ENSG00000132155

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000251849 ENSG00000132155 No_inf pgKDN_inf RAF1 protein_coding protein_coding 58.48131 49.73495 65.0834 1.454413 1.524814 0.3879613 18.890331 8.448175 22.620398 1.163222 2.2704463 1.4198436 0.3134667 0.170000 0.347200 0.177200 0.04461864 0.04461864 FALSE TRUE
ENST00000688543 ENSG00000132155 No_inf pgKDN_inf RAF1 protein_coding protein_coding 58.48131 49.73495 65.0834 1.454413 1.524814 0.3879613 3.104621 3.562560 4.575633 1.192683 0.6695918 0.3601626 0.0542500 0.072575 0.070875 -0.001700 0.95634752 0.04461864 FALSE TRUE
ENST00000690585 ENSG00000132155 No_inf pgKDN_inf RAF1 protein_coding nonsense_mediated_decay 58.48131 49.73495 65.0834 1.454413 1.524814 0.3879613 12.749681 7.202777 17.651546 4.437399 2.3949320 1.2919850 0.2116417 0.139450 0.271800 0.132350 0.48480017 0.04461864 FALSE TRUE
ENST00000691888 ENSG00000132155 No_inf pgKDN_inf RAF1 protein_coding protein_coding 58.48131 49.73495 65.0834 1.454413 1.524814 0.3879613 6.894167 12.547996 2.808287 4.974050 2.8082868 -2.1557159 0.1277000 0.257175 0.041600 -0.215575 0.33821788 0.04461864 FALSE TRUE
MSTRG.19755.48 ENSG00000132155 No_inf pgKDN_inf RAF1 protein_coding   58.48131 49.73495 65.0834 1.454413 1.524814 0.3879613 3.750454 3.753927 6.252315 2.258272 2.3600108 0.7344573 0.0635000 0.073350 0.096775 0.023425 0.83444762 0.04461864 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132155 E001 0.0000000       3 12582101 12582115 15 -      
ENSG00000132155 E002 0.0000000       3 12582116 12583600 1485 -      
ENSG00000132155 E003 0.0000000       3 12583601 12583605 5 -      
ENSG00000132155 E004 0.0000000       3 12583606 12583607 2 -      
ENSG00000132155 E005 0.0000000       3 12583608 12583612 5 -      
ENSG00000132155 E006 0.0000000       3 12583613 12583614 2 -      
ENSG00000132155 E007 0.0000000       3 12583615 12583615 1 -      
ENSG00000132155 E008 0.0000000       3 12583616 12583620 5 -      
ENSG00000132155 E009 0.0000000       3 12583621 12583623 3 -      
ENSG00000132155 E010 0.0000000       3 12583624 12583629 6 -      
ENSG00000132155 E011 0.0000000       3 12583630 12583633 4 -      
ENSG00000132155 E012 0.0000000       3 12583634 12583637 4 -      
ENSG00000132155 E013 0.0000000       3 12583638 12583638 1 -      
ENSG00000132155 E014 0.0000000       3 12583639 12583641 3 -      
ENSG00000132155 E015 0.0000000       3 12583642 12583643 2 -      
ENSG00000132155 E016 0.0000000       3 12583644 12583648 5 -      
ENSG00000132155 E017 0.0000000       3 12583649 12583656 8 -      
ENSG00000132155 E018 0.0000000       3 12583657 12583698 42 -      
ENSG00000132155 E019 0.0000000       3 12583699 12583700 2 -      
ENSG00000132155 E020 0.0000000       3 12583701 12583718 18 -      
ENSG00000132155 E021 0.0000000       3 12583719 12583739 21 -      
ENSG00000132155 E022 0.0000000       3 12583740 12583762 23 -      
ENSG00000132155 E023 0.0000000       3 12583763 12583763 1 -      
ENSG00000132155 E024 0.0000000       3 12583764 12583766 3 -      
ENSG00000132155 E025 0.0000000       3 12583767 12583811 45 -      
ENSG00000132155 E026 0.0000000       3 12583812 12583826 15 -      
ENSG00000132155 E027 0.0000000       3 12583827 12583919 93 -      
ENSG00000132155 E028 0.0000000       3 12583920 12583927 8 -      
ENSG00000132155 E029 0.0000000       3 12583928 12584657 730 -      
ENSG00000132155 E030 0.0000000       3 12584847 12584888 42 -      
ENSG00000132155 E031 0.0000000       3 12584889 12584981 93 -      
