ENSG00000132589

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000394908 ENSG00000132589 No_inf pgKDN_inf FLOT2 protein_coding protein_coding 46.11151 65.9093 33.01391 15.82296 0.2829564 -0.99719 27.810368 26.879889 30.02372 8.178731 1.988621 0.1595192 0.7425833 0.548075 0.909925 0.361850 0.4476421 0.0471867 FALSE  
ENST00000584569 ENSG00000132589 No_inf pgKDN_inf FLOT2 protein_coding protein_coding_CDS_not_defined 46.11151 65.9093 33.01391 15.82296 0.2829564 -0.99719 10.839471 23.413924 0.00000 16.607111 0.000000 -11.1937671 0.1275083 0.246875 0.000000 -0.246875 0.8138070 0.0471867    
MSTRG.12335.5 ENSG00000132589 No_inf pgKDN_inf FLOT2 protein_coding   46.11151 65.9093 33.01391 15.82296 0.2829564 -0.99719 2.694631 6.100501 0.00000 3.317498 0.000000 -9.2551468 0.0429750 0.073500 0.000000 -0.073500 0.0471867 0.0471867 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132589 E001 0.0000000       17 28879335 28879338 4 -      
ENSG00000132589 E002 0.3641952 1.666793e-02 3.962421e-01   17 28879339 28879340 2 - 0.199 0.081 -1.494
ENSG00000132589 E003 21.2205565 1.097481e-02 2.803152e-02 1.564255e-01 17 28879341 28879519 179 - 1.230 1.397 0.583
ENSG00000132589 E004 247.6308507 9.947076e-05 7.465390e-08 4.473759e-06 17 28879520 28880577 1058 - 2.334 2.418 0.281
ENSG00000132589 E005 21.3512162 6.826176e-04 5.240807e-01 7.772154e-01 17 28880578 28880599 22 - 1.317 1.355 0.133
ENSG00000132589 E006 49.7679068 3.819348e-04 9.701858e-01 9.939784e-01 17 28880713 28880862 150 - 1.697 1.696 -0.003
ENSG00000132589 E007 45.6614727 3.379245e-04 6.375858e-01 8.454223e-01 17 28881192 28881343 152 - 1.674 1.651 -0.079
ENSG00000132589 E008 19.6766350 7.004776e-04 5.951154e-01 8.219872e-01 17 28881344 28881375 32 - 1.329 1.291 -0.131
ENSG00000132589 E009 0.1272623 1.244272e-02 7.535743e-01   17 28881775 28881813 39 - 0.000 0.081 8.827
ENSG00000132589 E010 50.8780981 3.183036e-04 1.412103e-01 3.997919e-01 17 28881814 28882024 211 - 1.743 1.680 -0.214
ENSG00000132589 E011 11.0871593 1.269822e-03 9.162901e-01 9.737077e-01 17 28882025 28882028 4 - 1.081 1.069 -0.041
ENSG00000132589 E012 32.4568410 4.240480e-04 3.154681e-01 6.083545e-01 17 28882118 28882237 120 - 1.547 1.493 -0.187
ENSG00000132589 E013 32.4588420 6.147342e-03 2.848544e-01 5.786095e-01 17 28882337 28882450 114 - 1.555 1.487 -0.231
ENSG00000132589 E014 24.9242618 2.816312e-03 1.233507e-01 3.717685e-01 17 28882573 28882632 60 - 1.461 1.363 -0.337
ENSG00000132589 E015 24.5871575 1.085130e-02 4.338789e-01 7.111632e-01 17 28882633 28882691 59 - 1.434 1.375 -0.204
ENSG00000132589 E016 1.1335583 1.071149e-02 4.583916e-02 2.097471e-01 17 28882692 28882737 46 - 0.111 0.423 2.506
ENSG00000132589 E017 2.6289178 1.256752e-01 8.296334e-02 2.968386e-01 17 28882740 28882978 239 - 0.335 0.654 1.595
ENSG00000132589 E018 0.6154116 2.116466e-01 9.409817e-01 9.833351e-01 17 28882979 28883107 129 - 0.199 0.209 0.091
ENSG00000132589 E019 23.3450382 6.123657e-04 2.875364e-03 3.345845e-02 17 28883108 28883176 69 - 1.478 1.296 -0.630
ENSG00000132589 E020 21.6543634 7.532702e-04 1.396792e-02 9.987346e-02 17 28883177 28883231 55 - 1.434 1.278 -0.543
ENSG00000132589 E021 22.0077451 3.739019e-02 7.450483e-02 2.782995e-01 17 28884225 28884315 91 - 1.447 1.277 -0.591
ENSG00000132589 E022 0.4991354 1.523159e-02 5.069389e-01   17 28885612 28885685 74 - 0.111 0.209 1.091
ENSG00000132589 E023 1.8866194 9.486305e-03 1.809431e-02 1.186738e-01 17 28885857 28885947 91 - 0.199 0.566 2.207
ENSG00000132589 E024 1.0059188 2.606632e-02 7.884146e-02 2.878383e-01 17 28885948 28886011 64 - 0.111 0.388 2.313
ENSG00000132589 E025 11.7309214 1.131793e-02 6.264352e-02 2.514599e-01 17 28888945 28889026 82 - 1.191 1.021 -0.614
ENSG00000132589 E026 0.1170040 1.171017e-02 3.814460e-01   17 28897490 28897525 36 - 0.111 0.000 -10.377
ENSG00000132589 E027 8.4288869 1.136449e-02 1.034592e-01 3.362034e-01 17 28897526 28897733 208 - 1.059 0.892 -0.619

Help

Please Click HERE to learn more details about the results from DEXseq.