ENSG00000131844

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340941 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 9.6441958 3.746926 10.102915 2.170369 3.383919 1.4285741 0.26056667 0.143900 0.241600 0.097700 0.83425581 0.03616367 FALSE TRUE
ENST00000682045 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 2.8047749 4.117918 1.220860 3.006402 1.220860 -1.7457478 0.08993333 0.163675 0.029725 -0.133950 0.76952823 0.03616367 FALSE TRUE
ENST00000682214 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 1.5264319 0.000000 4.579296 0.000000 3.894463 8.8421290 0.03771667 0.000000 0.113150 0.113150 0.59605823 0.03616367 FALSE TRUE
ENST00000682231 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding_CDS_not_defined 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 7.5328814 7.303891 10.738770 1.736117 2.074181 0.5554605 0.21779167 0.280500 0.256625 -0.023875 0.97812344 0.03616367 FALSE TRUE
ENST00000683429 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 0.6182564 1.854769 0.000000 1.854769 0.000000 -7.5428532 0.02225833 0.066775 0.000000 -0.066775 0.82947847 0.03616367 FALSE TRUE
ENST00000683789 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 2.5229343 0.000000 5.763667 0.000000 2.468751 9.1733442 0.06278333 0.000000 0.140325 0.140325 0.03616367 0.03616367 FALSE TRUE
ENST00000684530 ENSG00000131844 No_inf pgKDN_inf MCCC2 protein_coding protein_coding 35.36342 26.14456 41.50436 0.6583729 0.7828153 0.6665481 1.5633049 1.701060 0.000000 1.701060 0.000000 -7.4187469 0.04710000 0.061250 0.000000 -0.061250 0.82900515 0.03616367 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131844 E001 0.4903851 0.0157918024 7.026257e-01   5 71579531 71580217 687 + 0.147 0.203 0.561
ENSG00000131844 E002 1.2350776 0.0105598303 2.197853e-01 0.506384907 5 71580218 71581043 826 + 0.257 0.445 1.146
ENSG00000131844 E003 0.2435110 0.0160763463 7.644693e-01   5 71582450 71582573 124 + 0.080 0.113 0.561
ENSG00000131844 E004 0.2543986 0.0160393904 1.361000e-01   5 71582951 71583018 68 + 0.000 0.203 12.633
ENSG00000131844 E005 0.0000000       5 71583822 71583951 130 +      
ENSG00000131844 E006 0.0000000       5 71584033 71584166 134 +      
ENSG00000131844 E007 0.1187032 0.0117968773 7.980406e-01   5 71586745 71586786 42 + 0.080 0.000 -11.702
ENSG00000131844 E008 0.6097487 0.0157648590 9.830534e-01 0.998690264 5 71586787 71586850 64 + 0.205 0.203 -0.024
ENSG00000131844 E009 0.0000000       5 71587276 71587277 2 +      
ENSG00000131844 E010 0.0000000       5 71587278 71587279 2 +      
ENSG00000131844 E011 0.0000000       5 71587280 71587287 8 +      
ENSG00000131844 E012 0.0000000       5 71587288 71587295 8 +      
ENSG00000131844 E013 0.0000000       5 71587296 71587297 2 +      
ENSG00000131844 E014 0.0000000       5 71587298 71587302 5 +      
ENSG00000131844 E015 0.0000000       5 71587303 71587303 1 +      
ENSG00000131844 E016 0.0000000       5 71587304 71587305 2 +      
ENSG00000131844 E017 0.0000000       5 71587306 71587308 3 +      
ENSG00000131844 E018 0.0000000       5 71587309 71587316 8 +      
ENSG00000131844 E019 0.0000000       5 71587317 71587333 17 +      
ENSG00000131844 E020 0.0000000       5 71587334 71587336 3 +      
