ENSG00000132640

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000254977 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 1.9002324 0.9294988 2.1207137 0.6037188 1.3746878 1.1813736 0.28080833 0.086275 0.324675 0.238400 0.790352253 0.002850229 FALSE TRUE
ENST00000378226 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 0.4836371 1.2779114 0.1730000 0.7525374 0.1000598 -2.8151175 0.04792500 0.118625 0.025150 -0.093475 0.858350146 0.002850229 FALSE TRUE
ENST00000399006 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 0.4080704 0.6762283 0.0000000 0.4463834 0.0000000 -6.1006168 0.05213333 0.062300 0.000000 -0.062300 0.663682782 0.002850229 FALSE TRUE
ENST00000405977 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 0.4734379 0.9216944 0.1990001 0.2198113 0.1319828 -2.1563530 0.05600833 0.085375 0.032475 -0.052900 0.555486378 0.002850229 FALSE TRUE
ENST00000422390 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 0.5623039 0.0000000 1.6869118 0.0000000 0.9823446 7.4067678 0.08966667 0.000000 0.269000 0.269000 0.418460494 0.002850229 FALSE TRUE
ENST00000430557 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 1.1180979 1.6231122 0.1386578 0.6521977 0.1386578 -3.4575565 0.14545833 0.151175 0.018900 -0.132275 0.260363607 0.002850229 FALSE TRUE
ENST00000449299 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding nonsense_mediated_decay 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 1.2502326 1.2544855 2.2460509 0.7279300 1.1199124 0.8352491 0.16098333 0.116300 0.329775 0.213475 0.722275569 0.002850229 FALSE TRUE
ENST00000455911 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 0.3900963 1.1702890 0.0000000 1.1702890 0.0000000 -6.8829963 0.03573333 0.107200 0.000000 -0.107200 0.928752960 0.002850229 FALSE TRUE
ENST00000473416 ENSG00000132640 No_inf pgKDN_inf BTBD3 protein_coding protein_coding_CDS_not_defined 7.815063 10.80867 6.564334 0.09513452 0.279308 -0.7186058 0.9436181 2.2268876 0.0000000 0.5662499 0.0000000 -7.8053490 0.10256667 0.205425 0.000000 -0.205425 0.002850229 0.002850229 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132640 E001 0.0000000       20 11890723 11890816 94 +      
ENSG00000132640 E002 0.1170040 0.0116737120 0.2637905955   20 11890817 11890827 11 + 0.126 0.000 -11.232
ENSG00000132640 E003 0.4797798 0.0157512356 0.0985348854   20 11890828 11890869 42 + 0.303 0.071 -2.501
ENSG00000132640 E004 0.9791063 0.0117094602 0.3569604231 0.64670835 20 11890870 11890954 85 + 0.370 0.234 -0.916
ENSG00000132640 E005 0.0000000       20 11891327 11891447 121 +      
ENSG00000132640 E006 0.0000000       20 11892493 11892543 51 +      
ENSG00000132640 E007 1.8951557 0.0197430568 0.0133807317 0.09709086 20 11917778 11917864 87 + 0.126 0.543 2.891
ENSG00000132640 E008 1.0148286 0.0141898535 0.0240408620 0.14198640 20 11917865 11917892 28 + 0.000 0.385 13.604
ENSG00000132640 E009 1.2609801 0.0118463829 0.0811056334 0.29261025 20 11917893 11918011 119 + 0.126 0.416 2.254
ENSG00000132640 E010 2.1233966 0.1901837733 0.5610791048 0.80154300 20 11918012 11918333 322 + 0.370 0.521 0.786
ENSG00000132640 E011 0.0000000       20 11918334 11918601 268 +      
ENSG00000132640 E012 0.6256726 0.0152115468 0.5110352598 0.76836965 20 11918810 11918850 41 + 0.126 0.234 1.084
ENSG00000132640 E013 0.5079160 0.2126783299 0.2391774816 0.52812261 20 11918851 11918876 26 + 0.000 0.234 12.524
ENSG00000132640 E014 1.2585573 0.0154510830 0.0818071472 0.29423969 20 11918877 11919085 209 + 0.126 0.416 2.254
ENSG00000132640 E015 3.3462315 0.0047962031 0.9411880845 0.98341173 20 11919086 11919176 91 + 0.605 0.624 0.084
ENSG00000132640 E016 0.7520260 0.0133982302 0.3548738633 0.64459696 20 11919277 11919423 147 + 0.126 0.277 1.406
ENSG00000132640 E017 0.3810317 0.0178632716 0.3096583236   20 11919424 11919540 117 + 0.000 0.186 12.371
ENSG00000132640 E018 0.8884444 0.0392707984 0.0419145533 0.19920246 20 11919541 11919610 70 + 0.000 0.352 13.396
ENSG00000132640 E019 0.8886653 0.0121990849 0.0382550015 0.18883052 20 11919611 11919717 107 + 0.000 0.352 13.447
ENSG00000132640 E020 7.4524139 0.0218408578 0.7253279409 0.88977476 20 11919718 11919836 119 + 0.869 0.919 0.193
ENSG00000132640 E021 0.1265070 0.0122974188 1.0000000000   20 11921566 11921662 97 + 0.000 0.071 10.914
ENSG00000132640 E022 182.0440965 0.0001387836 0.0006209205 0.01029789 20 11922634 11926609 3976 + 2.246 2.231 -0.050

Help

Please Click HERE to learn more details about the results from DEXseq.