ENSG00000133226

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323848 ENSG00000133226 No_inf pgKDN_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 41.10087 0.5666753 2.742372 -0.04005368 9.654082 5.284419 11.974209 3.1147504 4.5460050 1.1785905 0.22685000 0.127850 0.289300 0.161450 8.161494e-01 5.232543e-08 FALSE TRUE
ENST00000462710 ENSG00000133226 No_inf pgKDN_inf SRRM1 protein_coding retained_intron 42.85702 42.25822 41.10087 0.5666753 2.742372 -0.04005368 2.939645 4.180491 1.697369 0.3601322 0.5726565 -1.2953444 0.06830000 0.098700 0.041025 -0.057675 4.804642e-01 5.232543e-08   FALSE
ENST00000705662 ENSG00000133226 No_inf pgKDN_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 41.10087 0.5666753 2.742372 -0.04005368 14.199789 18.506609 9.328279 2.4028274 3.1314443 -0.9875913 0.33151667 0.436100 0.233050 -0.203050 3.686385e-01 5.232543e-08 FALSE TRUE
ENST00000705681 ENSG00000133226 No_inf pgKDN_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 41.10087 0.5666753 2.742372 -0.04005368 1.745408 0.000000 5.236223 0.0000000 3.0708206 9.0351353 0.04065000 0.000000 0.121950 0.121950 4.515004e-01 5.232543e-08 FALSE TRUE
ENST00000705682 ENSG00000133226 No_inf pgKDN_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 41.10087 0.5666753 2.742372 -0.04005368 4.049787 0.000000 4.552933 0.0000000 1.9412483 8.8338178 0.09337500 0.000000 0.113500 0.113500 2.038400e-02 5.232543e-08 FALSE TRUE
MSTRG.462.24 ENSG00000133226 No_inf pgKDN_inf SRRM1 protein_coding   42.85702 42.25822 41.10087 0.5666753 2.742372 -0.04005368 2.402484 5.506205 0.000000 0.9666091 0.0000000 -9.1075324 0.05563333 0.129625 0.000000 -0.129625 5.232543e-08 5.232543e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133226 E001 0.0000000       1 24631716 24631777 62 +      
ENSG00000133226 E002 0.0000000       1 24633019 24633065 47 +      
ENSG00000133226 E003 0.0000000       1 24633066 24633099 34 +      
ENSG00000133226 E004 0.0000000       1 24635644 24635877 234 +      
ENSG00000133226 E005 0.0000000       1 24641231 24641392 162 +      
ENSG00000133226 E006 0.5071304 0.0157115155 0.0494402823 0.219249481 1 24643200 24643271 72 + 0.000 0.293 12.211
ENSG00000133226 E007 0.5071304 0.0157115155 0.0494402823 0.219249481 1 24643272 24643272 1 + 0.000 0.293 14.577
ENSG00000133226 E008 0.5071304 0.0157115155 0.0494402823 0.219249481 1 24643273 24643274 2 + 0.000 0.293 14.577
ENSG00000133226 E009 1.2328146 0.0105948427 0.5708022338 0.807111336 1 24643275 24643287 13 + 0.300 0.388 0.536
ENSG00000133226 E010 2.2089048 0.1328692699 0.7919541646 0.920504632 1 24643288 24643292 5 + 0.476 0.532 0.273
ENSG00000133226 E011 3.1531385 0.0068709085 0.2086794882 0.492729162 1 24643293 24643298 6 + 0.698 0.532 -0.727
ENSG00000133226 E012 3.7597723 0.0128821410 0.1880424296 0.466287382 1 24643299 24643301 3 + 0.758 0.590 -0.712
ENSG00000133226 E013 3.7522507 0.0040775408 0.0866695043 0.305099735 1 24643302 24643304 3 + 0.777 0.562 -0.912
ENSG00000133226 E014 3.7522507 0.0040775408 0.0866695043 0.305099735 1 24643305 24643307 3 + 0.777 0.562 -0.912
ENSG00000133226 E015 13.6791912 0.0010203730 0.3406324181 0.632233005 1 24643308 24643347 40 + 1.202 1.131 -0.256
ENSG00000133226 E016 0.3724111 0.1787696588 0.6481715371   1 24643559 24643732 174 + 0.097 0.171 0.950
ENSG00000133226 E017 22.3620902 0.0153706675 0.4657965607 0.734746616 1 24645984 24646073 90 + 1.396 1.341 -0.191
ENSG00000133226 E018 23.1922405 0.0162794041 0.2799425824 0.573221633 1 24646667 24646789 123 + 1.426 1.341 -0.292
ENSG00000133226 E019 2.8946478 0.0084934726 0.0003276064 0.006247923 1 24646790 24647078 289 + 0.242 0.764 2.688
ENSG00000133226 E020 4.7173853 0.0032002932 0.0310078711 0.165828311 1 24647079 24647208 130 + 0.601 0.861 1.066
ENSG00000133226 E021 10.5232050 0.1043335872 0.1313531178 0.384520140 1 24647209 24647813 605 + 0.928 1.153 0.823
ENSG00000133226 E022 5.4530763 0.0026830938 0.0475817075 0.214441070 1 24647814 24648023 210 + 0.675 0.902 0.902
ENSG00000133226 E023 5.4716194 0.0040887730 0.0098745116 0.079609975 1 24648024 24648166 143 + 0.627 0.927 1.205