ENSG00000131844 E021 0.2372762 0.2286498881 4.599360e-01   5 71587337 71587339 3 + 0.147 0.000 -12.142
ENSG00000131844 E022 0.7170586 0.1216795103 2.605730e-01 0.553115308 5 71587340 71587355 16 + 0.303 0.113 -1.761
ENSG00000131844 E023 1.4593295 0.4837093466 9.961283e-01 1.000000000 5 71587356 71587369 14 + 0.382 0.396 0.078
ENSG00000131844 E024 5.4953776 0.1212412359 1.763784e-02 0.116728629 5 71587370 71587442 73 + 0.937 0.529 -1.685
ENSG00000131844 E025 8.4308016 0.0165682157 3.701365e-02 0.185256706 5 71587443 71587554 112 + 1.052 0.823 -0.863
ENSG00000131844 E026 0.0000000       5 71592871 71592925 55 +      
ENSG00000131844 E027 10.5108533 0.0013526208 1.122732e-01 0.352208590 5 71592926 71592992 67 + 1.110 0.970 -0.514
ENSG00000131844 E028 17.3075069 0.0007576085 1.266184e-01 0.377239283 5 71596280 71596364 85 + 1.300 1.192 -0.379
ENSG00000131844 E029 17.7756306 0.0026529617 8.835965e-01 0.960882021 5 71599659 71599760 102 + 1.263 1.275 0.042
ENSG00000131844 E030 8.3784066 0.0019198473 6.377680e-01 0.845466379 5 71602506 71602510 5 + 0.985 0.941 -0.165
ENSG00000131844 E031 18.1287736 0.0050047010 3.021455e-02 0.163482287 5 71602511 71602633 123 + 1.338 1.175 -0.571
ENSG00000131844 E032 0.0000000       5 71602634 71603065 432 +      
ENSG00000131844 E033 17.0159731 0.0086331764 1.147502e-02 0.088048640 5 71604356 71604468 113 + 1.325 1.120 -0.725
ENSG00000131844 E034 12.4104023 0.0036393196 9.535934e-01 0.988578732 5 71626640 71626753 114 + 1.124 1.120 -0.012
ENSG00000131844 E035 0.0000000       5 71631151 71631279 129 +      
ENSG00000131844 E036 0.0000000       5 71631539 71632120 582 +      
ENSG00000131844 E037 17.6801605 0.0020142964 1.767229e-01 0.451039791 5 71632121 71632185 65 + 1.304 1.209 -0.336
ENSG00000131844 E038 1.7767317 0.0693299998 8.718459e-06 0.000303173 5 71633138 71634942 1805 + 0.000 0.713 14.951
ENSG00000131844 E039 10.2523464 0.0185802224 6.948068e-02 0.266432355 5 71634943 71634952 10 + 1.117 0.926 -0.702
ENSG00000131844 E040 17.9120467 0.0021355435 1.008405e-01 0.331488404 5 71634953 71635042 90 + 1.317 1.200 -0.410
ENSG00000131844 E041 21.5897581 0.0105959085 4.144520e-01 0.694626204 5 71635151 71635246 96 + 1.372 1.314 -0.202
ENSG00000131844 E042 1.9680589 0.0595446556 2.492824e-01 0.540159709 5 71635247 71636103 857 + 0.382 0.565 0.924
ENSG00000131844 E043 0.9740999 0.2794577144 9.831013e-01 0.998690264 5 71636104 71636167 64 + 0.303 0.277 -0.178
ENSG00000131844 E044 0.9798888 0.0128843265 5.907819e-01 0.818868069 5 71636168 71636711 544 + 0.257 0.340 0.561
ENSG00000131844 E045 0.8707594 0.2867881599 2.389371e-01 0.527904523 5 71639622 71639811 190 + 0.147 0.396 1.884
ENSG00000131844 E046 0.3729107 0.2448992510 4.308497e-01   5 71639812 71639851 40 + 0.080 0.203 1.561
ENSG00000131844 E047 1.4880572 0.0138305710 7.254382e-02 0.273377468 5 71639852 71640009 158 + 0.257 0.529 1.561
ENSG00000131844 E048 1.5135525 0.0178990418 2.523371e-04 0.005059312 5 71640010 71640384 375 + 0.080 0.630 4.021
ENSG00000131844 E049 0.1186381 0.0117970360 7.980629e-01   5 71640385 71640415 31 + 0.080 0.000 -11.702
ENSG00000131844 E050 0.4985363 0.0157185016 1.682129e-01   5 71640416 71640544 129 + 0.080 0.277 2.146
ENSG00000131844 E051 0.7525266 0.0134031025 3.282130e-02 0.171729904 5 71640545 71640561 17 + 0.080 0.396 2.883
