ENSG00000133805

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396553 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding protein_coding 153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 26.220671 1.632393 40.647867 0.9696636 7.509423 4.6296635 0.14365000 0.019125 0.219825 0.200700 0.003883575 0.003883575 FALSE TRUE
ENST00000529834 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding nonsense_mediated_decay 153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 9.469698 3.767022 12.876618 1.8224861 3.077215 1.7705527 0.05870833 0.045025 0.069125 0.024100 0.792589094 0.003883575 TRUE TRUE
ENST00000530864 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding protein_coding_CDS_not_defined 153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 29.270066 12.266999 38.436230 4.3019868 5.466169 1.6468842 0.18006667 0.138775 0.205850 0.067075 0.800190638 0.003883575 FALSE FALSE
MSTRG.4412.12 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding   153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 9.652023 7.603310 6.338374 1.3259842 0.848520 -0.2621368 0.06790000 0.090100 0.034350 -0.055750 0.119472013 0.003883575 TRUE TRUE
MSTRG.4412.19 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding   153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 22.265905 13.465948 26.278386 1.9791873 1.993414 0.9640388 0.14868333 0.161800 0.141625 -0.020175 0.913256057 0.003883575 FALSE TRUE
MSTRG.4412.22 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding   153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 9.203585 6.414860 9.212508 0.3460514 0.441321 0.5214941 0.06315000 0.076125 0.050150 -0.025975 0.562449282 0.003883575 FALSE TRUE
MSTRG.4412.25 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding   153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 9.921185 6.444241 11.548629 1.0703152 1.236904 0.8406510 0.06725000 0.077450 0.062150 -0.015300 0.865348109 0.003883575 FALSE TRUE
MSTRG.4412.27 ENSG00000133805 No_inf pgKDN_inf AMPD3 protein_coding   153.0608 84.73455 184.7945 3.665253 6.332746 1.124808 11.721525 10.698803 9.186303 0.8119999 0.457974 -0.2196713 0.08613333 0.128150 0.049675 -0.078475 0.017123043 0.003883575 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133805 E001 0.1265070 0.0122627132 2.738874e-01   11 10308313 10308673 361 + 0.000 0.126 10.768
ENSG00000133805 E002 0.0000000       11 10317671 10317768 98 +      
ENSG00000133805 E003 0.1265070 0.0122627132 2.738874e-01   11 10330570 10330659 90 + 0.000 0.126 12.933
ENSG00000133805 E004 0.0000000       11 10330660 10330709 50 +      
ENSG00000133805 E005 0.0000000       11 10357273 10357391 119 +      
ENSG00000133805 E006 0.0000000       11 10392282 10392405 124 +      
ENSG00000133805 E007 0.0000000       11 10408368 10408505 138 +      
ENSG00000133805 E008 0.1271363 0.0123361674 2.739087e-01   11 10410757 10410838 82 + 0.000 0.126 12.932
ENSG00000133805 E009 2.8497679 0.0050501244 3.325621e-03 3.732862e-02 11 10450321 10450496 176 + 0.385 0.782 1.826
