ENSG00000133895

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312049 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding protein_coding 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 2.4120987 2.8766615 4.3596346 2.8766615 2.5456086 0.5981107 0.14592500 0.172850 0.264925 0.092075 0.84292705 0.03344479 FALSE TRUE
ENST00000315422 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding protein_coding 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 1.4957577 0.9019568 1.4110246 0.5644428 0.3310264 0.6398941 0.08269167 0.055925 0.085325 0.029400 0.77943339 0.03344479 FALSE TRUE
ENST00000377321 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding protein_coding 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 0.9212998 0.4570124 0.9205758 0.4570124 0.6099724 0.9946627 0.05475000 0.028200 0.055425 0.027225 0.82938415 0.03344479 FALSE TRUE
ENST00000394376 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding protein_coding 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 3.1949981 3.8946081 2.6976392 1.4213677 1.5673591 -0.5281423 0.18127500 0.231500 0.160125 -0.071375 0.83308949 0.03344479 FALSE TRUE
ENST00000450708 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding protein_coding 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 3.8775769 0.8473136 5.1423325 0.8473136 2.9785213 2.5873308 0.21352500 0.052975 0.303825 0.250850 0.78109178 0.03344479 FALSE TRUE
ENST00000478548 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding retained_intron 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 1.9575966 3.4145134 0.5695666 0.1201273 0.3145929 -2.5628527 0.11171667 0.203550 0.033875 -0.169675 0.03344479 0.03344479 TRUE TRUE
ENST00000671939 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding retained_intron 17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 0.6545321 1.2847925 0.0000000 0.6193397 0.0000000 -7.0165771 0.03815833 0.077600 0.000000 -0.077600 0.03683978 0.03344479 FALSE TRUE
MSTRG.4915.9 ENSG00000133895 No_inf pgKDN_inf MEN1 protein_coding   17.56086 16.77416 16.69949 0.5128017 0.2590262 -0.006432762 0.4867236 1.4601708 0.0000000 1.4601708 0.0000000 -7.1998400 0.02665833 0.079975 0.000000 -0.079975 0.85070247 0.03344479 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000133895 E001 0.0000000       11 64803510 64803513 4 -      
ENSG00000133895 E002 0.0000000       11 64803514 64803515 2 -      
ENSG00000133895 E003 0.2340080 0.2443943748 0.2490926223   11 64803516 64803535 20 - 0.182 0.000 -10.062
ENSG00000133895 E004 0.3612703 0.1871093907 0.5467359956   11 64803536 64803539 4 - 0.182 0.090 -1.177
ENSG00000133895 E005 0.9873857 0.0186550026 0.6095834737 0.830174629 11 64803540 64803541 2 - 0.251 0.333 0.559
ENSG00000133895 E006 2.3283333 0.0916240310 0.9756983691 0.995767325 11 64803542 64803577 36 - 0.524 0.519 -0.025
ENSG00000133895 E007 2.9448196 0.1229970791 0.8592061089 0.950996331 11 64803578 64803584 7 - 0.587 0.601 0.064
ENSG00000133895 E008 3.1903768 0.1262789342 0.8941998964 0.965003873 11 64803585 64803593 9 - 0.615 0.626 0.045
ENSG00000133895 E009 96.1756043 0.0028916570 0.6491508581 0.852126035 11 64803594 64804489 896 - 1.989 1.982 -0.023
ENSG00000133895 E010 26.1726638 0.0005935835 0.7629181594 0.907470801 11 64804490 64804710 221 - 1.419 1.442 0.080
