ENSG00000131196

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000253506 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 2.3491706 1.584922 3.6738987 1.0854922 0.8951072 1.2077479 0.09262500 0.090400 0.131775 0.041375 0.69455980 0.01004025 FALSE TRUE
ENST00000318065 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 3.2905562 1.867321 3.5385316 0.7898709 0.5512780 0.9185464 0.12185833 0.103650 0.125425 0.021775 0.85070247 0.01004025 FALSE TRUE
ENST00000427363 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 1.5757467 0.000000 2.9607740 0.0000000 1.1104949 8.2146950 0.05145833 0.000000 0.102525 0.102525 0.05559991 0.01004025 FALSE TRUE
ENST00000542384 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 6.0973345 2.841980 8.7230403 1.7063772 0.4328726 1.6145200 0.22802500 0.159825 0.311325 0.151500 0.50474435 0.01004025 FALSE TRUE
ENST00000545796 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 1.8701428 3.283968 0.9894594 1.2047693 0.4783030 -1.7206067 0.08680000 0.182100 0.036450 -0.145650 0.52689994 0.01004025 FALSE TRUE
ENST00000586434 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 2.2932594 4.389915 0.0000000 1.6054158 0.0000000 -8.7813319 0.10579167 0.248300 0.000000 -0.248300 0.01004025 0.01004025 FALSE TRUE
ENST00000590313 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding nonsense_mediated_decay 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 0.3271947 0.981584 0.0000000 0.9815840 0.0000000 -6.6316630 0.01907500 0.057225 0.000000 -0.057225 0.83059172 0.01004025 FALSE TRUE
ENST00000591814 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 5.9343216 1.350243 6.6239590 0.7826005 0.4649171 2.2860061 0.20463333 0.075975 0.238275 0.162300 0.32144609 0.01004025 FALSE TRUE
ENST00000592223 ENSG00000131196 No_inf pgKDN_inf NFATC1 protein_coding protein_coding 26.24684 17.75604 28.05497 0.3106147 0.9033796 0.6596487 0.4615454 1.384636 0.0000000 0.8267021 0.0000000 -7.1237451 0.02613333 0.078400 0.000000 -0.078400 0.41505064 0.01004025 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131196 E001 0.3533378 0.0158402695 2.192022e-01   18 79394249 79394299 51 + 0.200 0.000 -10.423
ENSG00000131196 E002 0.2442663 0.0165709518 7.330415e-01   18 79395856 79395929 74 + 0.077 0.117 0.662
ENSG00000131196 E003 1.1908597 0.0109022295 4.025231e-02 1.945312e-01 18 79395930 79395943 14 + 0.440 0.117 -2.508
ENSG00000131196 E004 8.7034137 0.0169375699 5.075265e-05 1.347756e-03 18 79395944 79396130 187 + 1.116 0.642 -1.833
ENSG00000131196 E005 7.9769916 0.0017033202 7.537330e-07 3.623158e-05 18 79396131 79396224 94 + 1.096 0.539 -2.221
ENSG00000131196 E006 11.1315322 0.0013833260 1.382688e-05 4.525116e-04 18 79396225 79396351 127 + 1.198 0.795 -1.499
ENSG00000131196 E007 0.1170040 0.0117401867 8.524051e-01   18 79399616 79399655 40 + 0.077 0.000 -11.148
ENSG00000131196 E008 1.7061698 0.0866612222 8.034591e-01 9.269322e-01 18 79400274 79400321 48 + 0.408 0.454 0.246
ENSG00000131196 E009 2.0588159 0.0070833107 7.408789e-01 8.971486e-01 18 79400322 79400330 9 + 0.497 0.454 -0.213
ENSG00000131196 E010 2.0588159 0.0070833107 7.408789e-01 8.971486e-01 18 79400331 79400332 2 + 0.497 0.454 -0.213
ENSG00000131196 E011 2.0588159 0.0070833107 7.408789e-01 8.971486e-01 18 79400333 79400335 3 + 0.497 0.454 -0.213
ENSG00000131196 E012 3.9100098 0.0047654120 3.882967e-01 6.741881e-01 18 79400336 79400391 56 + 0.634 0.750 0.481
ENSG00000131196 E013 4.9093829 0.0028959593 9.321719e-02 3.173727e-01 18 79400392 79400479 88 + 0.672 0.873 0.806
ENSG00000131196 E014 134.0454684 0.0001982096 2.634249e-10 2.488189e-08 18 79410403 79411501 1099 + 2.176 2.030 -0.487
ENSG00000131196 E015 34.6794387 0.0005920745 5.249054e-01 7.778371e-01 18 79433579 79433738 160 + 1.554 1.531 -0.081
ENSG00000131196 E016 0.1170040 0.0117401867 8.524051e-01   18 79448270 79448401 132 + 0.077 0.000 -11.148
ENSG00000131196 E017 0.0000000       18 79448572 79448781 210 +      
ENSG00000131196 E018 43.1097321 0.0003550822 1.266899e-01 3.772994e-01 18 79448782 79448984 203 + 1.660 1.600 -0.207
ENSG00000131196 E019 27.4538326 0.0006198920 8.209723e-01 9.350145e-01 18 79450954 79451041 88 + 1.448 1.444 -0.014
ENSG00000131196 E020 19.4691539 0.0070332817 6.305354e-01 8.414996e-01 18 79451042 79451078 37 + 1.285 1.329 0.151
ENSG00000131196 E021 21.2965078 0.0076450920 5.346977e-01 7.846112e-01 18 79451079 79451126 48 + 1.319 1.371 0.179
ENSG00000131196 E022 22.6324508 0.0006575614 1.558394e-01 4.218975e-01 18 79451676 79451816 141 + 1.397 1.316 -0.281
ENSG00000131196 E023 0.1176306 0.0117860842 8.524036e-01   18 79451817 79452131 315 + 0.077 0.000 -11.147
ENSG00000131196 E024 0.0000000       18 79461311 79461366 56 +      
ENSG00000131196 E025 29.0456726 0.0005509995 9.745761e-01 9.954114e-01 18 79467450 79467582 133 + 1.466 1.476 0.036
ENSG00000131196 E026 45.1915818 0.0004675614 7.463740e-02 2.785661e-01 18 79467583 79470014 2432 + 1.684 1.613 -0.241
ENSG00000131196 E027 14.3678327 0.0015507282 8.006878e-04 1.261592e-02 18 79486248 79486630 383 + 1.054 1.316 0.934
ENSG00000131196 E028 8.2190288 0.0018498705 3.248966e-02 1.707892e-01 18 79486631 79486937 307 + 0.859 1.071 0.791
ENSG00000131196 E029 0.1271363 0.0124380850 3.414766e-01   18 79493396 79493823 428 + 0.000 0.117 11.103
ENSG00000131196 E030 0.1272623 0.0124515502 3.414944e-01   18 79523924 79524035 112 + 0.000 0.117 11.103
ENSG00000131196 E031 0.3729107 0.2454474038 4.062758e-01   18 79527119 79527402 284 + 0.077 0.208 1.661
ENSG00000131196 E032 115.0676653 0.0018423394 5.464082e-23 1.913635e-20 18 79527528 79529325 1798 + 1.913 2.208 0.990

Help

Please Click HERE to learn more details about the results from DEXseq.