ENSG00000134262

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000256658 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding protein_coding 17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 1.9418712 0.3370168 2.6796833 0.3370168 1.5471795 2.9543591 0.10185000 0.022375 0.129275 0.106900 0.81846666 0.03010065 FALSE TRUE
ENST00000369567 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding protein_coding 17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 1.4921872 1.1310404 1.9364226 0.5249630 1.2103525 0.7704751 0.08815833 0.078275 0.102050 0.023775 0.91292279 0.03010065 FALSE TRUE
ENST00000460653 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding protein_coding_CDS_not_defined 17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 1.4567751 0.4380450 2.8473613 0.4380450 0.4099908 2.6729678 0.06896667 0.029100 0.142200 0.113100 0.14310982 0.03010065   FALSE
ENST00000472122 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding protein_coding_CDS_not_defined 17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 1.6137472 3.0189119 0.6436185 0.4253736 0.4716068 -2.2122788 0.10810833 0.223100 0.032825 -0.190275 0.05957301 0.03010065 FALSE FALSE
ENST00000479801 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding protein_coding_CDS_not_defined 17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 1.2990395 0.0000000 1.3840352 0.0000000 1.3840352 7.1231232 0.05408333 0.000000 0.064100 0.064100 0.87774818 0.03010065 FALSE FALSE
MSTRG.1589.4 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding   17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 1.1778125 0.4676099 2.6526705 0.4676099 1.6806431 2.4789694 0.05918333 0.031050 0.132950 0.101900 0.82706789 0.03010065 FALSE TRUE
MSTRG.1589.5 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding   17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 2.6360909 3.9979756 0.7349541 0.6149077 0.7349541 -2.4276504 0.17770000 0.307500 0.039750 -0.267750 0.03010065 0.03010065 TRUE TRUE
MSTRG.1589.8 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding   17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 0.5605619 0.8606933 0.1390958 0.2930480 0.1390958 -2.5459255 0.03760833 0.064600 0.006950 -0.057650 0.30071108 0.03010065 TRUE TRUE
MSTRG.1589.9 ENSG00000134262 No_inf pgKDN_inf AP4B1 protein_coding   17.97819 13.47419 20.00164 0.765291 0.6332598 0.5695711 3.2140230 2.4620927 4.1392436 0.9360410 1.4664393 0.7471155 0.18623333 0.186950 0.207900 0.020950 1.00000000 0.03010065 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134262 E001 1.4415181 0.0093137186 0.0963237590 0.323239919 1 113894194 113894747 554 - 0.496 0.245 -1.489
ENSG00000134262 E002 0.4814816 0.0154874007 0.3465354812   1 113894748 113894900 153 - 0.233 0.098 -1.489
ENSG00000134262 E003 0.3727544 0.0169963692 0.5481016796   1 113894901 113894910 10 - 0.092 0.178 1.096
ENSG00000134262 E004 1.2088880 0.0123930484 0.2385434532 0.527507759 1 113894911 113895055 145 - 0.424 0.245 -1.127
ENSG00000134262 E005 0.2362687 0.0157981253 0.2624596190   1 113895056 113895059 4 - 0.168 0.000 -11.215
ENSG00000134262 E006 28.5756576 0.0010807319 0.4137658957 0.694349387 1 113895060 113895492 433 - 1.489 1.452 -0.127
ENSG00000134262 E007 1.0795863 0.0112492023 0.1048735957 0.338616649 1 113895493 113895756 264 - 0.424 0.178 -1.712
ENSG00000134262 E008 27.1865984 0.0005659994 0.7492742299 0.901177850 1 113895757 113896038 282 - 1.440 1.460 0.070
ENSG00000134262 E009 0.5074127 0.0162776164 0.0391417294 0.191562964 1 113896039 113896044 6 - 0.000 0.304 11.290
ENSG00000134262 E010 2.2596299 0.0067713798 0.0022603249 0.028024911 1 113896045 113896257 213 - 0.233 0.681 2.418
ENSG00000134262 E011 11.7246583 0.0012461293 0.5792791874 0.812093047 1 113896258 113896348 91 - 1.124 1.084 -0.145
ENSG00000134262 E012 11.4880249 0.0030193845 0.8918056040 0.964077981 1 113896349 113896465 117 - 1.100 1.093 -0.027
ENSG00000134262 E013 7.0168166 0.0020597392 0.2466390268 0.537290139 1 113896466 113897839 1374 - 0.840 0.959 0.452
ENSG00000134262 E014 2.0676584 0.0363761046 0.5789015688 0.811808793 1 113897840 113897943 104 - 0.527 0.443 -0.419
ENSG00000134262 E015 0.0000000       1 113897944 113897975 32 -      
ENSG00000134262 E016 0.8612261 0.0157307789 0.6539188869 0.854679502 1 113898718 113898763 46 - 0.233 0.304 0.511
ENSG00000134262 E017 0.7533168 0.0134871056 0.0800710923 0.290476337 1 113898764 113898801 38 - 0.092 0.355 2.418
ENSG00000134262 E018 1.4490048 0.0094276509 0.2893375859 0.582944126 1 113899128 113899352 225 - 0.462 0.304 -0.904
ENSG00000134262 E019 0.0000000       1 113899904 113899941 38 -      
ENSG00000134262 E020 0.0000000       1 113899942 113899987 46 -      
ENSG00000134262 E021 0.0000000       1 113899988 113900061 74 -      
ENSG00000134262 E022 0.0000000       1 113900062 113900230 169 -      
ENSG00000134262 E023 0.0000000       1 113900231 113900269 39 -      
ENSG00000134262 E024 0.0000000       1 113900270 113900330 61 -      
ENSG00000134262 E025 0.0000000       1 113900331 113900400 70 -      
ENSG00000134262 E026 6.5928527 0.0025012512 0.5396342775 0.787996078 1 113901236 113901383 148 - 0.909 0.850 -0.226
ENSG00000134262 E027 9.6491944 0.0016860704 0.5866188492 0.816777701 1 113901755 113901885 131 - 1.048 1.005 -0.161
ENSG00000134262 E028 4.1358036 0.0138664932 0.0001280812 0.002900213 1 113901886 113902257 372 - 0.384 0.894 2.266
ENSG00000134262 E029 8.5699920 0.0018571661 0.8076428990 0.929009813 1 113902638 113902734 97 - 0.968 0.994 0.096
ENSG00000134262 E030 6.4407780 0.0029757003 0.1867825829 0.464857728 1 113902735 113902862 128 - 0.933 0.800 -0.512
ENSG00000134262 E031 1.8320176 0.0076670010 0.8840821207 0.961044007 1 113904605 113904793 189 - 0.462 0.443 -0.097
ENSG00000134262 E032 0.9792923 0.0123151858 0.9374124571 0.982087053 1 113904794 113904844 51 - 0.289 0.304 0.096
ENSG00000134262 E033 0.0000000       1 113904921 113904941 21 -      
ENSG00000134262 E034 0.3731018 0.0166375888 0.5485419774   1 113904942 113905201 260 - 0.092 0.178 1.096

Help

Please Click HERE to learn more details about the results from DEXseq.