ENSG00000131747

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000423485 ENSG00000131747 No_inf pgKDN_inf TOP2A protein_coding protein_coding 61.50446 56.687 63.11554 3.710802 4.131656 0.1549514 35.959046 23.419893 44.166820 0.4379104 0.7626448 0.9149392 0.58547500 0.418800 0.708900 0.29010 0.001567303 0.001567303 FALSE TRUE
ENST00000577541 ENSG00000131747 No_inf pgKDN_inf TOP2A protein_coding protein_coding 61.50446 56.687 63.11554 3.710802 4.131656 0.1549514 5.090376 7.811105 3.346699 4.5167384 3.3466985 -1.2203295 0.07525833 0.124100 0.044350 -0.07975 0.837621224 0.001567303   FALSE
MSTRG.12633.3 ENSG00000131747 No_inf pgKDN_inf TOP2A protein_coding   61.50446 56.687 63.11554 3.710802 4.131656 0.1549514 17.809796 23.781862 13.171486 1.0176062 0.4897883 -0.8519552 0.29686667 0.426325 0.209925 -0.21640 0.006388673 0.001567303 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131747 E001 0.2444846 1.678044e-02 9.270565e-01   17 40388525 40388525 1 - 0.090 0.100 0.163
ENSG00000131747 E002 0.3713386 2.248368e-01 5.699987e-01   17 40388526 40388526 1 - 0.090 0.181 1.167
ENSG00000131747 E003 90.5963893 1.882163e-03 3.001453e-01 0.5930211186 17 40388527 40388858 332 - 1.944 1.980 0.120
ENSG00000131747 E004 292.4820920 8.317977e-05 7.148579e-03 0.0639125772 17 40388859 40389515 657 - 2.445 2.489 0.147
ENSG00000131747 E005 58.8175914 5.148892e-04 4.311544e-03 0.0447217499 17 40389516 40389561 46 - 1.718 1.830 0.378
ENSG00000131747 E006 69.2396701 2.214019e-04 2.595050e-03 0.0309557448 17 40389562 40389647 86 - 1.791 1.898 0.362
ENSG00000131747 E007 115.9552493 1.399628e-04 9.263699e-02 0.3161604449 17 40389965 40390164 200 - 2.045 2.090 0.152
ENSG00000131747 E008 86.6328792 1.679801e-03 9.224526e-01 0.9760949499 17 40391506 40391640 135 - 1.941 1.944 0.008
ENSG00000131747 E009 3.0755640 8.913582e-03 3.830744e-01 0.6691951842 17 40391641 40392067 427 - 0.549 0.666 0.515
ENSG00000131747 E010 46.9472944 3.428335e-04 8.108629e-01 0.9303800478 17 40392068 40392111 44 - 1.676 1.685 0.032
ENSG00000131747 E011 76.2815557 5.983347e-04 9.717801e-01 0.9946656601 17 40392218 40392341 124 - 1.888 1.888 0.001
ENSG00000131747 E012 85.9880765 1.814667e-04 8.350981e-02 0.2978848067 17 40392585 40392737 153 - 1.912 1.966 0.184
ENSG00000131747 E013 64.0500191 2.272286e-04 1.895804e-01 0.4683413921 17 40395449 40395539 91 - 1.789 1.837 0.162
ENSG00000131747 E014 50.6897215 1.244549e-03 7.608010e-01 0.9064670427 17 40396283 40396382 100 - 1.720 1.706 -0.049
ENSG00000131747 E015 36.2937266 3.964746e-04 9.745332e-01 0.9954113626 17 40396383 40396465 83 - 1.571 1.572 0.002
ENSG00000131747 E016 48.2731479 2.953059e-04 2.033597e-01 0.4858478132 17 40398558 40398641 84 - 1.665 1.719 0.182
ENSG00000131747 E017 82.4818625 1.986483e-04 3.368090e-02 0.1746342696 17 40398773 40398937 165 - 1.886 1.955 0.232
ENSG00000131747 E018 54.1059279 2.638140e-04 2.922184e-01 0.5856630584 17 40399040 40399131 92 - 1.720 1.762 0.141
ENSG00000131747 E019 0.2452102 1.682407e-02 9.265965e-01   17 40399132 40399261 130 - 0.090 0.100 0.167
ENSG00000131747 E020 77.6135702 1.847045e-03 9.556438e-01 0.9892827964 17 40399872 40400067 196 - 1.897 1.894 -0.010
