ENSG00000131732

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000380199 ENSG00000131732 No_inf pgKDN_inf ZCCHC9 protein_coding protein_coding 20.10894 17.96393 21.33362 1.021996 2.041915 0.2478993 7.522607 5.585026 8.9937808 2.2047400 3.5084274 0.6863862 0.37449167 0.298775 0.445925 0.147150 0.88525158 0.03085122 FALSE TRUE
ENST00000407610 ENSG00000131732 No_inf pgKDN_inf ZCCHC9 protein_coding protein_coding 20.10894 17.96393 21.33362 1.021996 2.041915 0.2478993 8.708146 7.264723 8.8072057 1.3479417 3.2593989 0.2774293 0.43124167 0.410900 0.403325 -0.007575 0.98648691 0.03085122 FALSE TRUE
ENST00000510227 ENSG00000131732 No_inf pgKDN_inf ZCCHC9 protein_coding retained_intron 20.10894 17.96393 21.33362 1.021996 2.041915 0.2478993 1.413126 3.047029 0.3949248 0.5327454 0.3949248 -2.9164043 0.07523333 0.173975 0.014475 -0.159500 0.03085122 0.03085122   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131732 E001 0.0000000       5 81301587 81301589 3 +      
ENSG00000131732 E002 0.0000000       5 81301590 81301602 13 +      
ENSG00000131732 E003 0.2441403 0.0162318712 0.9925383197   5 81301603 81301622 20 + 0.095 0.095 -0.009
ENSG00000131732 E004 0.2441403 0.0162318712 0.9925383197   5 81301623 81301623 1 + 0.095 0.095 -0.009
ENSG00000131732 E005 1.1054249 0.0120991649 0.7558925048 0.903833334 5 81301624 81301640 17 + 0.297 0.346 0.313
ENSG00000131732 E006 2.5655705 0.1592837411 0.8622074445 0.952439320 5 81301641 81301661 21 + 0.568 0.536 -0.147
ENSG00000131732 E007 3.7931266 0.0253104975 0.8449510256 0.944763011 5 81301662 81301670 9 + 0.693 0.668 -0.102
ENSG00000131732 E008 2.4604082 0.0172813222 0.6821011219 0.868403713 5 81301671 81301698 28 + 0.506 0.566 0.281
ENSG00000131732 E009 2.5877231 0.1841568414 0.7803342407 0.915268722 5 81301699 81302055 357 + 0.507 0.594 0.404
ENSG00000131732 E010 7.1759365 0.0021884943 0.0380754713 0.188296577 5 81302056 81303726 1671 + 0.789 1.001 0.808
ENSG00000131732 E011 1.7124981 0.0081309832 0.9783854487 0.997044631 5 81303727 81303926 200 + 0.434 0.433 -0.009
ENSG00000131732 E012 6.7192545 0.0401375014 0.0071346755 0.063848962 5 81303927 81304740 814 + 0.670 1.022 1.370
ENSG00000131732 E013 38.6741375 0.0004112794 0.0399881761 0.193897536 5 81304741 81305141 401 + 1.641 1.555 -0.292
ENSG00000131732 E014 0.6088063 0.0160728843 0.6439745279 0.849177280 5 81308407 81308560 154 + 0.240 0.173 -0.594
ENSG00000131732 E015 18.1889348 0.0031292136 0.3131151887 0.606397163 5 81308561 81308667 107 + 1.315 1.251 -0.222
ENSG00000131732 E016 13.2122758 0.0035682909 0.7836729044 0.916783569 5 81308668 81308711 44 + 1.161 1.144 -0.062
ENSG00000131732 E017 2.2641349 0.0067437192 0.0005255968 0.009074116 5 81308712 81308945 234 + 0.173 0.691 2.991
ENSG00000131732 E018 16.3111398 0.0009096536 0.7145696704 0.884955126 5 81308946 81309038 93 + 1.223 1.251 0.100
ENSG00000131732 E019 0.0000000       5 81309039 81309158 120 +      
ENSG00000131732 E020 16.1615310 0.0032223557 0.7994722435 0.924785207 5 81311211 81311279 69 + 1.242 1.227 -0.053
ENSG00000131732 E021 65.2305970 0.0036154856 0.7594424312 0.905588424 5 81312544 81313297 754 + 1.826 1.816 -0.036

Help

Please Click HERE to learn more details about the results from DEXseq.