ENSG00000134186

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370025 ENSG00000134186 No_inf pgKDN_inf PRPF38B protein_coding protein_coding 43.31836 51.14526 40.94702 0.8881503 2.146479 -0.3207719 16.467374 13.519010 18.6139734 0.8353143 2.4018726 0.4611046 0.39340000 0.264125 0.457950 0.193825 1.866170e-01 3.701911e-10 FALSE TRUE
ENST00000485810 ENSG00000134186 No_inf pgKDN_inf PRPF38B protein_coding protein_coding_CDS_not_defined 43.31836 51.14526 40.94702 0.8881503 2.146479 -0.3207719 9.621393 14.455594 7.8982177 0.9764095 0.5628329 -0.8712011 0.21565833 0.282125 0.195225 -0.086900 4.880187e-01 3.701911e-10 FALSE FALSE
MSTRG.1472.14 ENSG00000134186 No_inf pgKDN_inf PRPF38B protein_coding   43.31836 51.14526 40.94702 0.8881503 2.146479 -0.3207719 2.698683 3.666399 4.1006436 1.2775431 3.2921109 0.1610711 0.05649167 0.071000 0.089900 0.018900 8.462210e-01 3.701911e-10 FALSE TRUE
MSTRG.1472.4 ENSG00000134186 No_inf pgKDN_inf PRPF38B protein_coding   43.31836 51.14526 40.94702 0.8881503 2.146479 -0.3207719 4.273749 3.625094 5.1426676 2.0991414 1.8820039 0.5033270 0.10386667 0.069975 0.132500 0.062525 7.998778e-01 3.701911e-10 FALSE TRUE
MSTRG.1472.6 ENSG00000134186 No_inf pgKDN_inf PRPF38B protein_coding   43.31836 51.14526 40.94702 0.8881503 2.146479 -0.3207719 3.142605 8.430613 0.0000000 1.3742476 0.0000000 -9.7212040 0.06372500 0.165200 0.000000 -0.165200 3.701911e-10 3.701911e-10 FALSE TRUE
MSTRG.1472.8 ENSG00000134186 No_inf pgKDN_inf PRPF38B protein_coding   43.31836 51.14526 40.94702 0.8881503 2.146479 -0.3207719 2.630550 4.051926 0.8780187 1.3687231 0.8780187 -2.1935020 0.06010833 0.080550 0.022900 -0.057650 4.012620e-01 3.701911e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134186 E001 0.1265070 1.222645e-02 7.833313e-01   1 108692305 108692309 5 + 0.000 0.081 8.593
ENSG00000134186 E002 0.2441377 1.619730e-02 7.739498e-01   1 108692310 108692319 10 + 0.112 0.081 -0.528
ENSG00000134186 E003 0.4886223 5.532263e-02 7.223087e-01   1 108692320 108692322 3 + 0.201 0.148 -0.528
ENSG00000134186 E004 0.8517450 1.516775e-01 4.623178e-01 7.327532e-01 1 108692323 108692323 1 + 0.338 0.207 -0.943
ENSG00000134186 E005 0.9693756 2.770757e-01 4.044136e-01 6.871556e-01 1 108692324 108692326 3 + 0.393 0.207 -1.265
ENSG00000134186 E006 1.3506283 1.422244e-01 8.546507e-01 9.487343e-01 1 108692327 108692331 5 + 0.393 0.347 -0.265
ENSG00000134186 E007 4.2055611 5.687414e-03 5.130281e-01 7.699919e-01 1 108692332 108692340 9 + 0.656 0.739 0.347
ENSG00000134186 E008 62.6376376 2.396612e-03 4.152192e-01 6.953281e-01 1 108692341 108692867 527 + 1.813 1.780 -0.111
ENSG00000134186 E009 4.6855992 3.660900e-03 8.641511e-01 9.529550e-01 1 108693590 108693642 53 + 0.733 0.755 0.089
ENSG00000134186 E010 26.6105778 6.749672e-03 8.830991e-02 3.082189e-01 1 108695702 108695770 69 + 1.495 1.384 -0.381
ENSG00000134186 E011 3.2910704 7.067484e-02 1.419638e-04 3.161302e-03 1 108695771 108695780 10 + 0.112 0.785 4.116
ENSG00000134186 E012 43.7348157 4.952520e-04 6.030374e-02 2.464410e-01 1 108696043 108696194 152 + 1.689 1.606 -0.284
ENSG00000134186 E013 24.3581495 1.024821e-03 3.851162e-01 6.712126e-01 1 108696277 108696337 61 + 1.424 1.373 -0.177
ENSG00000134186 E014 33.0224896 3.272147e-03 1.303331e-01 3.829806e-01 1 108696338 108696739 402 + 1.466 1.555 0.305
ENSG00000134186 E015 71.6324641 1.618025e-03 1.112749e-08 7.855366e-07 1 108696740 108697699 960 + 1.695 1.928 0.789
ENSG00000134186 E016 7.4062048 2.786439e-02 6.366279e-04 1.051313e-02 1 108697700 108697728 29 + 0.595 1.041 1.764
ENSG00000134186 E017 21.3316033 7.373711e-04 8.519274e-06 2.981690e-04 1 108697729 108697863 135 + 1.125 1.436 1.091
ENSG00000134186 E018 13.1341704 1.049838e-03 1.691574e-05 5.350929e-04 1 108697864 108697946 83 + 0.873 1.253 1.388
ENSG00000134186 E019 18.2287623 7.774455e-04 6.191484e-02 2.500236e-01 1 108697947 108698017 71 + 1.188 1.322 0.472
ENSG00000134186 E020 41.0269905 3.795077e-04 6.003439e-03 5.648371e-02 1 108698018 108698603 586 + 1.527 1.661 0.459
ENSG00000134186 E021 87.1471154 1.979752e-04 8.064441e-01 9.284278e-01 1 108698604 108698827 224 + 1.939 1.932 -0.021
ENSG00000134186 E022 122.0335071 2.416648e-04 2.309247e-01 5.193824e-01 1 108699162 108699466 305 + 2.098 2.067 -0.103
ENSG00000134186 E023 83.6744769 1.855270e-04 1.183114e-02 8.972133e-02 1 108699467 108699570 104 + 1.964 1.884 -0.269
ENSG00000134186 E024 552.2098597 5.528205e-05 3.239144e-04 6.195035e-03 1 108699571 108702928 3358 + 2.753 2.719 -0.112

Help

Please Click HERE to learn more details about the results from DEXseq.