ENSG00000133805 E010 1.5656967 0.0330801124 7.733222e-01 9.128354e-01 11 10450497 10450515 19 + 0.415 0.370 -0.251
ENSG00000133805 E011 3.4106143 0.0045271387 3.786491e-01 6.656064e-01 11 10450516 10450680 165 + 0.585 0.702 0.504
ENSG00000133805 E012 1.4714453 0.0093724436 2.834204e-01 5.771349e-01 11 10450681 10450699 19 + 0.316 0.480 0.919
ENSG00000133805 E013 1.0969917 0.0115439646 5.509748e-01 7.949779e-01 11 10450700 10450706 7 + 0.276 0.370 0.597
ENSG00000133805 E014 3.0560272 0.0047415803 1.774989e-01 4.521553e-01 11 10450707 10450764 58 + 0.520 0.702 0.804
ENSG00000133805 E015 5.3883128 0.0025808473 3.993208e-02 1.936952e-01 11 10450765 10450941 177 + 0.692 0.925 0.919
ENSG00000133805 E016 3.8742848 0.0083885674 9.688843e-01 9.936412e-01 11 10450942 10451043 102 + 0.676 0.672 -0.014
ENSG00000133805 E017 0.6184380 0.1539817587 2.879804e-01 5.815026e-01 11 10455264 10455281 18 + 0.132 0.303 1.504
ENSG00000133805 E018 4.0536425 0.2338740019 1.567887e-01 4.231718e-01 11 10455282 10455339 58 + 0.789 0.429 -1.616
ENSG00000133805 E019 7.1369830 0.1005780774 7.674666e-03 6.721222e-02 11 10455340 10455406 67 + 1.018 0.526 -2.001
ENSG00000133805 E020 7.6462025 0.0057003385 2.596190e-03 3.095574e-02 11 10455407 10455448 42 + 1.018 0.672 -1.349
ENSG00000133805 E021 15.8746766 0.0020254026 9.205327e-01 9.752146e-01 11 10456042 10456185 144 + 1.208 1.217 0.033
ENSG00000133805 E022 8.2287314 0.0016504879 8.807924e-01 9.599227e-01 11 10456186 10456210 25 + 0.955 0.942 -0.049
ENSG00000133805 E023 24.6017123 0.0016593853 7.164309e-01 8.857100e-01 11 10456211 10456402 192 + 1.383 1.408 0.087
ENSG00000133805 E024 7.0837376 0.0509264452 2.883117e-05 8.378128e-04 11 10457014 10457484 471 + 0.605 1.160 2.154
ENSG00000133805 E025 11.7173261 0.0044777419 1.671754e-06 7.277191e-05 11 10459228 10459786 559 + 0.890 1.305 1.504
ENSG00000133805 E026 6.7805237 0.0471322075 5.342000e-03 5.196887e-02 11 10461140 10461424 285 + 0.707 1.071 1.396
ENSG00000133805 E027 68.8639798 0.0008551452 9.859333e-03 7.952045e-02 11 10461515 10461740 226 + 1.862 1.760 -0.343
ENSG00000133805 E028 87.7458818 0.0001784340 1.378962e-02 9.900552e-02 11 10478526 10478730 205 + 1.959 1.877 -0.276
ENSG00000133805 E029 0.0000000       11 10481883 10482062 180 +      
ENSG00000133805 E030 82.2050535 0.0025770943 4.705342e-02 2.130716e-01 11 10482063 10482225 163 + 1.930 1.851 -0.266
ENSG00000133805 E031 45.0984874 0.0015835175 3.300524e-01 6.225733e-01 11 10484820 10484905 86 + 1.663 1.617 -0.157
ENSG00000133805 E032 61.1610206 0.0003144386 6.575463e-03 6.031310e-02 11 10484906 10485039 134 + 1.813 1.703 -0.373
ENSG00000133805 E033 0.7337701 0.0134785866 4.468119e-01 7.210777e-01 11 10486375 10486415 41 + 0.186 0.303 0.919
ENSG00000133805 E034 73.6672321 0.0002570530 7.966401e-04 1.256315e-02 11 10487235 10487364 130 + 1.897 1.773 -0.421
ENSG00000133805 E035 39.2815929 0.0009248196 2.182731e-01 5.047526e-01 11 10493349 10493366 18 + 1.610 1.548 -0.209
ENSG00000133805 E036 75.3210139 0.0014832173 5.137134e-06 1.925769e-04 11 10493367 10493480 114 + 1.924 1.739 -0.623
