ENSG00000133030

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341712 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 7.080823 5.723673 9.295546 2.0039973 1.7028947 0.69863110 0.20293333 0.128975 0.227100 0.098125 7.664683e-01 3.050389e-06 FALSE TRUE
ENST00000395811 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 1.856995 4.979597 0.000000 1.0296939 0.0000000 -8.96277951 0.04565000 0.113300 0.000000 -0.113300 3.050389e-06 3.050389e-06 FALSE TRUE
ENST00000429184 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 6.487695 10.313816 5.319602 3.7403704 1.9293393 -0.95387658 0.17551667 0.231050 0.147025 -0.084025 8.893190e-01 3.050389e-06 FALSE TRUE
ENST00000462033 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 2.997952 1.360716 6.341944 1.3607161 2.4278601 2.21226839 0.07086667 0.028025 0.139275 0.111250 2.595364e-01 3.050389e-06   FALSE
ENST00000581855 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding_CDS_not_defined 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 1.851622 0.000000 5.554866 0.0000000 5.5548656 9.12020302 0.03020833 0.000000 0.090625 0.090625 8.342481e-01 3.050389e-06   FALSE
ENST00000581989 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding_CDS_not_defined 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 1.911539 4.130407 1.099048 0.9038222 0.6346632 -1.90045055 0.04393333 0.088825 0.022775 -0.066050 2.904033e-01 3.050389e-06   FALSE
ENST00000651222 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding protein_coding 37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 3.336564 3.777500 3.719472 0.5002308 0.1370499 -0.02227447 0.09386667 0.084900 0.092200 0.007300 9.717352e-01 3.050389e-06 FALSE TRUE
MSTRG.12162.3 ENSG00000133030 No_inf pgKDN_inf MPRIP protein_coding   37.53792 45.25229 42.77194 2.747839 6.390004 -0.08130736 1.630242 0.000000 2.320580 0.0000000 1.0304759 7.86454513 0.05736667 0.000000 0.062225 0.062225 6.090884e-02 3.050389e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133030 E001 1.1083189 0.0160692112 7.344861e-01 8.946200e-01 17 17042457 17042493 37 + 0.350 0.294 -0.356
ENSG00000133030 E002 0.9803012 0.0167645310 5.279687e-01 7.798292e-01 17 17042494 17042494 1 + 0.350 0.249 -0.677
ENSG00000133030 E003 1.5801051 0.2111991970 2.501333e-01 5.410480e-01 17 17042495 17042544 50 + 0.541 0.294 -1.356
ENSG00000133030 E004 1.2084842 0.2258326037 1.403551e-01 3.986682e-01 17 17042545 17042548 4 + 0.501 0.199 -1.900
ENSG00000133030 E005 1.8252502 0.0860903669 1.586899e-01 4.257539e-01 17 17042549 17042596 48 + 0.578 0.335 -1.263
ENSG00000133030 E006 4.5057748 0.0034446945 2.955456e-02 1.615973e-01 17 17042597 17042759 163 + 0.875 0.612 -1.069
ENSG00000133030 E007 2.6987196 0.0255435241 5.505364e-01 7.948458e-01 17 17042760 17042806 47 + 0.612 0.521 -0.414
ENSG00000133030 E008 2.0979436 0.4754383246 7.977519e-01 9.238057e-01 17 17042807 17042848 42 + 0.455 0.495 0.200
