ENSG00000131238

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000439754 ENSG00000131238 No_inf pgKDN_inf PPT1 protein_coding protein_coding 2397.622 2558.635 2326.631 16.5772 9.87006 -0.1371314 159.8631 206.7510 142.2729 7.092275 12.285092 -0.5392021 0.06615833 0.080775 0.061100 -0.019675 2.054254e-01 4.700289e-36 FALSE TRUE
ENST00000449045 ENSG00000131238 No_inf pgKDN_inf PPT1 protein_coding protein_coding 2397.622 2558.635 2326.631 16.5772 9.87006 -0.1371314 181.3114 138.0253 182.5553 24.628708 22.435369 0.4033761 0.07638333 0.053775 0.078500 0.024725 3.683176e-01 4.700289e-36 FALSE TRUE
ENST00000530076 ENSG00000131238 No_inf pgKDN_inf PPT1 protein_coding protein_coding 2397.622 2558.635 2326.631 16.5772 9.87006 -0.1371314 446.1742 785.4549 326.0584 14.388183 21.036263 -1.2683722 0.18180833 0.307100 0.140075 -0.167025 1.755406e-23 4.700289e-36   TRUE
ENST00000642050 ENSG00000131238 No_inf pgKDN_inf PPT1 protein_coding protein_coding 2397.622 2558.635 2326.631 16.5772 9.87006 -0.1371314 1590.4303 1404.8266 1660.7534 13.148998 7.519283 0.2414443 0.66739167 0.549175 0.713825 0.164650 4.700289e-36 4.700289e-36 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131238 E001 5.6957953 2.328505e-02 1.840674e-01 4.611861e-01 1 40072710 40072711 2 - 0.720 0.891 0.676
ENSG00000131238 E002 22.2514348 1.074098e-02 7.317844e-01 8.933837e-01 1 40072712 40072718 7 - 1.347 1.377 0.105
ENSG00000131238 E003 51.4240852 9.350413e-04 3.719853e-01 6.598724e-01 1 40072719 40072725 7 - 1.692 1.735 0.144
ENSG00000131238 E004 55.5177468 5.457439e-04 2.099916e-01 4.944203e-01 1 40072726 40072728 3 - 1.717 1.773 0.188
ENSG00000131238 E005 101.8090245 8.630265e-04 8.842810e-03 7.405716e-02 1 40072729 40072737 9 - 1.957 2.046 0.299
ENSG00000131238 E006 2132.6495844 5.644780e-05 4.838523e-20 1.304804e-17 1 40072738 40072937 200 - 3.286 3.355 0.230
ENSG00000131238 E007 9788.5772326 4.999678e-05 2.389715e-40 2.148114e-37 1 40072938 40073457 520 - 3.959 4.009 0.167
ENSG00000131238 E008 4045.7206926 1.670179e-05 6.416717e-06 2.324239e-04 1 40073458 40073672 215 - 3.590 3.615 0.083
ENSG00000131238 E009 2302.7253028 1.855181e-05 8.780868e-01 9.585624e-01 1 40073673 40073785 113 - 3.358 3.361 0.008
ENSG00000131238 E010 1255.9357439 4.568403e-05 8.950117e-01 9.652908e-01 1 40073786 40073815 30 - 3.095 3.097 0.007
ENSG00000131238 E011 2897.8659133 1.700862e-05 2.363496e-01 5.254313e-01 1 40073816 40074023 208 - 3.461 3.458 -0.011
ENSG00000131238 E012 1769.0267563 1.912845e-05 4.982303e-01 7.586977e-01 1 40074024 40074126 103 - 3.246 3.244 -0.005
ENSG00000131238 E013 1517.3632144 3.335505e-05 7.666511e-02 2.830736e-01 1 40074127 40074183 57 - 3.184 3.174 -0.036
ENSG00000131238 E014 8.6135236 8.147887e-03 2.412914e-04 4.881400e-03 1 40075130 40075245 116 - 0.720 1.113 1.497
ENSG00000131238 E015 8.9849111 1.581605e-03 5.702442e-01 8.069146e-01 1 40076730 40076841 112 - 0.965 1.021 0.207
ENSG00000131238 E016 1532.5154008 2.750826e-05 1.933315e-06 8.255851e-05 1 40076842 40076913 72 - 3.202 3.167 -0.114
ENSG00000131238 E017 1752.4633302 2.790472e-05 5.867844e-06 2.154366e-04 1 40078560 40078658 99 - 3.258 3.227 -0.101
ENSG00000131238 E018 2.4598013 1.051761e-01 9.524164e-01 9.882190e-01 1 40078812 40078835 24 - 0.530 0.542 0.059
ENSG00000131238 E019 1026.5535657 3.851860e-05 4.501009e-06 1.717441e-04 1 40080397 40080446 50 - 3.031 2.990 -0.137
ENSG00000131238 E020 922.8033476 5.797976e-05 1.225560e-06 5.564366e-05 1 40080447 40080487 41 - 2.988 2.941 -0.157
ENSG00000131238 E021 0.6155403 1.432933e-02 7.949708e-01 9.220635e-01 1 40082184 40082321 138 - 0.185 0.225 0.354
ENSG00000131238 E022 1190.7261338 2.695875e-05 8.697020e-08 5.132003e-06 1 40089410 40089494 85 - 3.098 3.053 -0.148
ENSG00000131238 E023 656.5751474 1.789083e-04 2.208946e-03 2.753346e-02 1 40089495 40089512 18 - 2.835 2.798 -0.122
ENSG00000131238 E024 2.8281842 9.003370e-02 9.236048e-01 9.767173e-01 1 40089513 40089515 3 - 0.593 0.570 -0.107
ENSG00000131238 E025 0.4979743 3.340821e-02 4.108810e-01   1 40089516 40089582 67 - 0.102 0.225 1.354
ENSG00000131238 E026 1096.0251007 3.002627e-05 6.285601e-09 4.618632e-07 1 40091329 40091399 71 - 3.065 3.014 -0.169
ENSG00000131238 E027 1581.8189873 2.575598e-05 1.941126e-16 3.779519e-14 1 40092045 40092172 128 - 3.229 3.169 -0.201
ENSG00000131238 E028 8.3300033 1.671828e-03 4.951621e-01 7.564454e-01 1 40092173 40092397 225 - 1.001 0.939 -0.231
ENSG00000131238 E029 1027.4304429 1.085774e-04 1.618707e-11 1.774458e-09 1 40092398 40092500 103 - 3.045 2.979 -0.220
ENSG00000131238 E030 302.1670378 8.676907e-04 1.633886e-06 7.146959e-05 1 40092501 40092504 4 - 2.532 2.432 -0.333
ENSG00000131238 E031 295.2737360 1.196461e-03 4.335013e-06 1.664090e-04 1 40092505 40092507 3 - 2.523 2.420 -0.342
ENSG00000131238 E032 1.5872209 8.539619e-03 5.670296e-01 8.049423e-01 1 40093933 40094019 87 - 0.456 0.372 -0.453
ENSG00000131238 E033 0.1187032 1.185633e-02 4.546522e-01   1 40096809 40097110 302 - 0.102 0.000 -8.699
ENSG00000131238 E034 1.1091054 1.861687e-02 9.364047e-01 9.818623e-01 1 40097111 40097114 4 - 0.314 0.328 0.091
ENSG00000131238 E035 630.0181143 5.943606e-04 7.311568e-08 4.401140e-06 1 40097115 40097260 146 - 2.841 2.759 -0.273

Help

Please Click HERE to learn more details about the results from DEXseq.