ENSG00000133612

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000461065 ENSG00000133612 No_inf pgKDN_inf AGAP3 protein_coding protein_coding 112.2038 55.63896 123.5788 1.165333 2.24068 1.151121 15.931511 10.049860 20.647871 2.6173852 1.9869643 1.0380813 0.15128333 0.178875 0.167375 -0.011500 1.00000000 0.0107702 FALSE  
ENST00000467250 ENSG00000133612 No_inf pgKDN_inf AGAP3 protein_coding protein_coding_CDS_not_defined 112.2038 55.63896 123.5788 1.165333 2.24068 1.151121 7.154610 4.419737 5.549418 1.1793052 1.0250287 0.3277127 0.06650000 0.080475 0.045350 -0.035125 0.73920048 0.0107702    
ENST00000473312 ENSG00000133612 No_inf pgKDN_inf AGAP3 protein_coding protein_coding 112.2038 55.63896 123.5788 1.165333 2.24068 1.151121 12.375906 2.907034 15.684949 0.3020139 0.6202208 2.4277265 0.09906667 0.052175 0.127200 0.075025 0.04259359 0.0107702 FALSE  
ENST00000478320 ENSG00000133612 No_inf pgKDN_inf AGAP3 protein_coding protein_coding_CDS_not_defined 112.2038 55.63896 123.5788 1.165333 2.24068 1.151121 6.064818 5.354691 4.194625 0.1848059 1.3577077 -0.3515181 0.06171667 0.096325 0.033775 -0.062550 0.11918540 0.0107702    
ENST00000483971 ENSG00000133612 No_inf pgKDN_inf AGAP3 protein_coding protein_coding_CDS_not_defined 112.2038 55.63896 123.5788 1.165333 2.24068 1.151121 7.079487 1.061146 7.890154 1.0611459 3.5921889 2.8827259 0.05298333 0.019650 0.063225 0.043575 0.44205612 0.0107702    
ENST00000622464 ENSG00000133612 No_inf pgKDN_inf AGAP3 protein_coding protein_coding 112.2038 55.63896 123.5788 1.165333 2.24068 1.151121 33.603173 15.858446 39.217962 2.4354133 0.5734292 1.3057216 0.29852500 0.286575 0.317875 0.031300 0.84851647 0.0107702 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133612 E001 0.1187032 0.0118162089 1.000000e+00   7 151085831 151085866 36 + 0.067 0.000 -10.285
ENSG00000133612 E002 0.7256219 0.0363334022 9.506274e-01 9.874076e-01 7 151085867 151086009 143 + 0.223 0.234 0.084
ENSG00000133612 E003 0.6161394 0.0147316206 2.049190e-01 4.880809e-01 7 151086010 151086060 51 + 0.126 0.316 1.669
ENSG00000133612 E004 0.3533378 0.0157430242 3.496881e-01   7 151086402 151086414 13 + 0.177 0.000 -14.358
ENSG00000133612 E005 1.6706409 0.0081049953 1.283973e-01 3.799088e-01 7 151086415 151086474 60 + 0.480 0.234 -1.501
ENSG00000133612 E006 8.2617545 0.0048057054 3.302554e-02 1.725801e-01 7 151086475 151086741 267 + 1.010 0.777 -0.890
ENSG00000133612 E007 3.6133811 0.2272867260 9.147200e-01 9.731056e-01 7 151086742 151086786 45 + 0.656 0.624 -0.136
ENSG00000133612 E008 2.0584210 0.3390887374 6.949870e-01 8.753851e-01 7 151086787 151086791 5 + 0.455 0.497 0.210
ENSG00000133612 E009 14.9413657 0.0165953043 4.287408e-01 7.071686e-01 7 151086792 151086894 103 + 1.203 1.129 -0.262
ENSG00000133612 E010 41.6161718 0.0006325552 6.866595e-03 6.227740e-02 7 151086895 151087066 172 + 1.647 1.510 -0.468
ENSG00000133612 E011 14.2490465 0.0053285629 3.051331e-03 3.492747e-02 7 151087067 151087072 6 + 1.234 0.964 -0.977
