ENSG00000131389

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000452151 ENSG00000131389 No_inf pgKDN_inf SLC6A6 protein_coding protein_coding 46.59831 23.02476 53.06971 0.7571826 1.072985 1.204348 23.407640 13.762618 25.355456 0.3604383 1.74822257 0.8810623 0.52190000 0.598775 0.478125 -0.120650 0.43072757 0.04114972 FALSE  
ENST00000610642 ENSG00000131389 No_inf pgKDN_inf SLC6A6 protein_coding nonsense_mediated_decay 46.59831 23.02476 53.06971 0.7571826 1.072985 1.204348 2.199459 2.371518 1.338438 0.1499214 0.09560698 -0.8205920 0.05790000 0.103325 0.025350 -0.077975 0.04114972 0.04114972 TRUE  
ENST00000622186 ENSG00000131389 No_inf pgKDN_inf SLC6A6 protein_coding protein_coding 46.59831 23.02476 53.06971 0.7571826 1.072985 1.204348 10.976607 4.394228 18.308703 1.4733713 1.30560377 2.0563561 0.23286667 0.191700 0.343925 0.152225 0.60628069 0.04114972 FALSE  
ENST00000649500 ENSG00000131389 No_inf pgKDN_inf SLC6A6 protein_coding nonsense_mediated_decay 46.59831 23.02476 53.06971 0.7571826 1.072985 1.204348 3.979432 1.667750 0.000000 1.6677502 0.00000000 -7.3903841 0.07671667 0.071675 0.000000 -0.071675 0.80123931 0.04114972 FALSE  
MSTRG.19762.7 ENSG00000131389 No_inf pgKDN_inf SLC6A6 protein_coding   46.59831 23.02476 53.06971 0.7571826 1.072985 1.204348 2.429304 0.000000 3.943086 0.0000000 1.67686612 8.6268356 0.04298333 0.000000 0.076125 0.076125 0.09167117 0.04114972 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131389 E001 0.0000000       3 14402576 14402583 8 +      
ENSG00000131389 E002 0.0000000       3 14402584 14402605 22 +      
ENSG00000131389 E003 0.1271363 0.0124380610 2.177405e-01   3 14402606 14402617 12 + 0.000 0.139 10.959
ENSG00000131389 E004 0.3807797 0.0394736261 1.883664e-02   3 14402618 14402619 2 + 0.000 0.329 14.127
ENSG00000131389 E005 0.3807797 0.0394736261 1.883664e-02   3 14402620 14402620 1 + 0.000 0.329 14.127
ENSG00000131389 E006 0.3807797 0.0394736261 1.883664e-02   3 14402621 14402624 4 + 0.000 0.329 14.127
ENSG00000131389 E007 1.3506688 0.0197002991 1.071497e-01 3.430160e-01 3 14402625 14402647 23 + 0.254 0.514 1.515
ENSG00000131389 E008 12.4845899 0.0042003730 2.600409e-01 5.526967e-01 3 14402648 14402847 200 + 1.060 1.175 0.416
ENSG00000131389 E009 0.1186381 0.0118225272 1.000000e+00   3 14411031 14411323 293 + 0.064 0.000 -11.885
ENSG00000131389 E010 7.3566710 0.0076308158 8.673434e-01 9.543096e-01 3 14416412 14416453 42 + 0.893 0.892 -0.005
ENSG00000131389 E011 0.4894151 0.1016977737 4.418561e-01   3 14432670 14432787 118 + 0.120 0.244 1.251
ENSG00000131389 E012 4.4595845 0.0671979285 9.545506e-01 9.889305e-01 3 14443624 14443627 4 + 0.710 0.712 0.011
ENSG00000131389 E013 19.9885772 0.0010052124 4.277589e-01 7.063266e-01 3 14443628 14443863 236 + 1.302 1.264 -0.132
ENSG00000131389 E014 0.1176306 0.0117827399 1.000000e+00   3 14443864 14444342 479 + 0.064 0.000 -11.885
ENSG00000131389 E015 0.6171442 0.1821716349 2.191939e-01 5.058408e-01 3 14444738 14444866 129 + 0.120 0.329 1.835
ENSG00000131389 E016 19.0729685 0.0007212277 1.629386e-02 1.108747e-01 3 14445717 14445851 135 + 1.315 1.153 -0.573
ENSG00000131389 E017 21.3027657 0.0060156319 2.254823e-01 5.133073e-01 3 14447582 14447816 235 + 1.338 1.264 -0.259
ENSG00000131389 E018 2.7740456 0.0325740305 6.753142e-01 8.655111e-01 3 14447817 14448188 372 + 0.568 0.514 -0.252
ENSG00000131389 E019 11.8002488 0.0040122437 3.975985e-01 6.818034e-01 3 14457950 14458082 133 + 1.094 1.034 -0.218
ENSG00000131389 E020 15.5957138 0.0009477071 7.615784e-01 9.069525e-01 3 14466516 14466650 135 + 1.175 1.217 0.150
ENSG00000131389 E021 13.3699802 0.0011422721 5.489892e-01 7.937645e-01 3 14467853 14467956 104 + 1.136 1.104 -0.116
ENSG00000131389 E022 13.6847578 0.0021064266 4.308849e-02 2.024032e-01 3 14468088 14468212 125 + 1.180 1.019 -0.580
ENSG00000131389 E023 11.4071436 0.0013816880 6.791125e-02 2.629568e-01 3 14472205 14472241 37 + 1.105 0.951 -0.566
ENSG00000131389 E024 14.8930984 0.0014767788 5.031692e-02 2.216607e-01 3 14472242 14472317 76 + 1.210 1.064 -0.526
ENSG00000131389 E025 15.0663870 0.0065889432 4.492245e-01 7.230132e-01 3 14477205 14477342 138 + 1.189 1.141 -0.169
ENSG00000131389 E026 21.6230612 0.0008080039 9.566357e-01 9.897163e-01 3 14478466 14478568 103 + 1.315 1.338 0.079
ENSG00000131389 E027 7.6617872 0.0017589508 1.991425e-07 1.088202e-05 3 14478569 14479026 458 + 0.667 1.197 2.013
ENSG00000131389 E028 27.5418747 0.0005040798 1.100433e-01 3.481018e-01 3 14479085 14479185 101 + 1.447 1.367 -0.275
ENSG00000131389 E029 35.4507454 0.0003831968 1.872237e-02 1.214274e-01 3 14481671 14481841 171 + 1.561 1.450 -0.380
ENSG00000131389 E030 743.5951985 0.0025953659 2.882232e-02 1.590772e-01 3 14484867 14489349 4483 + 2.826 2.865 0.129

Help

Please Click HERE to learn more details about the results from DEXseq.