ENSG00000133895 E011 14.0561892 0.0013000952 0.1596791646 0.427146913 11 64804711 64804795 85 - 1.227 1.128 -0.354
ENSG00000133895 E012 6.1353607 0.0027510388 0.8359169225 0.941137159 11 64804796 64804807 12 - 0.860 0.844 -0.063
ENSG00000133895 E013 6.0058350 0.0024989453 0.7324710985 0.893679363 11 64804808 64804816 9 - 0.860 0.829 -0.119
ENSG00000133895 E014 17.9082423 0.0007775237 0.7287357497 0.891847000 11 64805034 64805198 165 - 1.284 1.267 -0.060
ENSG00000133895 E015 12.6343713 0.0034077273 0.8272292350 0.937482180 11 64805635 64805770 136 - 1.139 1.128 -0.038
ENSG00000133895 E016 1.0158016 0.0114487641 0.0037353143 0.040486423 11 64805771 64805887 117 - 0.000 0.453 13.689
ENSG00000133895 E017 2.7571272 0.0052836058 0.0056460941 0.054072406 11 64805888 64806013 126 - 0.310 0.711 1.992
ENSG00000133895 E018 2.1305085 0.0249945752 0.0168293274 0.113119759 11 64806014 64806082 69 - 0.251 0.625 2.044
ENSG00000133895 E019 3.7653479 0.0042075527 0.0006120808 0.010207782 11 64806083 64806231 149 - 0.362 0.829 2.144
ENSG00000133895 E020 12.6294795 0.0011926713 0.6827010524 0.868584822 11 64806232 64806368 137 - 1.147 1.120 -0.094
ENSG00000133895 E021 2.1470049 0.0065878732 0.0002146215 0.004426537 11 64806369 64807010 642 - 0.100 0.670 3.822
ENSG00000133895 E022 8.5692314 0.0019780357 0.4145105621 0.694702236 11 64807011 64807098 88 - 1.016 0.946 -0.261
ENSG00000133895 E023 0.3726934 0.0167808530 0.6724703915   11 64807099 64807178 80 - 0.100 0.164 0.822
ENSG00000133895 E024 5.8986843 0.0074369184 0.9224933537 0.976102003 11 64807179 64807219 41 - 0.828 0.844 0.063
ENSG00000133895 E025 12.3146282 0.0112094619 0.5267068198 0.778946657 11 64807552 64807680 129 - 1.086 1.150 0.228
ENSG00000133895 E026 1.3980616 0.0768433593 0.0012011048 0.017215091 11 64807681 64807890 210 - 0.000 0.548 13.914
ENSG00000133895 E027 7.2487491 0.0019970182 0.9061358794 0.970038954 11 64807891 64807904 14 - 0.905 0.922 0.067
ENSG00000133895 E028 9.7008430 0.0025232226 0.9565935263 0.989705987 11 64807905 64807995 91 - 1.027 1.028 0.005
ENSG00000133895 E029 10.0590193 0.0198112354 0.7362644803 0.895340282 11 64807996 64808099 104 - 1.058 1.028 -0.108
ENSG00000133895 E030 0.1176306 0.0119589600 0.4682053580   11 64809650 64809664 15 - 0.100 0.000 -11.960
ENSG00000133895 E031 4.5274660 0.0237644666 0.5896640080 0.818313571 11 64809665 64809669 5 - 0.774 0.711 -0.256
ENSG00000133895 E032 23.4626319 0.0006644783 0.0432431864 0.202806784 11 64809670 64810132 463 - 1.444 1.332 -0.389
ENSG00000133895 E033 0.4985363 0.0152918380 0.3910257444   11 64810133 64810267 135 - 0.100 0.228 1.407
ENSG00000133895 E034 2.4701582 0.0082838045 0.5602802458 0.800905242 11 64810268 64810457 190 - 0.489 0.575 0.407
ENSG00000133895 E035 0.5002991 0.0297934248 0.3940630768 0.678839658 11 64810458 64810513 56 - 0.100 0.228 1.407
ENSG00000133895 E036 1.3433688 0.1995284888 0.6233131638 0.837797321 11 64810514 64810525 12 - 0.409 0.333 -0.442
ENSG00000133895 E037 1.3333928 0.0909643104 0.3131023504 0.606394074 11 64810526 64810608 83 - 0.451 0.283 -0.985
ENSG00000133895 E038 0.0000000       11 64810630 64810686 57 -      
ENSG00000133895 E039 0.0000000       11 64810814 64810905 92 -      
ENSG00000133895 E040 0.0000000       11 64810906 64811033 128 -      
ENSG00000133895 E041 0.0000000       11 64811034 64811294 261 -      

Help

Please Click HERE to learn more details about the results from DEXseq.