ENSG00000132463

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000502323 ENSG00000132463 No_inf pgKDN_inf GRSF1 protein_coding protein_coding 55.96733 49.0773 67.77664 2.498428 3.234669 0.4656509 1.533529 4.600587 0.000000 1.845752 0.0000000 -8.8488066 0.03330833 0.099925 0.000000 -0.099925 0.01822494 0.01822494 FALSE  
ENST00000505068 ENSG00000132463 No_inf pgKDN_inf GRSF1 protein_coding retained_intron 55.96733 49.0773 67.77664 2.498428 3.234669 0.4656509 4.876711 5.284745 4.925209 0.314825 0.3788629 -0.1014500 0.09010833 0.109250 0.073000 -0.036250 0.70033157 0.01822494 TRUE  
ENST00000506453 ENSG00000132463 No_inf pgKDN_inf GRSF1 protein_coding nonsense_mediated_decay 55.96733 49.0773 67.77664 2.498428 3.234669 0.4656509 19.908094 19.015016 27.641991 4.424506 4.6632863 0.5394857 0.33895000 0.377800 0.400475 0.022675 0.95770909 0.01822494 FALSE  
ENST00000514161 ENSG00000132463 No_inf pgKDN_inf GRSF1 protein_coding protein_coding 55.96733 49.0773 67.77664 2.498428 3.234669 0.4656509 7.617369 1.789619 9.298169 1.789619 3.5310937 2.3708059 0.13989167 0.035850 0.144450 0.108600 0.28539783 0.01822494 FALSE  
MSTRG.21856.2 ENSG00000132463 No_inf pgKDN_inf GRSF1 protein_coding   55.96733 49.0773 67.77664 2.498428 3.234669 0.4656509 20.107456 15.396112 24.871565 1.347412 1.9308963 0.6915744 0.35952500 0.312050 0.366850 0.054800 0.76882571 0.01822494 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132463 E001 19.5436562 0.0086086524 0.0373856607 0.186251452 4 70815783 70819530 3748 - 1.230 1.387 0.547
ENSG00000132463 E002 16.4434077 0.0021871426 0.2033599285 0.485847813 4 70819531 70819757 227 - 1.193 1.287 0.330
ENSG00000132463 E003 93.2061936 0.0004548812 0.3059804125 0.599258873 4 70819758 70820311 554 - 1.958 1.990 0.110
ENSG00000132463 E004 23.7705110 0.0015776928 0.0047359611 0.047650706 4 70820312 70820374 63 - 1.300 1.475 0.607
ENSG00000132463 E005 61.1274886 0.0035601600 0.1534789556 0.418109607 4 70820375 70820698 324 - 1.761 1.825 0.218
ENSG00000132463 E006 26.7869295 0.0005560292 0.2439312398 0.533946990 4 70820699 70820745 47 - 1.474 1.409 -0.222
ENSG00000132463 E007 49.4645694 0.0006631757 0.9848961502 0.998995064 4 70820746 70820861 116 - 1.702 1.704 0.008
ENSG00000132463 E008 37.5489121 0.0003767138 0.5748410748 0.809617134 4 70824294 70824368 75 - 1.572 1.600 0.097
ENSG00000132463 E009 63.5773616 0.0002306322 0.6163442223 0.833690711 4 70825296 70825431 136 - 1.800 1.820 0.067
ENSG00000132463 E010 17.0687417 0.0007898620 0.0844084355 0.300049237 4 70825432 70826123 692 - 1.193 1.316 0.430
ENSG00000132463 E011 59.1026252 0.0042906062 0.7718730088 0.912185763 4 70826124 70826245 122 - 1.784 1.773 -0.038
ENSG00000132463 E012 72.9550607 0.0002233792 0.3590564559 0.648529995 4 70827852 70828036 185 - 1.883 1.853 -0.099
ENSG00000132463 E013 70.8324701 0.0002715634 0.7035876315 0.879427470 4 70831539 70831674 136 - 1.861 1.850 -0.039
ENSG00000132463 E014 66.5534759 0.0004547884 0.1471346333 0.408284078 4 70832307 70832450 144 - 1.853 1.802 -0.171
ENSG00000132463 E015 52.6025769 0.0005517913 0.1099792793 0.348075923 4 70833118 70833273 156 - 1.759 1.695 -0.216
ENSG00000132463 E016 33.5376812 0.0022276969 0.6305950118 0.841499629 4 70836158 70836314 157 - 1.550 1.526 -0.083
ENSG00000132463 E017 0.5073513 0.0157964664 0.0326433016 0.171246360 4 70838869 70839176 308 - 0.000 0.312 10.650
ENSG00000132463 E018 0.3631878 0.0165462426 0.6702900376   4 70839177 70839227 51 - 0.163 0.101 -0.799
ENSG00000132463 E019 0.4907673 0.1080684894 0.8945001503   4 70839228 70839470 243 - 0.163 0.183 0.200
ENSG00000132463 E020 36.4829852 0.0003957796 0.0001406997 0.003138337 4 70839471 70839897 427 - 1.654 1.467 -0.637

Help

Please Click HERE to learn more details about the results from DEXseq.