ENSG00000133030 E009 8.9735234 0.0152327000 4.355412e-01 7.122678e-01 17 17042849 17042971 123 + 1.038 0.951 -0.319
ENSG00000133030 E010 0.4903851 0.0158825771 6.511906e-01   17 17057636 17057950 315 + 0.209 0.142 -0.677
ENSG00000133030 E011 10.8148134 0.0442542188 3.947210e-01 6.795263e-01 17 17075710 17075787 78 + 1.127 1.012 -0.414
ENSG00000133030 E012 8.3366452 0.0016230859 1.065653e-01 3.419120e-01 17 17078011 17078076 66 + 1.050 0.891 -0.592
ENSG00000133030 E013 2.4432535 0.0082319868 1.503158e-01 4.128919e-01 17 17096768 17097337 570 + 0.644 0.438 -0.967
ENSG00000133030 E014 13.1364825 0.0010627000 9.780480e-02 3.259797e-01 17 17126702 17126853 152 + 1.217 1.080 -0.488
ENSG00000133030 E015 6.4960307 0.0266368192 1.985929e-01 4.800285e-01 17 17131617 17131665 49 + 0.957 0.794 -0.623
ENSG00000133030 E016 10.2997306 0.0435649829 1.909427e-01 4.702969e-01 17 17131666 17131701 36 + 1.137 0.969 -0.610
ENSG00000133030 E017 11.4563056 0.0306449970 9.343848e-03 7.695084e-02 17 17136219 17136337 119 + 1.241 0.951 -1.048
ENSG00000133030 E018 12.1366712 0.0014714984 8.310578e-02 2.970920e-01 17 17136338 17136450 113 + 1.192 1.044 -0.531
ENSG00000133030 E019 16.6105050 0.0008269360 4.871547e-04 8.558373e-03 17 17137916 17138075 160 + 1.373 1.120 -0.890
ENSG00000133030 E020 2.8356173 0.0054858097 9.739721e-01 9.953877e-01 17 17138076 17138174 99 + 0.578 0.569 -0.040
ENSG00000133030 E021 4.3416435 0.0321751125 4.267465e-01 7.053246e-01 17 17138175 17138246 72 + 0.644 0.752 0.449
ENSG00000133030 E022 8.4311732 0.0073567019 4.232520e-01 7.025476e-01 17 17138247 17138429 183 + 0.910 0.987 0.291
ENSG00000133030 E023 0.7321333 0.0612719904 5.966051e-01 8.227231e-01 17 17141495 17141760 266 + 0.285 0.199 -0.677
ENSG00000133030 E024 0.3716209 0.0166550669 9.180197e-01   17 17142010 17142312 303 + 0.117 0.142 0.323
ENSG00000133030 E025 17.1197014 0.0065821725 4.203663e-01 6.997484e-01 17 17142627 17142765 139 + 1.285 1.217 -0.238
ENSG00000133030 E026 16.2718757 0.0008528583 6.203412e-01 8.358492e-01 17 17143556 17143669 114 + 1.248 1.207 -0.147
ENSG00000133030 E027 14.3209987 0.0010114345 9.985286e-01 1.000000e+00 17 17146036 17146092 57 + 1.174 1.169 -0.019
ENSG00000133030 E028 14.3838975 0.0010016312 2.157123e-01 5.015834e-01 17 17147319 17147387 69 + 1.233 1.133 -0.355
ENSG00000133030 E029 0.0000000       17 17149760 17150143 384 +      
ENSG00000133030 E030 17.9476434 0.0125786043 2.351933e-01 5.244301e-01 17 17150144 17150233 90 + 1.325 1.222 -0.360
ENSG00000133030 E031 16.5016976 0.0008636088 4.802935e-01 7.457430e-01 17 17154306 17154351 46 + 1.263 1.207 -0.199
ENSG00000133030 E032 19.5042392 0.0006665569 2.163041e-02 1.332817e-01 17 17154352 17154415 64 + 1.390 1.232 -0.550
ENSG00000133030 E033 17.4298642 0.0018856393 4.743661e-02 2.140601e-01 17 17158432 17158496 65 + 1.337 1.191 -0.514
ENSG00000133030 E034 58.1311284 0.0024377089 1.248141e-04 2.843989e-03 17 17158497 17159002 506 + 1.857 1.685 -0.580
ENSG00000133030 E035 13.5872717 0.0011443833 9.477961e-01 9.863664e-01 17 17161240 17161356 117 + 1.156 1.145 -0.037