ENSG00000133612 E012 0.2543986 0.0159980081 7.414790e-02   7 151087073 151087204 132 + 0.000 0.234 14.316
ENSG00000133612 E013 0.3723465 0.0165247278 2.249172e-01   7 151089712 151090165 454 + 0.067 0.234 2.084
ENSG00000133612 E014 0.1186381 0.0117974536 1.000000e+00   7 151090493 151090547 55 + 0.067 0.000 -12.873
ENSG00000133612 E015 0.0000000       7 151112184 151112244 61 +      
ENSG00000133612 E016 0.1268540 0.0122921093 2.385372e-01   7 151114678 151115641 964 + 0.000 0.132 13.381
ENSG00000133612 E017 0.2340080 0.2263071191 6.911485e-01   7 151116307 151116650 344 + 0.126 0.000 -12.974
ENSG00000133612 E018 28.3262216 0.0005116208 1.049425e-03 1.554937e-02 7 151116793 151116851 59 + 1.502 1.299 -0.704
ENSG00000133612 E019 36.6824650 0.0005778881 8.896295e-03 7.435500e-02 7 151117095 151117182 88 + 1.595 1.454 -0.482
ENSG00000133612 E020 19.8396522 0.0188201365 8.737265e-02 3.063878e-01 7 151117371 151117391 21 + 1.343 1.183 -0.560
ENSG00000133612 E021 29.6827040 0.0011356004 3.421671e-01 6.335854e-01 7 151117392 151117456 65 + 1.481 1.426 -0.189
ENSG00000133612 E022 48.4920659 0.0003000522 2.730976e-01 5.668802e-01 7 151117636 151117749 114 + 1.686 1.638 -0.166
ENSG00000133612 E023 22.3499614 0.0006127732 9.470776e-01 9.859230e-01 7 151117750 151117753 4 + 1.346 1.343 -0.010
ENSG00000133612 E024 26.2248472 0.0014398749 8.523405e-01 9.478202e-01 7 151117754 151117777 24 + 1.407 1.420 0.044
ENSG00000133612 E025 3.0107614 0.0050236777 6.587796e-01 8.574650e-01 7 151117778 151118162 385 + 0.605 0.543 -0.278
ENSG00000133612 E026 0.6263978 0.0141384890 2.949387e-02 1.613722e-01 7 151118209 151118209 1 + 0.067 0.385 3.084
ENSG00000133612 E027 37.6526017 0.0009058280 2.791297e-01 5.723958e-01 7 151118210 151118267 58 + 1.543 1.600 0.194
ENSG00000133612 E028 24.5892525 0.0006072685 3.132747e-01 6.064074e-01 7 151118268 151118293 26 + 1.362 1.426 0.221
ENSG00000133612 E029 31.5630614 0.0097638557 9.097355e-01 9.713623e-01 7 151118294 151118344 51 + 1.486 1.495 0.034
ENSG00000133612 E030 0.9791974 0.0245163948 3.075438e-01 6.007432e-01 7 151118345 151118473 129 + 0.223 0.385 1.084
ENSG00000133612 E031 1.0721580 0.0110693481 1.459054e-01 4.067854e-01 7 151118474 151118504 31 + 0.370 0.132 -1.916
ENSG00000133612 E032 42.8844484 0.0113352772 6.725498e-01 8.644460e-01 7 151118505 151118632 128 + 1.627 1.600 -0.091
ENSG00000133612 E033 0.0000000       7 151119197 151119254 58 +      
ENSG00000133612 E034 19.1996831 0.0007112878 7.249928e-01 8.895660e-01 7 151119987 151120015 29 + 1.290 1.266 -0.082
ENSG00000133612 E035 28.0475582 0.0005177593 9.467120e-01 9.857898e-01 7 151120016 151120070 55 + 1.438 1.443 0.018
ENSG00000133612 E036 33.9994912 0.0006303410 3.327742e-01 6.249157e-01 7 151120071 151120145 75 + 1.537 1.485 -0.177
ENSG00000133612 E037 1.1769523 0.0106432823 1.297885e-02 9.526421e-02 7 151120520 151120567 48 + 0.428 0.000 -15.972
ENSG00000133612 E038 2.6713678 0.1880218553 6.604965e-01 8.583058e-01 7 151120568 151120745 178 + 0.503 0.624 0.554
ENSG00000133612 E039 0.5072867 0.0518868354 7.134974e-03 6.384896e-02 7 151120746 151121033 288 + 0.000 0.385 15.004