ENSG00000132155 E032 0.0000000       3 12584982 12585121 140 -      
ENSG00000132155 E033 0.0000000       3 12585122 12585253 132 -      
ENSG00000132155 E034 0.0000000       3 12585254 12585406 153 -      
ENSG00000132155 E035 0.0000000       3 12585407 12585680 274 -      
ENSG00000132155 E036 0.0000000       3 12585681 12585781 101 -      
ENSG00000132155 E037 0.0000000       3 12585782 12585799 18 -      
ENSG00000132155 E038 0.0000000       3 12585800 12585819 20 -      
ENSG00000132155 E039 1.8767704 0.0075790508 7.339065e-03 6.518048e-02 3 12585820 12586274 455 - 0.224 0.624 2.250
ENSG00000132155 E040 4.6256849 0.0030247856 6.131254e-05 1.570941e-03 3 12586275 12586344 70 - 0.446 0.942 2.108
ENSG00000132155 E041 10.9578904 0.0031809198 6.138322e-07 2.996057e-05 3 12586345 12586640 296 - 0.805 1.257 1.665
ENSG00000132155 E042 6.1555198 0.0076212156 2.103806e-08 1.407775e-06 3 12586641 12586846 206 - 0.410 1.087 2.835
ENSG00000132155 E043 23.8852748 0.0012122398 4.256570e-13 5.841574e-11 3 12586847 12587590 744 - 1.118 1.578 1.604
ENSG00000132155 E044 10.2834305 0.0013592233 4.547004e-01 7.273858e-01 3 12587591 12587637 47 - 1.018 1.087 0.250
ENSG00000132155 E045 2.7311043 0.0286606693 5.078931e-02 2.229224e-01 3 12587638 12587978 341 - 0.410 0.699 1.350
ENSG00000132155 E046 19.0537150 0.0008422339 9.621237e-06 3.294678e-04 3 12587979 12589894 1916 - 1.133 1.434 1.057
ENSG00000132155 E047 1.3619018 0.0775066356 2.826376e-01 5.762589e-01 3 12589895 12590085 191 - 0.278 0.458 1.057
ENSG00000132155 E048 3.5936118 0.0039588926 3.563547e-02 1.808907e-01 3 12590086 12590797 712 - 0.511 0.783 1.176
ENSG00000132155 E049 46.4175639 0.0003156134 2.058056e-01 4.892203e-01 3 12590798 12590974 177 - 1.698 1.648 -0.169
ENSG00000132155 E050 0.9801137 0.0122014561 8.189235e-01 9.340393e-01 3 12590975 12591176 202 - 0.278 0.315 0.250
ENSG00000132155 E051 2.5601237 0.0904910083 8.248092e-01 9.364583e-01 3 12591177 12591707 531 - 0.567 0.532 -0.165
ENSG00000132155 E052 29.8766453 0.0030091503 5.825795e-01 8.140436e-01 3 12591708 12591775 68 - 1.502 1.475 -0.093
ENSG00000132155 E053 17.2630259 0.0126073756 4.653576e-01 7.344140e-01 3 12591776 12591789 14 - 1.229 1.294 0.229
ENSG00000132155 E054 14.9098441 0.0079000142 7.482768e-01 9.006397e-01 3 12591790 12591792 3 - 1.187 1.217 0.108
ENSG00000132155 E055 0.5070043 0.0158728413 3.038593e-02 1.640147e-01 3 12591793 12591851 59 - 0.000 0.315 14.929
ENSG00000132155 E056 4.3369161 0.0032893781 1.964993e-02 1.255686e-01 3 12591852 12592822 971 - 0.567 0.854 1.189
ENSG00000132155 E057 0.8509001 0.0126582645 8.720547e-01 9.562161e-01 3 12598936 12599112 177 - 0.278 0.255 -0.165
ENSG00000132155 E058 1.0947882 0.0761784538 9.416766e-01 9.835583e-01 3 12599113 12599225 113 - 0.327 0.316 -0.071
ENSG00000132155 E059 1.1143934 0.0107104095 2.147177e-01 5.002482e-01 3 12599226 12599690 465 - 0.224 0.415 1.250
ENSG00000132155 E060 17.5764941 0.0022199036 9.837553e-01 9.986903e-01 3 12599691 12599702 12 - 1.267 1.270 0.009
ENSG00000132155 E061 29.2955410 0.0005106088 8.772195e-01 9.583262e-01 3 12599703 12599806 104 - 1.483 1.478 -0.015
ENSG00000132155 E062 12.0634999 0.0017669206 4.916798e-01 7.539574e-01 3 12599807 12599808 2 - 1.140 1.087 -0.190
ENSG00000132155 E063 0.7538810 0.0148307972 6.128433e-02 2.486156e-01 3 12599809 12600151 343 - 0.088 0.368 2.572
ENSG00000132155 E064 20.0867316 0.0010578946 2.260519e-01 5.139700e-01 3 12600152 12600204 53 - 1.357 1.282 -0.262
ENSG00000132155 E065 22.0424603 0.0006649516 2.854402e-01 5.791276e-01 3 12600205 12600267 63 - 1.390 1.328 -0.216
