ENSG00000133048

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000255409 ENSG00000133048 No_inf pgKDN_inf CHI3L1 protein_coding protein_coding 1953.282 1526.714 1745.362 9.582837 2.483941 0.1930959 1367.7422 1011.6431 1274.8506 6.958250 3.332674 0.3336249 0.6983583 0.662625 0.730425 0.067800 4.110438e-09 2.603442e-14 FALSE  
ENST00000404436 ENSG00000133048 No_inf pgKDN_inf CHI3L1 protein_coding protein_coding 1953.282 1526.714 1745.362 9.582837 2.483941 0.1930959 237.8793 130.3807 253.3430 8.149845 2.167954 0.9583076 0.1193417 0.085350 0.145175 0.059825 1.751850e-06 2.603442e-14 FALSE  
ENST00000472064 ENSG00000133048 No_inf pgKDN_inf CHI3L1 protein_coding retained_intron 1953.282 1526.714 1745.362 9.582837 2.483941 0.1930959 100.5692 105.5510 69.1569 3.568497 3.611631 -0.6099229 0.0526000 0.069125 0.039600 -0.029525 3.070920e-04 2.603442e-14 FALSE  
ENST00000478742 ENSG00000133048 No_inf pgKDN_inf CHI3L1 protein_coding retained_intron 1953.282 1526.714 1745.362 9.582837 2.483941 0.1930959 195.6423 216.2381 120.3205 1.553065 5.290724 -0.8456851 0.1024333 0.141600 0.068950 -0.072650 2.603442e-14 2.603442e-14 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133048 E001 254.86473 3.218619e-04 2.988604e-01 5.918174e-01 1 203178931 203178980 50 - 2.396 2.419 0.074
ENSG00000133048 E002 1221.75558 3.408159e-05 2.265473e-01 5.147493e-01 1 203178981 203179133 153 - 3.081 3.093 0.039
ENSG00000133048 E003 4307.81899 1.401330e-05 4.809090e-04 8.470720e-03 1 203179134 203179585 452 - 3.641 3.628 -0.044
ENSG00000133048 E004 83.04636 2.181871e-03 9.554311e-22 3.067275e-19 1 203179586 203179760 175 - 1.686 2.072 1.301
ENSG00000133048 E005 1439.11941 1.762848e-04 9.586535e-01 9.901969e-01 1 203179761 203179877 117 - 3.157 3.159 0.005
ENSG00000133048 E006 231.80600 3.942170e-04 1.306910e-41 1.305312e-38 1 203179878 203179997 120 - 2.188 2.488 1.001
ENSG00000133048 E007 514.34384 6.171433e-05 6.294890e-100 4.850123e-96 1 203179998 203180469 472 - 2.535 2.833 0.992
ENSG00000133048 E008 1338.96536 9.993214e-05 6.729171e-01 8.644716e-01 1 203180470 203180652 183 - 3.128 3.126 -0.009
ENSG00000133048 E009 1204.29620 3.164437e-05 6.306924e-05 1.608310e-03 1 203181162 203181285 124 - 3.098 3.064 -0.112
ENSG00000133048 E010 178.33109 1.589493e-03 1.298555e-48 1.945452e-45 1 203181286 203182134 849 - 1.978 2.415 1.461
ENSG00000133048 E011 1356.10458 2.991532e-05 4.448411e-03 4.565039e-02 1 203182731 203182852 122 - 3.144 3.122 -0.073
ENSG00000133048 E012 1202.68262 2.865573e-05 2.600605e-04 5.183335e-03 1 203183641 203183791 151 - 3.096 3.065 -0.102
ENSG00000133048 E013 683.83571 6.687014e-05 1.603615e-03 2.153084e-02 1 203184576 203184632 57 - 2.854 2.817 -0.120
ENSG00000133048 E014 1089.21663 8.501541e-05 2.067461e-08 1.388623e-06 1 203185184 203185385 202 - 3.064 3.011 -0.176
ENSG00000133048 E015 389.24074 2.612576e-04 1.384352e-07 7.826377e-06 1 203186316 203186345 30 - 2.633 2.547 -0.289
ENSG00000133048 E016 496.15188 6.633465e-05 2.900073e-07 1.523004e-05 1 203186599 203186704 106 - 2.731 2.661 -0.232

Help

Please Click HERE to learn more details about the results from DEXseq.