSG00000131165 E043 1.1040089 0.0120167708 8.341194e-01 9.403130e-01 16 89656735 89657581 847 - 0.303 0.340 0.236
ENSG00000131165 E044 12.3586339 0.0235903306 6.491789e-03 5.971826e-02 16 89657582 89657738 157 - 1.247 0.980 -0.960

Help

Please Click HERE to learn more details about the results from DEXseq.