ENSG00000133030 E036 32.2894564 0.0060648731 3.035406e-04 5.861496e-03 17 17164109 17165555 1447 + 1.634 1.411 -0.765
ENSG00000133030 E037 80.1668784 0.0014547158 1.966069e-04 4.121181e-03 17 17165556 17167915 2360 + 1.977 1.837 -0.469
ENSG00000133030 E038 0.3723465 0.0166777069 9.177784e-01   17 17170860 17171490 631 + 0.117 0.142 0.323
ENSG00000133030 E039 10.0007504 0.0017761755 8.961208e-01 9.658470e-01 17 17171718 17171719 2 + 1.038 1.021 -0.062
ENSG00000133030 E040 29.9010176 0.0292602655 3.177468e-01 6.104850e-01 17 17171720 17171865 146 + 1.533 1.437 -0.331
ENSG00000133030 E041 15.8191633 0.0143014807 5.720628e-02 2.390164e-01 17 17172698 17172720 23 + 1.312 1.139 -0.610
ENSG00000133030 E042 15.6231095 0.0010012466 2.269579e-01 5.151830e-01 17 17172721 17172815 95 + 1.263 1.169 -0.335
ENSG00000133030 E043 12.7421522 0.0019243269 6.965661e-01 8.760960e-01 17 17173916 17174075 160 + 1.106 1.133 0.097
ENSG00000133030 E044 9.3790754 0.0117244103 7.354287e-01 8.951119e-01 17 17175293 17175363 71 + 1.025 0.987 -0.139
ENSG00000133030 E045 14.1424942 0.0154784154 2.958478e-01 5.889439e-01 17 17175364 17175412 49 + 1.225 1.127 -0.349
ENSG00000133030 E046 35.9068745 0.0006125143 6.183437e-02 2.498117e-01 17 17176426 17176512 87 + 1.612 1.513 -0.340
ENSG00000133030 E047 17.3447588 0.0186881426 2.941744e-01 5.875480e-01 17 17177250 17177251 2 + 1.305 1.212 -0.327
ENSG00000133030 E048 48.9885091 0.0115911699 1.869576e-01 4.648610e-01 17 17177252 17177412 161 + 1.734 1.651 -0.283
ENSG00000133030 E049 0.2441403 0.0163849687 7.226001e-01   17 17179558 17179577 20 + 0.117 0.077 -0.677
ENSG00000133030 E050 36.7466441 0.0151501039 6.830148e-01 8.686671e-01 17 17180003 17180088 86 + 1.585 1.547 -0.128
ENSG00000133030 E051 1.2344165 0.0105662816 9.374694e-01 9.820871e-01 17 17180089 17180150 62 + 0.350 0.335 -0.092
ENSG00000133030 E052 8.0706132 0.0118526607 2.125493e-01 4.977234e-01 17 17180607 17180669 63 + 0.857 0.987 0.493
ENSG00000133030 E053 18.0459809 0.0524681576 7.246757e-01 8.894031e-01 17 17184823 17184861 39 + 1.256 1.270 0.049
ENSG00000133030 E054 152.6750505 0.0001570491 7.877777e-01 9.186397e-01 17 17184862 17186464 1603 + 2.170 2.171 0.003
ENSG00000133030 E055 8.7422765 0.0023604481 5.130936e-03 5.058159e-02 17 17186465 17186648 184 + 0.775 1.059 1.078
ENSG00000133030 E056 60.8442103 0.0062089620 3.563217e-05 9.988489e-04 17 17186649 17188327 1679 + 1.631 1.842 0.714
ENSG00000133030 E057 42.8133035 0.0006274710 1.391803e-09 1.158418e-07 17 17188328 17189240 913 + 1.411 1.715 1.040
ENSG00000133030 E058 200.1871255 0.0001138708 6.976583e-41 6.487500e-38 17 17189241 17192648 3408 + 2.081 2.374 0.981
ENSG00000133030 E059 0.0000000       17 17201458 17201633 176 +      
ENSG00000133030 E060 0.7526229 0.0450300780 2.575576e-01 5.498599e-01 17 17217490 17217679 190 + 0.117 0.294 1.644

Help

Please Click HERE to learn more details about the results from DEXseq.