ENSG00000133816

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
MSTRG.4457.10 ENSG00000133816 No_inf pgKDN_inf MICAL2 protein_coding   46.218 60.30736 23.94434 16.96081 0.7131901 -1.332286 3.335374 3.616158 3.986353 0.8916546 0.8825765 0.1402424 0.09771667 0.072475 0.164175 0.091700 0.41196447 0.02220151 FALSE TRUE
MSTRG.4457.32 ENSG00000133816 No_inf pgKDN_inf MICAL2 protein_coding   46.218 60.30736 23.94434 16.96081 0.7131901 -1.332286 11.347705 14.598101 9.612665 1.4193221 0.4355671 -0.6022602 0.30723333 0.313175 0.402500 0.089325 0.79202025 0.02220151 FALSE TRUE
MSTRG.4457.44 ENSG00000133816 No_inf pgKDN_inf MICAL2 protein_coding   46.218 60.30736 23.94434 16.96081 0.7131901 -1.332286 4.371117 3.850683 0.000000 3.8506828 0.0000000 -8.5927122 0.10619167 0.087225 0.000000 -0.087225 1.00000000 0.02220151   FALSE
MSTRG.4457.6 ENSG00000133816 No_inf pgKDN_inf MICAL2 protein_coding   46.218 60.30736 23.94434 16.96081 0.7131901 -1.332286 3.494183 1.440572 5.539085 1.4405723 1.2001787 1.9356277 0.10998333 0.032625 0.234275 0.201650 0.02220151 0.02220151 FALSE TRUE
MSTRG.4457.9 ENSG00000133816 No_inf pgKDN_inf MICAL2 protein_coding   46.218 60.30736 23.94434 16.96081 0.7131901 -1.332286 17.504075 27.443486 0.000000 18.7267019 0.0000000 -11.4227736 0.22008333 0.312925 0.000000 -0.312925 0.82445851 0.02220151   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133816 E001 0.4904501 0.0160995907 8.094819e-01   11 12094008 12094016 9 + 0.191 0.157 -0.348
ENSG00000133816 E002 0.4904501 0.0160995907 8.094819e-01   11 12094017 12094127 111 + 0.191 0.157 -0.348
ENSG00000133816 E003 0.0000000       11 12094128 12094147 20 +      
ENSG00000133816 E004 0.0000000       11 12094148 12094224 77 +      
ENSG00000133816 E005 0.3723465 0.0164252756 7.449587e-01   11 12095544 12095629 86 + 0.106 0.157 0.652
ENSG00000133816 E006 0.1271363 0.0123098688 6.843935e-01   11 12095984 12096221 238 + 0.000 0.085 12.780
ENSG00000133816 E007 0.0000000       11 12109701 12109773 73 +      
ENSG00000133816 E008 0.6015365 0.0358176799 1.087339e-01 0.346107879 11 12110590 12110590 1 + 0.323 0.085 -2.348
ENSG00000133816 E009 0.6015365 0.0358176799 1.087339e-01 0.346107879 11 12110591 12110599 9 + 0.323 0.085 -2.348
ENSG00000133816 E010 0.7191671 0.0141113121 4.957404e-02 0.219632591 11 12110600 12110604 5 + 0.377 0.085 -2.670
ENSG00000133816 E011 0.9647243 0.0785160679 9.632988e-02 0.323239919 11 12110605 12110612 8 + 0.424 0.157 -1.933
ENSG00000133816 E012 1.2106247 0.0400277695 1.134504e-01 0.354365791 11 12110613 12110616 4 + 0.467 0.218 -1.571
ENSG00000133816 E013 2.7167156 0.0095604746 7.756227e-01 0.913805971 11 12110617 12110726 110 + 0.542 0.582 0.183
ENSG00000133816 E014 0.3717469 0.0164827234 7.448636e-01   11 12116696 12116916 221 + 0.106 0.157 0.652
ENSG00000133816 E015 0.2533610 0.0159365922 3.374531e-01   11 12121475 12121649 175 + 0.000 0.157 13.711
ENSG00000133816 E016 0.2543986 0.0160287008 3.370406e-01   11 12129356 12129411 56 + 0.000 0.157 13.710
