ENSG00000133315

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000255681 ENSG00000133315 No_inf pgKDN_inf MACROD1 protein_coding protein_coding 6.893895 10.48862 2.495527 2.383827 0.7168412 -2.067014 0.8808529 1.78343121 0.6494290 0.08041924 0.2751592 -1.443433 0.21099167 0.200250 0.368225 0.167975 0.8478779695 0.0002986192 FALSE TRUE
ENST00000538595 ENSG00000133315 No_inf pgKDN_inf MACROD1 protein_coding protein_coding_CDS_not_defined 6.893895 10.48862 2.495527 2.383827 0.7168412 -2.067014 0.6900203 0.07944737 1.0087142 0.07944737 0.2548554 3.509567 0.30639167 0.005425 0.446700 0.441275 0.0002986192 0.0002986192 FALSE TRUE
ENST00000542105 ENSG00000133315 No_inf pgKDN_inf MACROD1 protein_coding retained_intron 6.893895 10.48862 2.495527 2.383827 0.7168412 -2.067014 1.0900205 2.23999373 0.5138491 0.53747391 0.5138491 -2.102698 0.16722500 0.226050 0.113575 -0.112475 0.6960469874 0.0002986192   FALSE
ENST00000543422 ENSG00000133315 No_inf pgKDN_inf MACROD1 protein_coding protein_coding_CDS_not_defined 6.893895 10.48862 2.495527 2.383827 0.7168412 -2.067014 0.1078449 0.00000000 0.3235346 0.00000000 0.3235346 5.059765 0.02383333 0.000000 0.071500 0.071500 0.5070773483 0.0002986192   FALSE
ENST00000545464 ENSG00000133315 No_inf pgKDN_inf MACROD1 protein_coding retained_intron 6.893895 10.48862 2.495527 2.383827 0.7168412 -2.067014 0.3194736 0.71525129 0.0000000 0.52743648 0.0000000 -6.180409 0.04226667 0.116950 0.000000 -0.116950 0.8679747381 0.0002986192 FALSE TRUE
MSTRG.4884.8 ENSG00000133315 No_inf pgKDN_inf MACROD1 protein_coding   6.893895 10.48862 2.495527 2.383827 0.7168412 -2.067014 3.7591464 5.67049666 0.0000000 2.33374816 0.0000000 -9.149873 0.22621667 0.451300 0.000000 -0.451300 0.0694142180 0.0002986192   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133315 E001 0.3801504 0.019361674 0.476731634   11 63998558 63998559 2 - 0.000 0.174 10.992
ENSG00000133315 E002 0.3801504 0.019361674 0.476731634   11 63998560 63998565 6 - 0.000 0.174 10.993
ENSG00000133315 E003 0.3801504 0.019361674 0.476731634   11 63998566 63998569 4 - 0.000 0.174 10.993
ENSG00000133315 E004 2.2296962 0.020233126 0.584925153 0.8155353 11 63998570 63998687 118 - 0.504 0.473 -0.155
ENSG00000133315 E005 0.8610974 0.012731298 0.385127017 0.6712126 11 63998838 63998872 35 - 0.321 0.219 -0.740
ENSG00000133315 E006 1.1243725 0.011265441 0.704251855 0.8798091 11 63998955 63999000 46 - 0.238 0.332 0.653
ENSG00000133315 E007 0.6250460 0.016282708 0.738944423 0.8964798 11 63999001 63999036 36 - 0.135 0.219 0.845
ENSG00000133315 E008 1.8947738 0.008237887 0.035882615 0.1817006 11 63999037 63999330 294 - 0.135 0.518 2.653
ENSG00000133315 E009 1.1222649 0.011712328 0.701494449 0.8784034 11 63999331 63999382 52 - 0.238 0.332 0.653
ENSG00000133315 E010 0.4884066 0.018673502 0.342243720   11 63999383 63999404 22 - 0.238 0.123 -1.155
ENSG00000133315 E011 0.8601536 0.014646155 0.388981739 0.6748807 11 63999530 63999560 31 - 0.321 0.219 -0.740
ENSG00000133315 E012 2.1032564 0.007014898 0.477683618 0.7439006 11 63999642 63999763 122 - 0.504 0.448 -0.280
ENSG00000133315 E013 1.0159309 0.158519955 0.089666490 0.3111291 11 64000074 64000226 153 - 0.000 0.364 12.408
ENSG00000133315 E014 2.2604811 0.011214353 0.262592424 0.5554352 11 64000227 64000343 117 - 0.321 0.539 1.167
ENSG00000133315 E015 0.0000000       11 64009013 64009143 131 -      
ENSG00000133315 E016 0.4993265 0.016799602 1.000000000   11 64015252 64015281 30 - 0.135 0.174 0.430
ENSG00000133315 E017 1.2691626 0.010256948 0.024281772 0.1428461 11 64115914 64115986 73 - 0.000 0.422 12.730
ENSG00000133315 E018 0.0000000       11 64126854 64126934 81 -      
ENSG00000133315 E019 0.8358242 0.014892822 0.001195213 0.0171533 11 64148747 64149034 288 - 0.504 0.066 -3.740
ENSG00000133315 E020 3.4465303 0.004876916 0.065444378 0.2576595 11 64151239 64151355 117 - 0.731 0.559 -0.740
ENSG00000133315 E021 1.8570122 0.010981672 0.626462808 0.8394820 11 64152292 64152393 102 - 0.451 0.422 -0.155
ENSG00000133315 E022 1.9961046 0.014075710 0.812215729 0.9309356 11 64165697 64166113 417 - 0.391 0.473 0.430

Help

Please Click HERE to learn more details about the results from DEXseq.