ENSG00000131844 E052 0.9876045 0.0114631294 2.146791e-01 0.500216082 5 71640562 71640704 143 + 0.205 0.396 1.298
ENSG00000131844 E053 0.8701911 0.0133814566 1.011073e-01 0.332062050 5 71640705 71641002 298 + 0.147 0.396 1.883
ENSG00000131844 E054 19.4396358 0.0008264640 7.768231e-01 0.914246591 5 71641003 71641075 73 + 1.313 1.295 -0.061
ENSG00000131844 E055 0.7365719 0.0646706321 6.510628e-01 0.853024314 5 71641076 71641083 8 + 0.205 0.277 0.561
ENSG00000131844 E056 2.3251513 0.0330462398 5.614846e-01 0.801843176 5 71641084 71641195 112 + 0.479 0.565 0.409
ENSG00000131844 E057 11.7693859 0.0013625700 3.813823e-02 0.188503225 5 71641196 71642663 1468 + 1.020 1.192 0.621
ENSG00000131844 E058 1.9500914 0.0071784183 7.937653e-01 0.921358782 5 71642664 71642727 64 + 0.449 0.489 0.199
ENSG00000131844 E059 0.3714026 0.0165027718 3.721473e-01   5 71643043 71643062 20 + 0.080 0.203 1.561
ENSG00000131844 E060 4.7201626 0.0142894519 3.231320e-04 0.006182264 5 71643063 71643770 708 + 0.507 0.956 1.857
ENSG00000131844 E061 0.9877331 0.0120232613 2.149936e-01 0.500646128 5 71643771 71643818 48 + 0.205 0.396 1.298
ENSG00000131844 E062 13.0478068 0.0277228436 5.769999e-01 0.810900116 5 71643819 71643845 27 + 1.117 1.175 0.209
ENSG00000131844 E063 16.0644916 0.0301967411 9.128893e-01 0.972361627 5 71643846 71643895 50 + 1.223 1.232 0.031
ENSG00000131844 E064 5.9556099 0.0024046184 9.003224e-05 0.002180422 5 71643896 71646210 2315 + 0.604 1.034 1.699
ENSG00000131844 E065 11.6802302 0.0158840890 9.744485e-01 0.995411363 5 71646211 71646223 13 + 1.096 1.100 0.013
ENSG00000131844 E066 16.4217675 0.0095657604 9.519590e-01 0.987911698 5 71646224 71646277 54 + 1.234 1.239 0.021
ENSG00000131844 E067 0.1268540 0.0122819561 3.614902e-01   5 71649070 71649096 27 + 0.000 0.113 11.695
ENSG00000131844 E068 34.9740391 0.0173229817 7.784097e-01 0.914866436 5 71649097 71649253 157 + 1.559 1.539 -0.070
ENSG00000131844 E069 0.0000000       5 71649254 71649296 43 +      
ENSG00000131844 E070 0.0000000       5 71649297 71649348 52 +      
ENSG00000131844 E071 0.4988535 0.0263587165 1.704376e-01   5 71649349 71650068 720 + 0.080 0.277 2.146
ENSG00000131844 E072 29.3294104 0.0005165765 7.467182e-01 0.899805638 5 71650069 71650183 115 + 1.469 1.488 0.066
ENSG00000131844 E073 0.0000000       5 71650184 71650352 169 +      
ENSG00000131844 E074 0.6254866 0.1919130954 1.195683e-01 0.365520969 5 71650353 71651234 882 + 0.080 0.340 2.560
ENSG00000131844 E075 0.2448930 0.0162387037 7.645830e-01   5 71651235 71651509 275 + 0.080 0.113 0.561
ENSG00000131844 E076 0.2441377 0.0160760873 7.644174e-01   5 71651510 71651927 418 + 0.080 0.113 0.561
ENSG00000131844 E077 0.0000000       5 71651928 71651992 65 +      
ENSG00000131844 E078 1.1244636 0.0130708964 2.443472e-02 0.143417391 5 71651993 71652668 676 + 0.147 0.489 2.369
ENSG00000131844 E079 28.1195305 0.0115379027 6.965644e-01 0.876096032 5 71652669 71652754 86 + 1.447 1.475 0.095
ENSG00000131844 E080 0.6154143 0.0158772090 3.837149e-01 0.669815142 5 71652755 71653850 1096 + 0.147 0.277 1.146
ENSG00000131844 E081 321.3090590 0.0000943959 4.645727e-01 0.734012935 5 71656743 71658706 1964 + 2.498 2.509 0.037

Help

Please Click HERE to learn more details about the results from DEXseq.