ENSG00000133226 E024 12.0256834 0.0017904588 0.0016181105 0.021676893 1 24648167 24648533 367 + 0.953 1.221 0.973
ENSG00000133226 E025 2.8752348 0.0049461992 0.0075116858 0.066243680 1 24648534 24648617 84 + 0.351 0.727 1.799
ENSG00000133226 E026 5.7487400 0.0023927430 0.0001528721 0.003351628 1 24648618 24648858 241 + 0.543 0.985 1.799
ENSG00000133226 E027 34.0097702 0.0004192989 0.3547485629 0.644447741 1 24648859 24649029 171 + 1.566 1.522 -0.153
ENSG00000133226 E028 13.3232307 0.0011696400 0.5021322734 0.761945605 1 24649971 24649987 17 + 1.182 1.131 -0.182
ENSG00000133226 E029 28.5483470 0.0112897832 0.2184351731 0.505042568 1 24649988 24650086 99 + 1.513 1.427 -0.296
ENSG00000133226 E030 0.3716209 0.0166258285 0.6074842489   1 24650565 24650627 63 + 0.097 0.171 0.951
ENSG00000133226 E031 22.9622091 0.0006128661 0.2550257453 0.546966181 1 24651409 24651498 90 + 1.413 1.346 -0.234
ENSG00000133226 E032 11.2997948 0.0015710850 0.6619420961 0.858986214 1 24651499 24651519 21 + 1.068 1.107 0.139
ENSG00000133226 E033 21.7812805 0.0006968008 0.5795399091 0.812268534 1 24651520 24651612 93 + 1.374 1.341 -0.114
ENSG00000133226 E034 19.5856366 0.0242027688 0.8024045250 0.926385692 1 24652434 24652496 63 + 1.320 1.306 -0.049
ENSG00000133226 E035 21.5511400 0.0007625923 0.7973959499 0.923486218 1 24652497 24652628 132 + 1.360 1.346 -0.049
ENSG00000133226 E036 9.7878442 0.0112140084 0.5712795232 0.807489839 1 24652913 24652927 15 + 1.059 1.006 -0.194
ENSG00000133226 E037 20.9501728 0.0024491002 0.8618370323 0.952176336 1 24652928 24653032 105 + 1.346 1.336 -0.032
ENSG00000133226 E038 0.3816610 0.0298497234 0.1126852945   1 24654306 24654343 38 + 0.000 0.236 14.119
ENSG00000133226 E039 29.3034848 0.0009489770 0.1143890922 0.356347599 1 24654855 24655010 156 + 1.523 1.439 -0.290
ENSG00000133226 E040 13.1977203 0.0070258866 0.4680956265 0.736424285 1 24655011 24655021 11 + 1.182 1.123 -0.210
ENSG00000133226 E041 14.9064590 0.0013018176 0.3536856387 0.643357727 1 24655022 24655053 32 + 1.235 1.168 -0.239
ENSG00000133226 E042 18.9312598 0.0007364184 0.2003136108 0.482348077 1 24655054 24655123 70 + 1.341 1.257 -0.292
ENSG00000133226 E043 7.2081506 0.0023025951 0.4296194076 0.707801762 1 24655124 24655129 6 + 0.953 0.875 -0.294
ENSG00000133226 E044 18.6022322 0.0007650454 0.5747722256 0.809584340 1 24660719 24660799 81 + 1.310 1.274 -0.125
ENSG00000133226 E045 0.1176306 0.0116714953 0.5178639723   1 24660800 24660975 176 + 0.097 0.000 -13.466
ENSG00000133226 E046 7.4947462 0.0018624181 0.6272986043 0.839945450 1 24661310 24661312 3 + 0.902 0.951 0.188
ENSG00000133226 E047 19.1488813 0.0008587429 0.5773791375 0.811141272 1 24661313 24661396 84 + 1.283 1.322 0.136
ENSG00000133226 E048 0.4907673 0.0953415616 0.9746031014   1 24661397 24661405 9 + 0.176 0.171 -0.050
ENSG00000133226 E049 25.4877319 0.0108147134 0.9993747651 1.000000000 1 24662660 24662804 145 + 1.421 1.423 0.006
ENSG00000133226 E050 2.5113529 0.0060843387 0.0015366663 0.020844708 1 24662805 24663068 264 + 0.242 0.707 2.453
ENSG00000133226 E051 7.1816666 0.0019558223 0.0266082174 0.151228129 1 24663183 24663224 42 + 0.777 1.006 0.877
ENSG00000133226 E052 2.3655579 0.0070761735 0.0460080291 0.210270066 1 24666555 24666814 260 + 0.351 0.640 1.436
ENSG00000133226 E053 24.0129877 0.0005798437 0.0696844566 0.266948042 1 24666815 24666925 111 + 1.336 1.446 0.383
ENSG00000133226 E054 64.7602141 0.0040450844 0.7584185226 0.905148029 1 24669123 24669582 460 + 1.824 1.811 -0.044
ENSG00000133226 E055 11.0913661 0.0048988103 0.2034989832 0.486099901 1 24669583 24669587 5 + 1.137 1.026 -0.400
ENSG00000133226 E056 2.7366463 0.0067460595 0.0405619795 0.195362547 1 24669588 24670119 532 + 0.397 0.686 1.366
ENSG00000133226 E057 36.9315501 0.0004523341 0.5922554626 0.819926745 1 24670120 24670315 196 + 1.564 1.591 0.095
ENSG00000133226 E058 39.5679327 0.0003964250 0.9463281292 0.985664316 1 24671386 24671595 210 + 1.608 1.607 -0.005
ENSG00000133226 E059 170.0470333 0.0001784758 0.6682759338 0.861937876 1 24672182 24673281 1100 + 2.236 2.229 -0.024

Help

Please Click HERE to learn more details about the results from DEXseq.