ENSG00000133816 E017 0.0000000       11 12138388 12138389 2 +      
ENSG00000133816 E018 2.2089258 0.0072812820 6.131107e-01 0.831810392 11 12138390 12138460 71 + 0.542 0.470 -0.348
ENSG00000133816 E019 0.3646036 0.0164634638 4.445197e-01   11 12138461 12138464 4 + 0.191 0.085 -1.348
ENSG00000133816 E020 0.1268540 0.0122494631 6.845229e-01   11 12153224 12153316 93 + 0.000 0.085 12.780
ENSG00000133816 E021 0.1271363 0.0123098688 6.843935e-01   11 12161443 12161445 3 + 0.000 0.085 12.780
ENSG00000133816 E022 0.1271363 0.0123098688 6.843935e-01   11 12161446 12161532 87 + 0.000 0.085 12.780
ENSG00000133816 E023 0.0000000       11 12161533 12161576 44 +      
ENSG00000133816 E024 0.0000000       11 12161868 12162078 211 +      
ENSG00000133816 E025 3.6895683 0.1651285769 9.375743e-01 0.982087053 11 12162079 12162155 77 + 0.688 0.650 -0.158
ENSG00000133816 E026 2.9843435 0.0160573620 1.554270e-01 0.421302555 11 12162156 12162170 15 + 0.467 0.671 0.932
ENSG00000133816 E027 12.0842524 0.0142656095 9.622208e-02 0.323060373 11 12162171 12162419 249 + 1.194 1.041 -0.552
ENSG00000133816 E028 0.2346346 0.0156487492 1.698456e-01   11 12162420 12162420 1 + 0.191 0.000 -14.993
ENSG00000133816 E029 0.8805141 0.0123856309 9.643356e-02 0.323495814 11 12195945 12196200 256 + 0.106 0.362 2.237
ENSG00000133816 E030 0.8418977 0.0131921611 1.457180e-01 0.406388773 11 12197487 12197811 325 + 0.377 0.157 -1.670
ENSG00000133816 E031 14.0021073 0.0051114479 6.218231e-03 0.057932988 11 12204250 12204457 208 + 1.284 1.066 -0.777
ENSG00000133816 E032 0.0000000       11 12207725 12208022 298 +      
ENSG00000133816 E033 8.3214142 0.0207830970 2.698841e-01 0.563520282 11 12208023 12208139 117 + 1.028 0.912 -0.433
ENSG00000133816 E034 0.1271363 0.0123098688 6.843935e-01   11 12208140 12208369 230 + 0.000 0.085 12.780
ENSG00000133816 E035 6.9750190 0.0020332093 2.989951e-01 0.591877203 11 12209497 12209598 102 + 0.955 0.850 -0.398
ENSG00000133816 E036 8.3264346 0.0302032092 3.983444e-01 0.682322115 11 12213255 12213410 156 + 1.017 0.923 -0.348
ENSG00000133816 E037 7.5736011 0.0111965706 1.715333e-01 0.444094289 11 12216219 12216319 101 + 1.005 0.863 -0.534
ENSG00000133816 E038 0.6067624 0.0204432111 4.771331e-01 0.743516533 11 12216320 12216393 74 + 0.262 0.157 -0.933
ENSG00000133816 E039 15.4560489 0.0011742319 3.184714e-01 0.611239288 11 12220201 12220458 258 + 1.251 1.179 -0.256
ENSG00000133816 E040 8.4723407 0.0016124337 6.885861e-01 0.871761161 11 12221644 12221759 116 + 0.993 0.956 -0.138
ENSG00000133816 E041 8.9129174 0.0049397777 1.174076e-01 0.361961449 11 12222617 12222743 127 + 1.071 0.923 -0.546
ENSG00000133816 E042 5.8629902 0.0199442145 2.089331e-01 0.493090494 11 12223411 12223501 91 + 0.913 0.761 -0.589
ENSG00000133816 E043 0.0000000       11 12224438 12224672 235 +      
ENSG00000133816 E044 9.5393535 0.0026762721 2.032014e-01 0.485708549 11 12224673 12224820 148 + 1.081 0.966 -0.422
ENSG00000133816 E045 0.0000000       11 12225585 12225762 178 +      
