ENSG00000133422

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397641 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding protein_coding 48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 2.712732 1.371853 3.178325 0.3323142 0.7025261 1.2061949 0.06140833 0.028650 0.075950 0.047300 0.494660664 0.006085282 FALSE TRUE
ENST00000476152 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding retained_intron 48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 5.117450 6.800311 4.433820 0.8468214 0.6295548 -0.6159205 0.11113333 0.142350 0.099525 -0.042825 0.834248141 0.006085282 FALSE FALSE
ENST00000675317 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding retained_intron 48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 3.767030 4.067354 4.532493 1.3607733 1.5234757 0.1558512 0.07754167 0.082300 0.099475 0.017175 0.988131538 0.006085282 FALSE TRUE
ENST00000675601 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding protein_coding_CDS_not_defined 48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 3.267713 2.462954 3.665541 1.4243227 2.1286767 0.5717210 0.07405000 0.057750 0.095375 0.037625 0.995701172 0.006085282 FALSE TRUE
ENST00000675798 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding retained_intron 48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 5.831593 4.435689 9.350059 2.7085990 3.7250174 1.0741105 0.11494167 0.076300 0.189825 0.113525 0.707288879 0.006085282 FALSE TRUE
ENST00000676263 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding retained_intron 48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 4.703094 2.822183 2.193032 1.6836467 2.1930320 -0.3624239 0.11001667 0.060575 0.057450 -0.003125 0.829478471 0.006085282 FALSE TRUE
MSTRG.19270.2 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding   48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 7.665800 4.324807 9.691484 0.7272295 1.1905116 1.1622377 0.16675833 0.081850 0.216825 0.134975 0.038764967 0.006085282 FALSE TRUE
MSTRG.19270.20 ENSG00000133422 No_inf pgKDN_inf MORC2 protein_coding   48.19555 52.27391 46.22989 7.277159 7.463207 -0.177229 9.607472 19.856798 3.195411 6.6158181 3.1954111 -2.6317780 0.16999167 0.353250 0.046575 -0.306675 0.006085282 0.006085282   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133422 E001 0.0000000       22 30925130 30926595 1466 -      
ENSG00000133422 E002 0.0000000       22 30926596 30926610 15 -      
ENSG00000133422 E003 0.0000000       22 30926611 30926636 26 -      
ENSG00000133422 E004 7.2080173 0.0020845503 5.660722e-01 0.8045555646 22 30926637 30926712 76 - 0.886 0.943 0.219
ENSG00000133422 E005 8.2971672 0.0017818070 7.568952e-01 0.9042999870 22 30926713 30926732 20 - 0.953 0.983 0.110
ENSG00000133422 E006 21.8795944 0.0006606961 2.433607e-01 0.5333486502 22 30926733 30926871 139 - 1.389 1.317 -0.253
ENSG00000133422 E007 0.2441377 0.0163299765 8.440429e-01   22 30926872 30927529 658 - 0.085 0.106 0.366
ENSG00000133422 E008 0.7449400 0.0718623894 2.913421e-01 0.5848965235 22 30927530 30927803 274 - 0.156 0.325 1.366
ENSG00000133422 E009 0.4904501 0.0161392443 8.021543e-01   22 30927804 30928018 215 - 0.156 0.192 0.366
ENSG00000133422 E010 9.1020750 0.0017574836 2.652442e-01 0.5583577263 22 30928019 30928027 9 - 1.047 0.943 -0.382
ENSG00000133422 E011 22.3632251 0.0006212441 2.646553e-01 0.5577845080 22 30928028 30928207 180 - 1.397 1.328 -0.239
ENSG00000133422 E012 0.1187032 0.0118621074 6.908509e-01   22 30928208 30928228 21 - 0.085 0.000 -9.469
ENSG00000133422 E013 1.2224564 0.0105036419 6.926060e-01 0.8741897471 22 30932359 30932452 94 - 0.318 0.378 0.366
ENSG00000133422 E014 44.7154288 0.0003869489 6.276147e-03 0.0583214503 22 30932545 30932769 225 - 1.600 1.719 0.405
ENSG00000133422 E015 0.1170040 0.0116446485 6.910578e-01   22 30932770 30932888 119 - 0.085 0.000 -9.470
ENSG00000133422 E016 34.7266795 0.0005667878 7.529391e-01 0.9027349457 22 30932889 30933030 142 - 1.558 1.543 -0.052
ENSG00000133422 E017 0.0000000       22 30933031 30933095 65 -      