ENSG00000133612 E040 50.8409271 0.0002848978 3.016942e-15 5.232017e-13 7 151122725 151123621 897 + 1.789 1.390 -1.363
ENSG00000133612 E041 1.6725845 0.0571077882 1.555528e-01 4.214813e-01 7 151123622 151123793 172 + 0.480 0.234 -1.501
ENSG00000133612 E042 29.4531194 0.0004546722 6.424896e-01 8.483581e-01 7 151123794 151123886 93 + 1.468 1.443 -0.088
ENSG00000133612 E043 0.4981926 0.4939158028 2.563447e-01   7 151128333 151128576 244 + 0.067 0.316 2.669
ENSG00000133612 E044 0.1176306 0.0117314055 1.000000e+00   7 151128577 151128579 3 + 0.067 0.000 -12.874
ENSG00000133612 E045 17.7885828 0.0185743797 8.794059e-02 3.076067e-01 7 151128580 151128595 16 + 1.297 1.141 -0.553
ENSG00000133612 E046 35.4789844 0.0087531128 6.522784e-02 2.571260e-01 7 151128596 151128684 89 + 1.576 1.454 -0.417
ENSG00000133612 E047 1.5849863 0.1954434769 3.754923e-01 6.630170e-01 7 151130204 151130271 68 + 0.338 0.497 0.863
ENSG00000133612 E048 2.1476204 0.0070380111 1.411033e-01 3.996989e-01 7 151131072 151131286 215 + 0.547 0.316 -1.238
ENSG00000133612 E049 21.7355841 0.0006174192 7.717431e-01 9.121492e-01 7 151134400 151134424 25 + 1.339 1.321 -0.063
ENSG00000133612 E050 31.0128952 0.0022231510 3.233539e-01 6.159851e-01 7 151134425 151134481 57 + 1.461 1.520 0.201
ENSG00000133612 E051 34.2321710 0.0006133146 3.598966e-04 6.749188e-03 7 151134482 151134568 87 + 1.451 1.638 0.639
ENSG00000133612 E052 6.2441807 0.0110829345 1.872156e-02 1.214274e-01 7 151136226 151136560 335 + 0.730 0.996 1.028
ENSG00000133612 E053 10.1202614 0.0051880973 9.206251e-07 4.332722e-05 7 151137730 151138142 413 + 0.816 1.266 1.655
ENSG00000133612 E054 40.2959543 0.0003665196 5.554467e-01 7.980145e-01 7 151138143 151138313 171 + 1.581 1.612 0.104
ENSG00000133612 E055 4.8094697 0.0102212983 9.908448e-04 1.489831e-02 7 151139568 151139978 411 + 0.567 0.964 1.608
ENSG00000133612 E056 37.4616930 0.0038047978 8.625979e-01 9.525857e-01 7 151139979 151140116 138 + 1.564 1.555 -0.029
ENSG00000133612 E057 2.8615478 0.0873964604 2.618673e-03 3.115032e-02 7 151140117 151140283 167 + 0.338 0.826 2.276
ENSG00000133612 E058 10.1905695 0.0029397770 5.171305e-05 1.369215e-03 7 151140284 151140876 593 + 0.868 1.231 1.328
ENSG00000133612 E059 12.4624064 0.0668936522 1.946810e-04 4.091944e-03 7 151140877 151141897 1021 + 0.888 1.357 1.693
ENSG00000133612 E060 59.7155770 0.0005912982 1.946437e-01 4.746108e-01 7 151141898 151142052 155 + 1.740 1.795 0.184
ENSG00000133612 E061 51.3649638 0.0007841205 2.298262e-01 5.183126e-01 7 151142163 151142253 91 + 1.676 1.730 0.185
ENSG00000133612 E062 71.7126910 0.0002792884 9.624835e-02 3.230882e-01 7 151142412 151142634 223 + 1.815 1.878 0.210
ENSG00000133612 E063 82.7338593 0.0026950204 6.523780e-01 8.535276e-01 7 151143341 151143596 256 + 1.892 1.911 0.065
ENSG00000133612 E064 204.5879664 0.0001321870 3.099128e-02 1.658053e-01 7 151143737 151144436 700 + 2.272 2.319 0.155

Help

Please Click HERE to learn more details about the results from DEXseq.