ENSG00000131747 E021 75.8502084 3.438279e-04 4.565458e-01 0.7288551306 17 40400209 40400409 201 - 1.873 1.898 0.083
ENSG00000131747 E022 60.0698855 5.986844e-04 5.081657e-01 0.7664964503 17 40400529 40400663 135 - 1.799 1.772 -0.091
ENSG00000131747 E023 78.8293123 3.972127e-04 9.115589e-01 0.9717929946 17 40400850 40401081 232 - 1.904 1.899 -0.016
ENSG00000131747 E024 40.3938045 3.744974e-04 5.277806e-01 0.7796197614 17 40402906 40403054 149 - 1.602 1.631 0.097
ENSG00000131747 E025 35.7130788 4.427834e-04 2.527501e-01 0.5441179607 17 40404152 40404273 122 - 1.592 1.534 -0.199
ENSG00000131747 E026 34.1641325 9.989548e-03 1.166088e-01 0.3601843328 17 40404377 40404491 115 - 1.595 1.489 -0.362
ENSG00000131747 E027 28.4502794 8.298525e-03 1.245486e-01 0.3740828470 17 40404791 40404883 93 - 1.517 1.413 -0.356
ENSG00000131747 E028 24.4725073 5.594787e-04 1.790799e-01 0.4541387703 17 40406384 40406493 110 - 1.444 1.363 -0.281
ENSG00000131747 E029 25.3520500 5.597837e-04 2.782147e-01 0.5715331740 17 40406584 40406689 106 - 1.451 1.386 -0.224
ENSG00000131747 E030 27.0981809 5.097872e-04 2.359503e-02 0.1404607239 17 40406832 40406942 111 - 1.508 1.377 -0.450
ENSG00000131747 E031 28.0678529 4.692800e-03 6.424873e-02 0.2552522919 17 40407549 40407674 126 - 1.517 1.400 -0.402
ENSG00000131747 E032 2.0213146 6.845691e-03 6.282143e-05 0.0016027487 17 40407675 40407966 292 - 0.090 0.689 4.074
ENSG00000131747 E033 30.4735900 5.033271e-04 5.302832e-03 0.0517371480 17 40407967 40408124 158 - 1.566 1.413 -0.524
ENSG00000131747 E034 0.9687829 1.750088e-02 5.930278e-01 0.8205635238 17 40408125 40408244 120 - 0.333 0.250 -0.570
ENSG00000131747 E035 25.8152975 5.402452e-04 1.830178e-01 0.4597270335 17 40408492 40408630 139 - 1.465 1.386 -0.272
ENSG00000131747 E036 25.8207058 5.248863e-04 2.321567e-01 0.5208251517 17 40411109 40411246 138 - 1.462 1.391 -0.244
ENSG00000131747 E037 22.8317475 9.073083e-04 1.145718e-02 0.0879742825 17 40411354 40411455 102 - 1.448 1.288 -0.553
ENSG00000131747 E038 27.6627471 4.917987e-04 3.131487e-03 0.0356315611 17 40411645 40411818 174 - 1.532 1.363 -0.583
ENSG00000131747 E039 31.2775989 7.655732e-03 3.064287e-03 0.0350220920 17 40412759 40412971 213 - 1.592 1.400 -0.660
ENSG00000131747 E040 20.0682135 7.171268e-04 7.131444e-02 0.2705549061 17 40413195 40413292 98 - 1.378 1.258 -0.418
ENSG00000131747 E041 24.7411502 5.754246e-04 2.947792e-01 0.5880110185 17 40413480 40413625 146 - 1.440 1.377 -0.219
ENSG00000131747 E042 14.4973592 1.233133e-03 2.769726e-01 0.5703971043 17 40416005 40416068 64 - 1.229 1.145 -0.297
ENSG00000131747 E043 18.8690303 9.368085e-03 2.692118e-01 0.5627821122 17 40416422 40416512 91 - 1.338 1.252 -0.302
ENSG00000131747 E044 27.8182234 5.143218e-04 3.476782e-05 0.0009797114 17 40416740 40416895 156 - 1.560 1.322 -0.823
ENSG00000131747 E045 0.0000000       17 40417584 40417770 187 -      
ENSG00000131747 E046 15.0328130 9.407788e-04 2.698852e-02 0.1526694149 17 40417771 40417896 126 - 1.279 1.112 -0.595

Help

Please Click HERE to learn more details about the results from DEXseq.