ENSG00000133422 E018 19.7538658 0.0097196622 7.503169e-01 0.9015034680 22 30933466 30933520 55 - 1.305 1.328 0.080
ENSG00000133422 E019 0.0000000       22 30933521 30933597 77 -      
ENSG00000133422 E020 0.0000000       22 30933694 30933777 84 -      
ENSG00000133422 E021 23.3439383 0.0016314315 2.216368e-01 0.5088621960 22 30934060 30934191 132 - 1.349 1.424 0.260
ENSG00000133422 E022 48.6596907 0.0003035851 7.096363e-01 0.8825088459 22 30934781 30935161 381 - 1.687 1.703 0.054
ENSG00000133422 E023 0.0000000       22 30935162 30935218 57 -      
ENSG00000133422 E024 16.2331996 0.0013079670 7.479961e-01 0.9005751771 22 30935248 30935322 75 - 1.224 1.247 0.083
ENSG00000133422 E025 15.8192831 0.0009422284 4.968810e-01 0.7577399602 22 30936511 30936577 67 - 1.246 1.197 -0.173
ENSG00000133422 E026 13.9065994 0.0010052654 1.963425e-02 0.1255523669 22 30936578 30936643 66 - 1.246 1.063 -0.653
ENSG00000133422 E027 0.0000000       22 30936644 30936668 25 -      
ENSG00000133422 E028 13.3781557 0.0009778898 5.531384e-01 0.7963528088 22 30936932 30937002 71 - 1.177 1.130 -0.165
ENSG00000133422 E029 10.3954249 0.0012895425 4.044400e-01 0.6871555685 22 30937003 30937037 35 - 1.021 1.093 0.264
ENSG00000133422 E030 20.8457765 0.0008850692 8.460488e-01 0.9453437014 22 30937583 30937711 129 - 1.332 1.345 0.044
ENSG00000133422 E031 16.2621864 0.0020012588 2.382325e-01 0.5270967970 22 30937815 30937969 155 - 1.195 1.280 0.301
ENSG00000133422 E032 15.4195841 0.0011590621 1.576551e-01 0.4242786555 22 30938065 30938205 141 - 1.164 1.267 0.366
ENSG00000133422 E033 4.2306172 0.0202760900 1.055979e-03 0.0156121692 22 30938206 30939620 1415 - 0.468 0.900 1.840
ENSG00000133422 E034 14.9357213 0.0010013213 2.936023e-01 0.5871797764 22 30939621 30939706 86 - 1.235 1.156 -0.278
ENSG00000133422 E035 0.3727544 0.0168036053 4.390540e-01   22 30939707 30939958 252 - 0.085 0.192 1.366
ENSG00000133422 E036 10.0679833 0.0040665572 2.535199e-01 0.5450803496 22 30939959 30940041 83 - 1.087 0.983 -0.381
ENSG00000133422 E037 0.3729107 0.1495841462 4.776463e-01   22 30940042 30940724 683 - 0.085 0.192 1.366
ENSG00000133422 E038 9.7993091 0.0015242170 5.796323e-02 0.2409579879 22 30940758 30940837 80 - 1.102 0.930 -0.634
ENSG00000133422 E039 15.5663581 0.0009408850 4.803623e-01 0.7458074161 22 30941433 30941558 126 - 1.240 1.189 -0.182
ENSG00000133422 E040 6.2127739 0.0025213815 9.347201e-01 0.9812023019 22 30941891 30941899 9 - 0.861 0.852 -0.033
ENSG00000133422 E041 16.6474764 0.0011060424 3.103639e-01 0.6035036126 22 30941900 30942002 103 - 1.276 1.204 -0.254
ENSG00000133422 E042 24.3559392 0.0331698684 7.314424e-01 0.8932539387 22 30942112 30942271 160 - 1.419 1.381 -0.130
ENSG00000133422 E043 19.3257735 0.0008713985 2.043989e-01 0.4872729199 22 30946341 30946449 109 - 1.266 1.350 0.293
ENSG00000133422 E044 0.3720642 0.0168025447 4.389051e-01   22 30947014 30947172 159 - 0.085 0.192 1.366
ENSG00000133422 E045 20.1678516 0.0048164039 3.134590e-01 0.6065839143 22 30949752 30949842 91 - 1.291 1.361 0.243
ENSG00000133422 E046 13.1353599 0.0016881010 5.371213e-01 0.7861570726 22 30950377 30950445 69 - 1.170 1.121 -0.175
ENSG00000133422 E047 6.8524473 0.0022613504 5.037377e-01 0.7632055573 22 30956763 30956797 35 - 0.861 0.930 0.263
ENSG00000133422 E048 10.7327579 0.0015383201 9.099507e-01 0.9714618625 22 30958641 30958694 54 - 1.063 1.073 0.036
ENSG00000133422 E049 7.3100890 0.0020114201 5.997378e-04 0.0100570063 22 30958695 30959001 307 - 0.725 1.073 1.329
ENSG00000133422 E050 0.8803880 0.0123313691 2.263124e-02 0.1369606350 22 30960252 30960265 14 - 0.085 0.426 2.951
ENSG00000133422 E051 2.1131091 0.0071848178 2.724368e-02 0.1534740339 22 30963225 30963334 110 - 0.318 0.637 1.629
ENSG00000133422 E052 0.9879541 0.0130918975 2.917204e-01 0.5851242356 22 30963335 30963447 113 - 0.217 0.378 1.103
ENSG00000133422 E053 5.1587088 0.0102193578 1.711494e-01 0.4434652093 22 30967066 30967821 756 - 0.707 0.869 0.641
ENSG00000133422 E054 56.8930835 0.0002688015 1.495078e-05 0.0004836634 22 30967822 30969053 1232 - 1.830 1.660 -0.575

Help

Please Click HERE to learn more details about the results from DEXseq.