ENSG00000133063

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000255427 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding protein_coding 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.3221956 0.2955273 0.4076261 0.13755194 0.25865624 0.4509107 0.12144167 0.196400 0.087000 -0.109400 0.84241900 0.02239223 FALSE TRUE
ENST00000460619 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding protein_coding_CDS_not_defined 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.6001629 0.8858928 0.0000000 0.29529921 0.00000000 -6.4852542 0.23840833 0.458425 0.000000 -0.458425 0.02239223 0.02239223 FALSE FALSE
ENST00000479483 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding protein_coding_CDS_not_defined 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.6732378 0.2780222 1.2431032 0.16051789 0.46535595 2.1212532 0.23116667 0.239975 0.340925 0.100950 0.81494648 0.02239223 FALSE FALSE
ENST00000484834 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding protein_coding_CDS_not_defined 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.2439162 0.2011018 0.1210332 0.07032913 0.02254043 -0.6880072 0.11094167 0.105200 0.081550 -0.023650 0.83046673 0.02239223 TRUE TRUE
ENST00000491855 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding nonsense_mediated_decay 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.2651438 0.0000000 0.0000000 0.00000000 0.00000000 0.0000000 0.10384167 0.000000 0.000000 0.000000   0.02239223 TRUE TRUE
ENST00000503786 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding nonsense_mediated_decay 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.1425439 0.0000000 0.1219567 0.00000000 0.12195672 3.7219929 0.09593333 0.000000 0.195725 0.195725 0.94522536 0.02239223 TRUE TRUE
ENST00000506427 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding protein_coding_CDS_not_defined 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.2968987 0.0000000 0.8906962 0.00000000 0.89069618 6.4929686 0.04267500 0.000000 0.128025 0.128025 0.83695530 0.02239223 FALSE TRUE
ENST00000513472 ENSG00000133063 No_inf pgKDN_inf CHIT1 protein_coding protein_coding_CDS_not_defined 2.685004 1.660544 3.207132 0.288543 1.339439 0.945457 0.1409055 0.0000000 0.4227165 0.00000000 0.26442859 5.4353504 0.05559167 0.000000 0.166775 0.166775 0.63166259 0.02239223 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133063 E001 0.0000000       1 203212827 203212834 8 -      
ENSG00000133063 E002 0.9610716 0.013389605 0.28446508 0.57820518 1 203212835 203213045 211 - 0.378 0.181 -1.417
ENSG00000133063 E003 0.0000000       1 203216079 203216669 591 -      
ENSG00000133063 E004 0.6088063 0.018256451 0.90934238 0.97127087 1 203216670 203216947 278 - 0.229 0.181 -0.418
ENSG00000133063 E005 0.1187032 0.013001550 0.71192024   1 203216948 203217133 186 - 0.090 0.000 -11.017
ENSG00000133063 E006 0.0000000       1 203217302 203217372 71 -      
ENSG00000133063 E007 1.4432444 0.010379989 0.17777018 0.45247082 1 203217739 203217865 127 - 0.488 0.250 -1.417
ENSG00000133063 E008 0.2441403 0.018050608 0.82369926   1 203217866 203217934 69 - 0.090 0.100 0.168
ENSG00000133063 E009 0.2457744 0.018369179 0.82474842   1 203217935 203218091 157 - 0.090 0.100 0.167
ENSG00000133063 E010 0.7253671 0.015260773 0.63258899 0.84261790 1 203219216 203219329 114 - 0.284 0.182 -0.832
ENSG00000133063 E011 0.1176306 0.012372941 0.71255813   1 203219574 203219663 90 - 0.090 0.000 -11.017
ENSG00000133063 E012 0.8259403 0.013173772 0.01099410 0.08558829 1 203219664 203219849 186 - 0.418 0.000 -12.741
ENSG00000133063 E013 0.5973765 0.313024532 0.53759357 0.78668150 1 203222202 203222325 124 - 0.284 0.100 -1.832
ENSG00000133063 E014 0.6246996 0.019472389 0.09338416 0.31768521 1 203223135 203223259 125 - 0.090 0.309 2.168
ENSG00000133063 E015 0.4978456 0.018031622 0.20134981   1 203223495 203223587 93 - 0.090 0.250 1.752
ENSG00000133063 E016 0.4879983 0.137086810 0.81932776   1 203223588 203223660 73 - 0.165 0.182 0.168
ENSG00000133063 E017 0.4797824 0.023897171 0.47341958   1 203225048 203225104 57 - 0.229 0.100 -1.417
ENSG00000133063 E018 0.4902590 0.017281105 0.77907895   1 203225669 203225870 202 - 0.165 0.181 0.168
ENSG00000133063 E019 0.3634701 0.017788996 0.78790775   1 203228533 203228562 30 - 0.165 0.100 -0.832
ENSG00000133063 E020 0.2448930 0.018285202 0.81653646   1 203229612 203229673 62 - 0.090 0.100 0.168
ENSG00000133063 E021 0.1187032 0.013001550 0.71192024   1 203230015 203230084 70 - 0.090 0.000 -11.017
ENSG00000133063 E022 0.0000000       1 203240330 203240428 99 -      
ENSG00000133063 E023 0.0000000       1 203240463 203240520 58 -      
ENSG00000133063 E024 0.0000000       1 203240627 203240658 32 -      
ENSG00000133063 E025 0.1187032 0.013001550 0.71192024   1 203260802 203260862 61 - 0.090 0.000 -11.017
ENSG00000133063 E026 4.1977624 0.005453055 0.01084851 0.08482223 1 203268518 203272809 4292 - 0.602 0.809 0.859
ENSG00000133063 E027 0.6161394 0.016320448 0.44885205 0.72281101 1 203273376 203273641 266 - 0.165 0.250 0.752

Help

Please Click HERE to learn more details about the results from DEXseq.