ENSG00000133687

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000539277 ENSG00000133687 No_inf pgKDN_inf TMTC1 protein_coding protein_coding 64.77908 27.56349 106.3891 0.6298214 2.990891 1.948132 18.019429 7.7185742 30.159653 1.8333690 3.1598072 1.9648239 0.27767500 0.28095 0.285400 0.004450 0.9835753747 0.0002809705 FALSE  
ENST00000551659 ENSG00000133687 No_inf pgKDN_inf TMTC1 protein_coding protein_coding 64.77908 27.56349 106.3891 0.6298214 2.990891 1.948132 4.340446 0.0000000 7.780235 0.0000000 2.2063660 9.6055230 0.05445000 0.00000 0.073375 0.073375 0.0002809705 0.0002809705 FALSE  
ENST00000552925 ENSG00000133687 No_inf pgKDN_inf TMTC1 protein_coding protein_coding_CDS_not_defined 64.77908 27.56349 106.3891 0.6298214 2.990891 1.948132 5.649103 0.4454766 10.914869 0.4454766 4.4633884 4.5840951 0.06765833 0.01525 0.099300 0.084050 0.4008193820 0.0002809705 FALSE  
MSTRG.6250.1 ENSG00000133687 No_inf pgKDN_inf TMTC1 protein_coding   64.77908 27.56349 106.3891 0.6298214 2.990891 1.948132 19.680778 6.4524895 31.531798 1.4384853 2.0999793 2.2871030 0.29331667 0.23370 0.296125 0.062425 0.7694003220 0.0002809705 FALSE  
MSTRG.6250.4 ENSG00000133687 No_inf pgKDN_inf TMTC1 protein_coding   64.77908 27.56349 106.3891 0.6298214 2.990891 1.948132 11.329946 9.3659588 18.004108 0.3434362 3.2277117 0.9420891 0.20727500 0.33990 0.169025 -0.170875 0.0548803882 0.0002809705 TRUE  
MSTRG.6250.5 ENSG00000133687 No_inf pgKDN_inf TMTC1 protein_coding   64.77908 27.56349 106.3891 0.6298214 2.990891 1.948132 4.004499 2.7635937 4.816446 0.5117239 0.4579944 0.7992048 0.07255000 0.10040 0.045450 -0.054950 0.4130889573 0.0002809705 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133687 E001 1.2047634 4.464033e-01 5.529858e-01 7.963031e-01 12 29500830 29500839 10 - 0.292 0.364 0.454
ENSG00000133687 E002 2.5279867 7.827188e-02 6.351667e-01 8.442071e-01 12 29500840 29500842 3 - 0.485 0.559 0.355
ENSG00000133687 E003 5.0990682 7.486277e-03 4.556878e-02 2.088643e-01 12 29500843 29500870 28 - 0.659 0.903 0.976
ENSG00000133687 E004 1358.5340703 3.165023e-05 6.193495e-21 1.786310e-18 12 29500871 29505598 4728 - 3.055 3.119 0.214
ENSG00000133687 E005 16.8061919 7.949321e-04 9.431865e-01 9.842133e-01 12 29505599 29505698 100 - 1.195 1.189 -0.021
ENSG00000133687 E006 45.3303666 8.913671e-04 4.674731e-01 7.358107e-01 12 29505699 29505976 278 - 1.615 1.577 -0.131
ENSG00000133687 E007 11.7166690 1.154195e-03 1.211983e-01 3.684937e-01 12 29505977 29505981 5 - 1.082 0.926 -0.576
ENSG00000133687 E008 396.4977064 9.303155e-05 2.162934e-03 2.706628e-02 12 29505982 29506986 1005 - 2.551 2.498 -0.176
ENSG00000133687 E009 45.9585150 1.252150e-03 2.511367e-01 5.423563e-01 12 29512043 29512120 78 - 1.596 1.655 0.200
ENSG00000133687 E010 62.1896087 2.432352e-04 6.463447e-01 8.503612e-01 12 29514482 29514604 123 - 1.745 1.725 -0.069
ENSG00000133687 E011 74.7828670 2.990742e-03 4.899273e-01 7.527542e-01 12 29516349 29516486 138 - 1.827 1.794 -0.111
ENSG00000133687 E012 67.4901399 2.188460e-04 1.282222e-01 3.795991e-01 12 29517427 29517571 145 - 1.791 1.725 -0.223