ENSG00000132155 E066 11.8357943 0.0204536337 7.985838e-01 9.242309e-01 3 12600268 12600279 12 - 1.118 1.096 -0.079
ENSG00000132155 E067 0.5079806 0.0720666374 3.513362e-02 1.794240e-01 3 12600280 12600387 108 - 0.000 0.315 14.824
ENSG00000132155 E068 15.4653828 0.0334699620 5.134582e-01 7.702729e-01 3 12600388 12600415 28 - 1.246 1.180 -0.231
ENSG00000132155 E069 0.9886417 0.0119038538 3.512583e-01 6.415865e-01 3 12600416 12601364 949 - 0.224 0.368 0.987
ENSG00000132155 E070 0.4995438 0.0152404576 2.467920e-01   3 12603478 12603537 60 - 0.088 0.255 1.835
ENSG00000132155 E071 36.1283849 0.0025368303 6.775681e-02 2.627172e-01 3 12604136 12604289 154 - 1.610 1.519 -0.311
ENSG00000132155 E072 0.2533610 0.0160833961 1.911989e-01   3 12604290 12605087 798 - 0.000 0.186 14.000
ENSG00000132155 E073 0.0000000       3 12605263 12605825 563 -      
ENSG00000132155 E074 0.0000000       3 12605826 12606048 223 -      
ENSG00000132155 E075 0.1176306 0.0117564130 6.326903e-01   3 12606049 12606200 152 - 0.088 0.000 -12.945
ENSG00000132155 E076 25.1007385 0.0006083977 4.509293e-03 4.610217e-02 3 12606201 12606299 99 - 1.486 1.323 -0.565
ENSG00000132155 E077 0.1186381 0.0118027528 6.327158e-01   3 12606508 12606622 115 - 0.088 0.000 -12.945
ENSG00000132155 E078 0.0000000       3 12607918 12607974 57 -      
ENSG00000132155 E079 0.2362687 0.0156487669 3.038226e-01   3 12608446 12608765 320 - 0.161 0.000 -13.895
ENSG00000132155 E080 33.2258186 0.0004399480 1.345621e-03 1.882612e-02 3 12608766 12608923 158 - 1.603 1.442 -0.549
ENSG00000132155 E081 0.2363338 0.0157150361 3.036716e-01   3 12608924 12609164 241 - 0.161 0.000 -13.895
ENSG00000132155 E082 0.0000000       3 12609165 12609232 68 -      
ENSG00000132155 E083 21.9654075 0.0007142585 8.051372e-01 9.278667e-01 3 12609233 12609335 103 - 1.366 1.355 -0.039
ENSG00000132155 E084 0.1187032 0.0118720577 6.326109e-01   3 12610654 12610680 27 - 0.088 0.000 -12.945
ENSG00000132155 E085 16.3555445 0.0008520501 1.464392e-02 1.033641e-01 3 12611950 12612008 59 - 1.312 1.140 -0.608
ENSG00000132155 E086 17.6746517 0.0008016293 4.129648e-03 4.344061e-02 3 12612009 12612062 54 - 1.353 1.157 -0.691
ENSG00000132155 E087 0.0000000       3 12612063 12612098 36 -      
ENSG00000132155 E088 0.1268540 0.0124293071 4.563013e-01   3 12618485 12618514 30 - 0.000 0.103 13.052
ENSG00000132155 E089 43.3312201 0.0005009891 1.607305e-03 2.157501e-02 3 12618515 12618747 233 - 1.706 1.569 -0.467
ENSG00000132155 E090 0.1186381 0.0118027528 6.327158e-01   3 12622903 12622995 93 - 0.088 0.000 -12.945
ENSG00000132155 E091 0.1176306 0.0117564130 6.326903e-01   3 12626327 12626419 93 - 0.088 0.000 -12.945
ENSG00000132155 E092 0.0000000       3 12629622 12629724 103 -      
ENSG00000132155 E093 0.2539903 0.0161178683 1.911364e-01   3 12648570 12649086 517 - 0.000 0.186 14.000
ENSG00000132155 E094 0.8822121 0.8079980012 5.076173e-01 7.660064e-01 3 12661337 12662601 1265 - 0.088 0.416 2.836
ENSG00000132155 E095 0.2459655 0.0164287557 8.990796e-01   3 12662602 12662724 123 - 0.088 0.103 0.250
ENSG00000132155 E096 0.3543453 0.0158239171 1.385291e-01   3 12662725 12663060 336 - 0.224 0.000 -14.438
ENSG00000132155 E097 0.3730368 0.0166363418 4.870793e-01   3 12663098 12663368 271 - 0.088 0.186 1.250
ENSG00000132155 E098 0.3723465 0.0166298028 4.872708e-01   3 12663369 12663508 140 - 0.088 0.186 1.250
ENSG00000132155 E099 28.2021014 0.0005593781 9.416176e-02 3.193340e-01 3 12663813 12664201 389 - 1.505 1.416 -0.304

Help

Please Click HERE to learn more details about the results from DEXseq.