ENSG00000132680

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368320 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding protein_coding 36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 5.463598 5.739788 4.668496 3.3162340 1.6331900 -0.29746391 0.15312500 0.136225 0.137625 0.001400 0.8420852672 0.0008524111 FALSE  
ENST00000368321 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding protein_coding 36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 7.335308 4.354688 9.107154 3.0456709 3.1267696 1.06270490 0.21099167 0.098825 0.270375 0.171550 0.6112037511 0.0008524111 FALSE  
ENST00000465953 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding protein_coding_CDS_not_defined 36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 4.459213 6.624928 4.416746 0.8301631 0.8849268 -0.58383416 0.11964167 0.153675 0.132850 -0.020825 0.8877087661 0.0008524111    
ENST00000483237 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding protein_coding_CDS_not_defined 36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 1.333708 2.906273 0.000000 0.8261142 0.0000000 -8.18798183 0.03404167 0.068250 0.000000 -0.068250 0.0008524111 0.0008524111 FALSE  
MSTRG.1975.1 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding   36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 4.113638 5.139988 5.347290 4.7499520 2.1312913 0.05693423 0.11292500 0.118400 0.163225 0.044825 0.5146454501 0.0008524111 TRUE  
MSTRG.1975.2 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding   36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 3.079477 6.315909 1.290512 3.6503306 1.2905123 -2.28219282 0.07928333 0.143650 0.043225 -0.100425 0.8469239737 0.0008524111 FALSE  
MSTRG.1975.3 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding   36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 3.034064 3.004536 3.450763 2.1882468 2.0659261 0.19915385 0.08457500 0.068800 0.103175 0.034375 0.9708789179 0.0008524111 TRUE  
MSTRG.1975.4 ENSG00000132680 No_inf pgKDN_inf KHDC4 protein_coding   36.09969 43.07968 32.98354 0.6597345 1.428919 -0.3851589 6.136430 7.311479 3.974900 4.2412548 2.8634323 -0.87759176 0.17465000 0.173200 0.128000 -0.045200 1.0000000000 0.0008524111 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132680 E001 0.1176306 0.0117686297 3.939997e-01   1 155913044 155913044 1 - 0.109 0.000 -9.755
ENSG00000132680 E002 205.0359240 0.0001092181 5.962455e-01 8.224988e-01 1 155913045 155914111 1067 - 2.300 2.310 0.035
ENSG00000132680 E003 57.5172924 0.0003525750 2.363906e-01 5.254313e-01 1 155914112 155914320 209 - 1.786 1.741 -0.153
ENSG00000132680 E004 68.9278847 0.0002452590 5.374798e-09 4.002163e-07 1 155914321 155915576 1256 - 1.696 1.913 0.730
ENSG00000132680 E005 5.8415125 0.0023846223 7.607304e-02 2.819104e-01 1 155915577 155915663 87 - 0.698 0.900 0.800
ENSG00000132680 E006 10.1926579 0.0014911566 2.682412e-02 1.520156e-01 1 155915664 155915872 209 - 0.910 1.114 0.752
ENSG00000132680 E007 21.0658699 0.0070346676 9.571718e-01 9.898045e-01 1 155915873 155915964 92 - 1.333 1.339 0.022
ENSG00000132680 E008 21.4117842 0.0010609860 7.390219e-01 8.965205e-01 1 155916625 155916709 85 - 1.355 1.335 -0.071
ENSG00000132680 E009 9.9349727 0.0013969306 3.033010e-01 5.966457e-01 1 155916710 155916737 28 - 1.083 0.993 -0.331
ENSG00000132680 E010 7.4103139 0.0018646089 5.213733e-01 7.753550e-01 1 155916738 155916942 205 - 0.878 0.944 0.248
ENSG00000132680 E011 30.0640474 0.0004784167 9.086138e-02 3.130628e-01 1 155917499 155917672 174 - 1.536 1.446 -0.308
ENSG00000132680 E012 1.0144816 0.0123856241 7.143113e-03 6.387940e-02 1 155921239 155921374 136 - 0.000 0.429 13.642
ENSG00000132680 E013 10.3187110 0.0017528705 4.664112e-01 7.351088e-01 1 155921375 155921384 10 - 1.083 1.020 -0.231
ENSG00000132680 E014 14.5199293 0.0010725883 7.223165e-01 8.883435e-01 1 155921385 155921421 37 - 1.199 1.173 -0.094
ENSG00000132680 E015 21.3587012 0.0006671373 2.727759e-01 5.665176e-01 1 155921422 155921524 103 - 1.382 1.313 -0.238
ENSG00000132680 E016 9.3216796 0.0617321615 6.844034e-01 8.693877e-01 1 155921525 155921527 3 - 1.040 0.983 -0.208
ENSG00000132680 E017 17.9211954 0.0239798525 5.169763e-01 7.725851e-01 1 155921528 155921628 101 - 1.303 1.246 -0.200
ENSG00000132680 E018 18.4122023 0.0007583375 2.275616e-01 5.160011e-01 1 155921861 155921918 58 - 1.327 1.246 -0.283
ENSG00000132680 E019 0.5081066 0.0159960414 8.833552e-02 3.082883e-01 1 155921919 155922014 96 - 0.000 0.265 12.692
ENSG00000132680 E020 19.7219389 0.0007098571 4.423674e-02 2.056957e-01 1 155923627 155923687 61 - 1.382 1.251 -0.455
ENSG00000132680 E021 39.2325848 0.0010638942 5.235476e-01 7.767524e-01 1 155925632 155925843 212 - 1.614 1.585 -0.101
ENSG00000132680 E022 1.4952693 0.0315909502 2.282393e-01 5.167886e-01 1 155926471 155926675 205 - 0.268 0.461 1.147
ENSG00000132680 E023 31.9134571 0.0009057304 9.089707e-01 9.711391e-01 1 155926676 155926839 164 - 1.506 1.513 0.023
ENSG00000132680 E024 19.2771550 0.0017729339 3.123627e-01 6.058100e-01 1 155927104 155927156 53 - 1.338 1.271 -0.235
ENSG00000132680 E025 18.0226572 0.0009082074 1.529928e-01 4.172700e-01 1 155929296 155929375 80 - 1.327 1.230 -0.339
ENSG00000132680 E026 19.6687405 0.0010567991 5.140824e-01 7.708449e-01 1 155929712 155929840 129 - 1.333 1.290 -0.148
ENSG00000132680 E027 0.2441403 0.0162914930 8.125721e-01   1 155932273 155932714 442 - 0.109 0.083 -0.437
ENSG00000132680 E028 0.0000000       1 155933584 155933632 49 -      
ENSG00000132680 E029 24.2249603 0.0005872625 5.245872e-01 7.776671e-01 1 155933633 155933849 217 - 1.416 1.379 -0.129
ENSG00000132680 E030 8.3934482 0.0019780495 6.527855e-01 8.538216e-01 1 155934336 155934413 78 - 0.939 0.983 0.165

Help

Please Click HERE to learn more details about the results from DEXseq.