ENSG00000132386

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000254722 ENSG00000132386 No_inf pgKDN_inf SERPINF1 protein_coding protein_coding 45.88986 80.93271 32.64677 3.46131 1.639116 -1.309519 21.723411 49.603038 8.056622 3.212757 3.132022 -2.6206828 0.3915500 0.611950 0.256475 -0.355475 0.23685897 0.01092449 FALSE TRUE
ENST00000572048 ENSG00000132386 No_inf pgKDN_inf SERPINF1 protein_coding protein_coding 45.88986 80.93271 32.64677 3.46131 1.639116 -1.309519 7.400868 3.330432 10.152183 1.565370 1.310387 1.6051037 0.2392250 0.040450 0.308550 0.268100 0.01092449 0.01092449 FALSE FALSE
ENST00000572517 ENSG00000132386 No_inf pgKDN_inf SERPINF1 protein_coding retained_intron 45.88986 80.93271 32.64677 3.46131 1.639116 -1.309519 4.656139 4.366549 6.648961 2.039099 2.674859 0.6055034 0.1191000 0.052725 0.199375 0.146650 0.68735600 0.01092449 FALSE TRUE
MSTRG.11869.1 ENSG00000132386 No_inf pgKDN_inf SERPINF1 protein_coding   45.88986 80.93271 32.64677 3.46131 1.639116 -1.309519 7.972525 17.814962 4.056447 3.488714 1.893985 -2.1320583 0.1470417 0.225225 0.122250 -0.102975 0.64447215 0.01092449 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132386 E001 4.7814069 0.0039553768 3.804743e-01 6.670098e-01 17 1762029 1762059 31 + 0.555 0.683 0.563
ENSG00000132386 E002 4.5271343 0.0034575759 4.633889e-01 7.333050e-01 17 1762060 1762060 1 + 0.555 0.662 0.472
ENSG00000132386 E003 4.6542706 0.0035179928 4.200373e-01 6.994440e-01 17 1762061 1762067 7 + 0.555 0.673 0.518
ENSG00000132386 E004 11.9446029 0.0011956985 2.086269e-01 4.926841e-01 17 1762068 1762111 44 + 0.888 1.021 0.497
ENSG00000132386 E005 8.0515790 0.0017158354 1.948753e-01 4.749178e-01 17 1762112 1762113 2 + 0.711 0.874 0.647
ENSG00000132386 E006 0.0000000       17 1762114 1762273 160 +      
ENSG00000132386 E007 0.0000000       17 1762339 1762388 50 +      
ENSG00000132386 E008 0.1187032 0.0118712103 8.649114e-02   17 1762829 1762883 55 + 0.181 0.000 -12.971
ENSG00000132386 E009 0.0000000       17 1766274 1766661 388 +      
ENSG00000132386 E010 17.6558821 0.0007832403 8.394968e-01 9.424157e-01 17 1766903 1766994 92 + 1.175 1.152 -0.082
ENSG00000132386 E011 0.1268540 0.0123680687 1.000000e+00   17 1769672 1769851 180 + 0.000 0.048 9.031
ENSG00000132386 E012 12.0353812 0.0011115708 8.417486e-01 9.432106e-01 17 1769852 1769890 39 + 0.991 1.006 0.056
ENSG00000132386 E013 42.3574085 0.0004962941 8.272606e-01 9.374822e-01 17 1769891 1770050 160 + 1.513 1.519 0.023
ENSG00000132386 E014 0.0000000       17 1770526 1770833 308 +      
ENSG00000132386 E015 0.6342667 0.0143570752 4.408152e-01 7.164576e-01 17 1770834 1771028 195 + 0.000 0.198 11.224
ENSG00000132386 E016 48.7727856 0.0003134819 5.888866e-01 8.177186e-01 17 1771029 1771184 156 + 1.559 1.582 0.079
ENSG00000132386 E017 3.9557382 0.0746469130 3.410837e-09 2.646907e-07 17 1771719 1771871 153 + 1.160 0.258 -4.053
ENSG00000132386 E018 69.4537637 0.0002818194 6.870125e-01 8.709209e-01 17 1771872 1772075 204 + 1.718 1.730 0.040
ENSG00000132386 E019 21.2905978 0.0007057244 7.540130e-01 9.031879e-01 17 1775058 1775062 5 + 1.257 1.227 -0.106
ENSG00000132386 E020 57.0263870 0.0002883723 6.888726e-01 8.718877e-01 17 1775063 1775200 138 + 1.633 1.646 0.047
ENSG00000132386 E021 1.1140491 0.0110994129 2.925068e-01 5.860469e-01 17 1776450 1776531 82 + 0.407 0.229 -1.160
ENSG00000132386 E022 78.6994480 0.0002069219 8.130672e-01 9.314549e-01 17 1776532 1776742 211 + 1.778 1.782 0.013
ENSG00000132386 E023 97.3132325 0.0001884149 5.852939e-01 8.157964e-01 17 1777187 1777643 457 + 1.893 1.868 -0.084

Help

Please Click HERE to learn more details about the results from DEXseq.