ENSG00000131981

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000254301 ENSG00000131981 No_inf pgKDN_inf LGALS3 protein_coding protein_coding 91.7568 49.33684 115.0599 1.603032 1.571077 1.221481 83.73089 43.414147 108.119070 1.263871 1.8580666 1.3161850 0.90628333 0.880475 0.939600 0.059125 0.02041354 0.02041354 FALSE  
MSTRG.8553.2 ENSG00000131981 No_inf pgKDN_inf LGALS3 protein_coding   91.7568 49.33684 115.0599 1.603032 1.571077 1.221481 4.75440 3.180205 4.406698 1.098305 0.4003762 0.4693191 0.05359167 0.062400 0.038325 -0.024075 0.92694990 0.02041354 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131981 E001 0.0000000       14 55124110 55124158 49 +      
ENSG00000131981 E002 0.0000000       14 55129179 55129251 73 +      
ENSG00000131981 E003 0.9970726 0.0173919971 0.0182912410 0.119467607 14 55129252 55129255 4 + 0.129 0.487 2.575
ENSG00000131981 E004 2.9123904 0.0048045961 0.6847249740 0.869574952 14 55129256 55129259 4 + 0.557 0.613 0.253
ENSG00000131981 E005 13.6418460 0.0011774771 0.5652611558 0.804188741 14 55129260 55129300 41 + 1.163 1.116 -0.166
ENSG00000131981 E006 0.7345264 0.5101212762 0.6777411896 0.866569578 14 55130061 55130116 56 + 0.182 0.309 0.990
ENSG00000131981 E007 1.2327820 0.0107304112 0.0905338886 0.312462709 14 55133352 55133392 41 + 0.229 0.487 1.575
ENSG00000131981 E008 1.9592497 0.0078627080 0.1793207885 0.454401776 14 55137188 55137368 181 + 0.378 0.575 0.990
ENSG00000131981 E009 0.6256450 0.1769099264 0.0607115393 0.247392962 14 55137369 55137369 1 + 0.070 0.377 2.991
ENSG00000131981 E010 20.0466410 0.0008648468 0.5454124635 0.791355746 14 55137370 55137391 22 + 1.318 1.277 -0.142
ENSG00000131981 E011 2.3663407 0.0064963669 0.0004115139 0.007484209 14 55137392 55137626 235 + 0.271 0.766 2.476
ENSG00000131981 E012 1.3434880 0.0099665350 0.4184345662 0.698046703 14 55137627 55137694 68 + 0.310 0.435 0.727
ENSG00000131981 E013 4.7280490 0.0030438004 0.7549681821 0.903589405 14 55137695 55138043 349 + 0.728 0.766 0.154
ENSG00000131981 E014 0.7273830 0.0682731244 0.9977496258 1.000000000 14 55138044 55138044 1 + 0.229 0.228 -0.010
ENSG00000131981 E015 95.1948889 0.0012612730 0.4018739729 0.684996867 14 55138045 55138368 324 + 1.954 1.980 0.088
ENSG00000131981 E016 63.8591303 0.0006406491 0.8557794791 0.949254682 14 55140275 55140363 89 + 1.795 1.788 -0.022
ENSG00000131981 E017 0.0000000       14 55140364 55140440 77 +      
ENSG00000131981 E018 122.3411247 0.0020100408 0.3712690124 0.659308067 14 55142584 55142749 166 + 2.080 2.055 -0.083
ENSG00000131981 E019 0.1186381 0.0118737076 1.0000000000   14 55142750 55142755 6 + 0.070 0.000 -7.849
ENSG00000131981 E020 0.3715287 0.1887927031 0.2899633197   14 55143448 55143721 274 + 0.070 0.228 1.991
ENSG00000131981 E021 115.6577712 0.0001871631 0.3218594772 0.614870134 14 55145116 55145423 308 + 2.056 2.030 -0.085

Help

Please Click HERE to learn more details about the results from DEXseq.