ENSG00000133687 E013 20.9257795 1.223011e-03 8.045352e-02 2.912788e-01 12 29518472 29518480 9 - 1.313 1.176 -0.484
ENSG00000133687 E014 48.4052726 2.871395e-04 8.826368e-04 1.364015e-02 12 29518481 29518607 127 - 1.672 1.494 -0.608
ENSG00000133687 E015 0.3805619 5.482541e-01 6.350482e-02   12 29519218 29519454 237 - 0.000 0.364 12.817
ENSG00000133687 E016 50.8013405 2.825801e-04 6.265446e-02 2.514851e-01 12 29520618 29520720 103 - 1.676 1.582 -0.320
ENSG00000133687 E017 3.2532335 1.110570e-02 8.050973e-01 9.278607e-01 12 29528346 29528482 137 - 0.573 0.609 0.161
ENSG00000133687 E018 9.0230125 1.568869e-02 4.697887e-04 8.323780e-03 12 29532568 29536208 3641 - 0.820 1.189 1.363
ENSG00000133687 E019 58.3451638 2.538173e-04 6.834975e-01 8.689903e-01 12 29536209 29536317 109 - 1.718 1.699 -0.063
ENSG00000133687 E020 76.2073758 2.760462e-04 5.223420e-02 2.269556e-01 12 29556857 29557000 144 - 1.846 1.766 -0.271
ENSG00000133687 E021 0.1268540 1.233810e-02 1.391938e-01   12 29568721 29568984 264 - 0.000 0.158 12.698
ENSG00000133687 E022 58.6360974 3.203574e-03 1.643728e-01 4.336374e-01 12 29572105 29572183 79 - 1.732 1.659 -0.248
ENSG00000133687 E023 37.5260825 5.300833e-03 2.595653e-01 5.520483e-01 12 29572184 29572218 35 - 1.544 1.469 -0.256
ENSG00000133687 E024 64.3530471 2.507493e-04 7.040626e-01 8.796837e-01 12 29583407 29583574 168 - 1.759 1.742 -0.056
ENSG00000133687 E025 44.5583575 3.179951e-04 8.639150e-01 9.529224e-01 12 29604178 29604299 122 - 1.601 1.592 -0.031
ENSG00000133687 E026 0.0000000       12 29609845 29609983 139 -      
ENSG00000133687 E027 58.4652338 9.022657e-03 1.804615e-01 4.559265e-01 12 29633147 29633336 190 - 1.733 1.651 -0.280
ENSG00000133687 E028 0.3635311 1.663834e-02 6.625920e-01   12 29640560 29641238 679 - 0.105 0.158 0.676
ENSG00000133687 E029 1.8586125 9.456285e-02 2.720341e-03 3.204074e-02 12 29650752 29650884 133 - 0.227 0.730 2.676
ENSG00000133687 E030 30.5447080 5.672819e-04 2.496355e-01 5.406079e-01 12 29659880 29659983 104 - 1.457 1.384 -0.254
ENSG00000133687 E031 22.9401503 6.000365e-04 2.588570e-02 1.487449e-01 12 29660804 29660885 82 - 1.357 1.189 -0.592
ENSG00000133687 E032 0.3726934 1.672450e-02 1.148369e-01   12 29661314 29661579 266 - 0.056 0.273 2.676
ENSG00000133687 E033 57.3350419 1.082410e-03 2.040047e-04 4.256398e-03 12 29751666 29751872 207 - 1.746 1.556 -0.646
ENSG00000133687 E034 63.7472285 2.829389e-03 1.205553e-01 3.673390e-01 12 29755709 29755885 177 - 1.769 1.691 -0.264
ENSG00000133687 E035 34.7336755 3.727976e-04 1.196609e-01 3.656249e-01 12 29758704 29758777 74 - 1.515 1.421 -0.324
ENSG00000133687 E036 38.5584499 4.466899e-03 1.226115e-01 3.705761e-01 12 29767898 29768075 178 - 1.560 1.462 -0.335
ENSG00000133687 E037 0.2447669 1.651856e-02 3.617020e-01   12 29782810 29783046 237 - 0.056 0.158 1.676
ENSG00000133687 E038 47.8886280 3.501906e-04 1.955888e-04 4.104624e-03 12 29783450 29783942 493 - 1.672 1.469 -0.694
ENSG00000133687 E039 0.3532727 1.577946e-02 6.155339e-01   12 29784308 29784759 452 - 0.149 0.000 -12.995

Help

Please Click HERE to learn more details about the results from DEXseq.