ENSG00000132768

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000255108 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding protein_coding 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 10.8670486 3.924251 14.469367 1.3302305 1.2160635 1.8798376 0.28490833 0.123100 0.381425 0.258325 0.2134300 0.0232993 FALSE TRUE
ENST00000459879 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding protein_coding 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 10.2016466 9.254173 11.520000 0.9393575 1.2042738 0.3156585 0.27290833 0.288650 0.300250 0.011600 0.9872729 0.0232993 FALSE TRUE
ENST00000490861 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding retained_intron 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 4.1821264 4.186187 3.869697 0.4247622 0.1496837 -0.1131350 0.11295000 0.131200 0.101800 -0.029400 0.8349896 0.0232993 FALSE TRUE
ENST00000495421 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding nonsense_mediated_decay 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 1.2279297 3.683789 0.000000 1.4073873 0.0000000 -8.5289577 0.03950833 0.118525 0.000000 -0.118525 0.0232993 0.0232993 FALSE TRUE
ENST00000527567 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding retained_intron 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 3.5282424 3.939576 2.486516 2.3506121 1.4359035 -0.6617813 0.09507500 0.122900 0.064225 -0.058675 0.9884288 0.0232993 FALSE TRUE
ENST00000534655 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding retained_intron 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 0.8661937 1.829479 0.000000 1.0575170 0.0000000 -7.5231533 0.02399167 0.055275 0.000000 -0.055275 0.4527449 0.0232993   FALSE
ENST00000534786 ENSG00000132768 No_inf pgKDN_inf DPH2 protein_coding retained_intron 37.37773 31.92841 38.11996 0.935602 1.432063 0.2556323 1.4901513 2.910917 1.559537 1.6886385 0.9176970 -0.8960817 0.04495833 0.092550 0.042325 -0.050225 0.9670624 0.0232993 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000132768 E001 0.0000000       1 43970000 43970007 8 +      
ENSG00000132768 E002 0.0000000       1 43970008 43970009 2 +      
ENSG00000132768 E003 0.0000000       1 43970010 43970022 13 +      
ENSG00000132768 E004 0.0000000       1 43970023 43970023 1 +      
ENSG00000132768 E005 0.0000000       1 43970024 43970024 1 +      
ENSG00000132768 E006 0.0000000       1 43970025 43970028 4 +      
ENSG00000132768 E007 0.0000000       1 43970029 43970066 38 +      
ENSG00000132768 E008 0.0000000       1 43970067 43970104 38 +      
ENSG00000132768 E009 0.0000000       1 43970105 43970270 166 +      
ENSG00000132768 E010 0.1170040 0.0117830363 0.62715992   1 43970271 43970312 42 + 0.089 0.000 -8.973
ENSG00000132768 E011 0.3700180 0.1506708775 0.52757876   1 43970313 43970314 2 + 0.089 0.185 1.228
ENSG00000132768 E012 1.8240278 0.0078464589 0.63635106 0.84488564 1 43970315 43970322 8 + 0.482 0.413 -0.357
ENSG00000132768 E013 14.6805640 0.0011161166 0.62455747 0.83849557 1 43970596 43970708 113 + 1.177 1.214 0.132
ENSG00000132768 E014 7.4354045 0.0123697024 0.00294614 0.03407616 1 43970709 43970817 109 + 0.742 1.064 1.228
ENSG00000132768 E015 5.5505718 0.0075186608 0.07095002 0.26980319 1 43970818 43970869 52 + 0.705 0.911 0.813
ENSG00000132768 E016 4.5625973 0.0129316258 0.12129194 0.36865369 1 43970870 43970905 36 + 0.643 0.834 0.781
ENSG00000132768 E017 4.3329660 0.0153445525 0.02709686 0.15299853 1 43970906 43970965 60 + 0.570 0.851 1.167
ENSG00000132768 E018 24.8961344 0.0011051236 0.65977908 0.85799597 1 43970966 43971113 148 + 1.424 1.400 -0.084
ENSG00000132768 E019 15.2480019 0.0008919162 0.76424794 0.90822643 1 43971114 43971189 76 + 1.220 1.200 -0.073
ENSG00000132768 E020 2.8238393 0.0075764185 0.56649329 0.80469535 1 43971190 43971220 31 + 0.543 0.621 0.354
ENSG00000132768 E021 5.8028273 0.0024833661 0.03294933 0.17223192 1 43971221 43971386 166 + 0.705 0.939 0.916
ENSG00000132768 E022 11.1185322 0.0012263512 0.82794425 0.93773864 1 43971387 43971468 82 + 1.074 1.093 0.069
ENSG00000132768 E023 9.6696108 0.0015890501 0.56318455 0.80267150 1 43971469 43971540 72 + 1.002 1.054 0.192
ENSG00000132768 E024 10.6647468 0.0016104440 0.29533560 0.58859767 1 43971541 43971659 119 + 1.021 1.111 0.328
ENSG00000132768 E025 31.4249897 0.0005536872 0.19404387 0.47389794 1 43971660 43971920 261 + 1.540 1.475 -0.223
ENSG00000132768 E026 25.7378106 0.0006352772 0.01127048 0.08703376 1 43971921 43972070 150 + 1.489 1.346 -0.494
ENSG00000132768 E027 25.7412919 0.0009247834 0.74398718 0.89873493 1 43972158 43972334 177 + 1.435 1.418 -0.060
ENSG00000132768 E028 0.8612538 0.0144549690 0.56487644 0.80400194 1 43972335 43972414 80 + 0.225 0.314 0.643
ENSG00000132768 E029 110.3935880 0.0002189432 0.20920194 0.49344431 1 43972415 43973369 955 + 2.060 2.031 -0.095

Help

Please Click HERE to learn more details about the results from DEXseq.