ENSG00000133816 E046 5.9765559 0.0079932072 1.343899e-01 0.389687290 11 12226171 12226206 36 + 0.927 0.761 -0.643
ENSG00000133816 E047 11.2244999 0.0096618927 4.498034e-02 0.207319672 11 12226207 12226370 164 + 1.178 0.995 -0.663
ENSG00000133816 E048 9.0739248 0.0028247106 4.286277e-01 0.707111800 11 12227025 12227131 107 + 1.039 0.966 -0.270
ENSG00000133816 E049 0.1271363 0.0123098688 6.843935e-01   11 12227132 12227193 62 + 0.000 0.085 12.780
ENSG00000133816 E050 8.3378974 0.0158007100 6.437564e-01 0.849074603 11 12236177 12236245 69 + 0.993 0.945 -0.178
ENSG00000133816 E051 5.0405488 0.0037677442 9.962021e-01 1.000000000 11 12239436 12239459 24 + 0.776 0.777 0.006
ENSG00000133816 E052 12.3047101 0.0162178481 9.941650e-01 1.000000000 11 12239460 12239585 126 + 1.119 1.119 0.000
ENSG00000133816 E053 0.0000000       11 12241040 12241162 123 +      
ENSG00000133816 E054 0.0000000       11 12242182 12242213 32 +      
ENSG00000133816 E055 0.0000000       11 12242214 12242320 107 +      
ENSG00000133816 E056 0.2543986 0.0160287008 3.370406e-01   11 12242321 12242432 112 + 0.000 0.157 13.710
ENSG00000133816 E057 0.2542726 0.2499463016 3.954391e-01   11 12242671 12242772 102 + 0.000 0.157 13.390
ENSG00000133816 E058 0.2536433 0.0160073663 3.372502e-01   11 12242879 12242984 106 + 0.000 0.157 13.710
ENSG00000133816 E059 0.1170040 0.0117306821 4.206301e-01   11 12243200 12243401 202 + 0.106 0.000 -14.074
ENSG00000133816 E060 0.3703650 0.0165445180 7.454230e-01   11 12243987 12244112 126 + 0.106 0.157 0.652
ENSG00000133816 E061 1.9936181 0.0069893242 1.197156e-01 0.365655247 11 12249184 12249246 63 + 0.323 0.557 1.237
ENSG00000133816 E062 0.2373413 0.0156435933 1.700028e-01   11 12249907 12249940 34 + 0.191 0.000 -14.993
ENSG00000133816 E063 1.5897938 0.0533031718 5.180020e-01 0.773303799 11 12249941 12250273 333 + 0.467 0.362 -0.571
ENSG00000133816 E064 1.2605686 0.0110890375 2.000254e-02 0.126959980 11 12252532 12253233 702 + 0.106 0.470 2.822
ENSG00000133816 E065 6.0210738 0.0024708512 6.536794e-05 0.001658304 11 12253234 12255642 2409 + 0.506 0.986 1.974
ENSG00000133816 E066 0.8708828 0.0132456359 4.065531e-01 0.689204290 11 12255643 12255750 108 + 0.191 0.319 0.974
ENSG00000133816 E067 4.3990786 0.0044725622 1.963578e-04 0.004117559 11 12255751 12256784 1034 + 0.377 0.876 2.237
ENSG00000133816 E068 8.9981052 0.0033225759 6.313222e-01 0.841853746 11 12256785 12256841 57 + 0.968 1.014 0.172
ENSG00000133816 E069 13.6259373 0.0174162143 5.145275e-01 0.771085758 11 12256842 12256971 130 + 1.194 1.133 -0.218
ENSG00000133816 E070 0.1265070 0.0122800537 6.844290e-01   11 12256972 12257233 262 + 0.000 0.085 12.780
ENSG00000133816 E071 12.5996110 0.0020204338 8.991526e-02 0.311463692 11 12258468 12258556 89 + 1.202 1.066 -0.488
ENSG00000133816 E072 0.0000000       11 12259689 12259794 106 +      
ENSG00000133816 E073 13.3154169 0.0168145974 1.433110e-01 0.403136414 11 12259795 12259897 103 + 1.224 1.089 -0.480