ENSG00000133805 E037 50.8906106 0.0004401305 5.962989e-05 1.539530e-03 11 10493481 10493543 63 + 1.756 1.572 -0.625
ENSG00000133805 E038 0.3714026 0.0165571865 2.666243e-01   11 10493544 10493702 159 + 0.071 0.224 1.919
ENSG00000133805 E039 31.2737651 0.0012465497 1.646165e-01 4.339039e-01 11 10494899 10494907 9 + 1.519 1.441 -0.269
ENSG00000133805 E040 103.1827459 0.0003921050 7.201365e-02 2.721211e-01 11 10494908 10495030 123 + 2.020 1.965 -0.186
ENSG00000133805 E041 162.2153666 0.0012236944 1.919924e-03 2.479626e-02 11 10495570 10495733 164 + 2.225 2.139 -0.289
ENSG00000133805 E042 2.2127358 0.0063752084 7.495728e-02 2.793602e-01 11 10496761 10496811 51 + 0.385 0.640 1.241
ENSG00000133805 E043 114.9993773 0.0001451489 1.238966e-03 1.764805e-02 11 10496812 10496938 127 + 2.079 1.985 -0.317
ENSG00000133805 E044 15.7380647 0.0067399191 2.833517e-02 1.575007e-01 11 10496939 10497437 499 + 1.135 1.312 0.627
ENSG00000133805 E045 35.5888810 0.0004019995 2.050551e-10 1.971380e-08 11 10497590 10498281 692 + 1.402 1.723 1.099
ENSG00000133805 E046 2.6737306 0.0154169245 5.598399e-01 8.006528e-01 11 10498282 10498309 28 + 0.520 0.605 0.389
ENSG00000133805 E047 7.9792478 0.0017356589 1.836589e-03 2.390314e-02 11 10498310 10498400 91 + 0.802 1.107 1.142
ENSG00000133805 E048 5.8809318 0.0023660405 3.185932e-02 1.686924e-01 11 10498401 10498436 36 + 0.722 0.958 0.919
ENSG00000133805 E049 51.2089873 0.0003596162 7.972806e-15 1.331286e-12 11 10498437 10499244 808 + 1.551 1.881 1.120
ENSG00000133805 E050 14.6742725 0.0221916668 1.513065e-02 1.057473e-01 11 10499245 10499356 112 + 1.080 1.312 0.823
ENSG00000133805 E051 72.5396714 0.0001958262 1.040525e-24 4.157014e-22 11 10499357 10500085 729 + 1.680 2.046 1.234
ENSG00000133805 E052 107.9860790 0.0001591974 1.556564e-01 4.216194e-01 11 10500086 10500184 99 + 2.004 2.048 0.149
ENSG00000133805 E053 79.4193657 0.0022564093 8.605468e-01 9.516858e-01 11 10500185 10500249 65 + 1.890 1.885 -0.018
ENSG00000133805 E054 114.1197729 0.0025267242 6.023375e-01 8.264175e-01 11 10501470 10501590 121 + 2.050 2.034 -0.056
ENSG00000133805 E055 92.9425750 0.0010629075 7.836874e-01 9.167836e-01 11 10502721 10502782 62 + 1.952 1.963 0.039
ENSG00000133805 E056 123.0766261 0.0009823967 1.720016e-01 4.447140e-01 11 10502783 10502894 112 + 2.091 2.051 -0.134
ENSG00000133805 E057 53.1314737 0.0002667868 4.252970e-04 7.689563e-03 11 10502895 10503787 893 + 1.656 1.806 0.506
ENSG00000133805 E058 59.3538601 0.0003300646 2.408043e-02 1.420907e-01 11 10504549 10504579 31 + 1.795 1.703 -0.311
ENSG00000133805 E059 89.9037717 0.0001789067 7.227530e-02 2.727085e-01 11 10504580 10504659 80 + 1.962 1.904 -0.196
ENSG00000133805 E060 972.1244599 0.0007968772 1.527820e-01 4.169712e-01 11 10505708 10507839 2132 + 2.964 2.983 0.063
ENSG00000133805 E061 4.2743567 0.0053529703 1.882921e-01 4.666388e-01 11 10507840 10508088 249 + 0.642 0.805 0.671

Help

Please Click HERE to learn more details about the results from DEXseq.