ENSG00000132205

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000254528 ENSG00000132205 No_inf pgKDN_inf EMILIN2 protein_coding protein_coding 186.991 36.17877 255.861 0.688459 1.685852 2.821802 182.550041 29.958389 252.974521 0.3025171 1.6587141 3.0775357 0.93390000 0.828675 0.988725 0.16005 1.681537e-42 1.681537e-42 FALSE TRUE
ENST00000308080 ENSG00000132205 No_inf pgKDN_inf EMILIN2 protein_coding protein_coding_CDS_not_defined 186.991 36.17877 255.861 0.688459 1.685852 2.821802 2.224321 3.263667 1.671032 0.2204540 0.2127067 -0.9615602 0.03435833 0.090100 0.006500 -0.08360 1.556195e-07 1.681537e-42 FALSE FALSE
ENST00000583776 ENSG00000132205 No_inf pgKDN_inf EMILIN2 protein_coding retained_intron 186.991 36.17877 255.861 0.688459 1.685852 2.821802 2.216650 2.956717 1.215403 0.3663313 0.2422421 -1.2756115 0.03174167 0.081275 0.004725 -0.07655 1.656203e-06 1.681537e-42 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132205 E001 72.87168 2.041111e-04 1.346414e-02 9.753858e-02 18 2847006 2847322 317 + 1.733 1.591 -0.480
ENSG00000132205 E002 33.49564 1.157932e-03 6.410372e-02 2.549683e-01 18 2847809 2847931 123 + 1.407 1.251 -0.542
ENSG00000132205 E003 136.14578 9.543783e-04 3.052607e-04 5.885563e-03 18 2884964 2885139 176 + 2.002 1.842 -0.538
ENSG00000132205 E004 1973.40909 1.977427e-04 1.561184e-27 7.585668e-25 18 2890561 2892486 1926 + 3.153 3.051 -0.337
ENSG00000132205 E005 13.18831 1.028525e-03 4.236040e-28 2.196794e-25 18 2906215 2906525 311 + 0.718 1.605 3.215
ENSG00000132205 E006 10.59933 1.900020e-03 4.464437e-22 1.468201e-19 18 2906569 2906782 214 + 0.649 1.507 3.171
ENSG00000132205 E007 242.75985 9.510347e-05 8.868750e-01 9.621398e-01 18 2906783 2906989 207 + 2.232 2.230 -0.007
ENSG00000132205 E008 159.47478 1.120951e-04 7.200698e-01 8.872597e-01 18 2906990 2907085 96 + 2.050 2.056 0.021
ENSG00000132205 E009 108.85653 1.466864e-04 6.605206e-01 8.583058e-01 18 2908943 2908975 33 + 1.885 1.897 0.041
ENSG00000132205 E010 232.91939 9.048847e-05 8.999501e-02 3.115998e-01 18 2909691 2909819 129 + 2.208 2.249 0.137
ENSG00000132205 E011 1473.81939 3.010771e-05 6.492942e-26 2.870413e-23 18 2913067 2916003 2937 + 2.999 3.088 0.294

Help

Please Click HERE to learn more details about the results from DEXseq.