ENSG00000133816 E074 47.8872997 0.0003103161 6.760941e-01 0.865839113 11 12259898 12260635 738 + 1.673 1.692 0.063
ENSG00000133816 E075 199.2960024 0.0001128326 7.394566e-02 0.277035522 11 12260636 12262479 1844 + 2.277 2.310 0.113
ENSG00000133816 E076 19.0942107 0.0062291839 8.087436e-03 0.069589624 11 12262480 12262537 58 + 1.170 1.372 0.709
ENSG00000133816 E077 23.6978662 0.0007453522 6.696544e-04 0.010957870 11 12262538 12262635 98 + 1.251 1.465 0.744
ENSG00000133816 E078 82.4352889 0.0030448128 3.788522e-02 0.187803443 11 12262636 12263559 924 + 1.869 1.948 0.266
ENSG00000133816 E079 30.7369695 0.0004665114 6.906360e-01 0.873002542 11 12263560 12263787 228 + 1.508 1.488 -0.070
ENSG00000133816 E080 0.0000000       11 12274314 12274695 382 +      
ENSG00000133816 E081 0.1187032 0.0118242505 4.206803e-01   11 12275983 12275985 3 + 0.106 0.000 -14.074
ENSG00000133816 E082 0.1187032 0.0118242505 4.206803e-01   11 12275986 12276079 94 + 0.106 0.000 -14.074
ENSG00000133816 E083 0.2444846 0.0162088246 8.500397e-01   11 12276080 12276166 87 + 0.106 0.085 -0.348
ENSG00000133816 E084 0.0000000       11 12276259 12276331 73 +      
ENSG00000133816 E085 0.1265070 0.0122800537 6.844290e-01   11 12276332 12276619 288 + 0.000 0.085 12.780
ENSG00000133816 E086 0.1265070 0.0122800537 6.844290e-01   11 12276620 12276715 96 + 0.000 0.085 12.780
ENSG00000133816 E087 0.1268540 0.0122494631 6.845229e-01   11 12280933 12280944 12 + 0.000 0.085 12.780
ENSG00000133816 E088 0.2373413 0.0156435933 1.700028e-01   11 12280945 12281099 155 + 0.191 0.000 -14.993
ENSG00000133816 E089 0.0000000       11 12286900 12287086 187 +      
ENSG00000133816 E090 0.0000000       11 12287087 12287089 3 +      
ENSG00000133816 E091 0.3724111 0.1440763074 7.744671e-01   11 12287090 12287164 75 + 0.106 0.157 0.652
ENSG00000133816 E092 0.1268540 0.0122494631 6.845229e-01   11 12287165 12287314 150 + 0.000 0.085 12.780
ENSG00000133816 E093 0.3707119 0.1449009034 7.752601e-01   11 12292143 12292297 155 + 0.106 0.157 0.653
ENSG00000133816 E094 3.1544318 0.0136724869 8.278136e-02 0.296521864 11 12293561 12294857 1297 + 0.734 0.501 -1.026
ENSG00000133816 E095 0.0000000       11 12319696 12319811 116 +      
ENSG00000133816 E096 0.1271363 0.0123098688 6.843935e-01   11 12323978 12324070 93 + 0.000 0.085 12.780
ENSG00000133816 E097 0.2457744 0.0162466541 8.508155e-01   11 12327173 12327230 58 + 0.106 0.085 -0.348
ENSG00000133816 E098 0.1186381 0.0117489009 4.208404e-01   11 12327231 12327266 36 + 0.106 0.000 -14.074
ENSG00000133816 E099 0.0000000       11 12349835 12349837 3 +      
ENSG00000133816 E100 0.3709916 0.0165071748 7.452343e-01   11 12349838 12349937 100 + 0.106 0.157 0.652
ENSG00000133816 E101 0.8518741 0.0129716245 4.889278e-01 0.752021385 11 12354784 12354857 74 + 0.323 0.218 -0.763
ENSG00000133816 E102 4.2086008 0.0089337027 4.317755e-04 0.007770230 11 12358295 12359144 850 + 0.913 0.470 -1.878

Help

Please Click HERE to learn more details about the results from DEXseq.