ENSG00000134294

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000256689 ENSG00000134294 No_inf pgKDN_inf SLC38A2 protein_coding protein_coding 85.64612 64.04408 99.01242 2.114792 0.6282361 0.6284646 79.56736 54.85186 95.68248 0.6599932 0.794843 0.802602 0.9216 0.8589 0.966375 0.107475 3.25164e-06 3.25164e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134294 E001 134.9300906 1.687665e-04 0.4435511955 0.71834272 12 46358188 46358480 293 - 2.135 2.115 -0.066
ENSG00000134294 E002 623.1834598 4.747541e-05 0.0068178461 0.06199860 12 46358481 46359384 904 - 2.777 2.806 0.098
ENSG00000134294 E003 659.5029914 4.471156e-05 0.2140245668 0.49918212 12 46359385 46360959 1575 - 2.808 2.821 0.044
ENSG00000134294 E004 73.8558561 1.072668e-03 0.7474012678 0.90028883 12 46360960 46361110 151 - 1.873 1.861 -0.040
ENSG00000134294 E005 30.4445261 2.427171e-03 0.3963997639 0.68111201 12 46361111 46361117 7 - 1.511 1.462 -0.168
ENSG00000134294 E006 53.7517229 3.159819e-04 0.3135910748 0.60675232 12 46361118 46361209 92 - 1.749 1.707 -0.142
ENSG00000134294 E007 2.6055642 9.359977e-02 0.0390225495 0.19128249 12 46361853 46362283 431 - 0.379 0.717 1.597
ENSG00000134294 E008 26.4604048 2.542726e-03 0.5275529875 0.77947135 12 46362284 46362289 6 - 1.448 1.410 -0.133
ENSG00000134294 E009 33.6580394 7.381080e-04 0.7817063706 0.91603295 12 46362290 46362324 35 - 1.540 1.525 -0.049
ENSG00000134294 E010 34.1988499 4.478436e-04 0.2599631847 0.55259079 12 46362325 46362381 57 - 1.564 1.505 -0.200
ENSG00000134294 E011 0.7423916 3.709648e-02 0.1961665241 0.47683637 12 46362382 46362493 112 - 0.146 0.343 1.596
ENSG00000134294 E012 66.9314318 2.509132e-04 0.8360618435 0.94115752 12 46362494 46362638 145 - 1.829 1.822 -0.025
ENSG00000134294 E013 1.8488280 8.308766e-03 0.1210137685 0.36814014 12 46362639 46362904 266 - 0.341 0.569 1.182
ENSG00000134294 E014 48.3278547 4.394901e-04 0.5785012796 0.81164443 12 46363021 46363114 94 - 1.697 1.673 -0.082
ENSG00000134294 E015 27.5787265 5.064104e-04 0.7480247485 0.90057518 12 46363115 46363145 31 - 1.457 1.439 -0.063
ENSG00000134294 E016 49.5878721 2.787514e-04 0.2295119491 0.51810707 12 46363726 46363826 101 - 1.676 1.727 0.176
ENSG00000134294 E017 35.9911831 1.136292e-03 0.9868358004 0.99954777 12 46363924 46364003 80 - 1.561 1.563 0.004
ENSG00000134294 E018 33.2793975 4.289669e-04 0.7035269156 0.87941821 12 46364389 46364441 53 - 1.537 1.517 -0.068
ENSG00000134294 E019 50.7269177 7.685810e-04 0.6981747381 0.87685371 12 46364442 46364556 115 - 1.700 1.717 0.058
ENSG00000134294 E020 2.3762840 6.472547e-03 0.0005956297 0.01001705 12 46364557 46364641 85 - 0.254 0.742 2.504
ENSG00000134294 E021 0.8512173 1.476919e-02 0.8712299386 0.95574623 12 46364642 46364643 2 - 0.254 0.279 0.182
ENSG00000134294 E022 39.2995832 1.198857e-03 0.0131429459 0.09603734 12 46364644 46364702 59 - 1.647 1.521 -0.430
ENSG00000134294 E023 0.9965455 2.132404e-02 0.0475525539 0.21438598 12 46364703 46364832 130 - 0.146 0.448 2.182
ENSG00000134294 E024 41.0600236 3.395839e-04 0.0752923839 0.28011447 12 46365107 46365189 83 - 1.651 1.566 -0.290
ENSG00000134294 E025 1.6134089 7.665855e-02 0.0580764696 0.24122421 12 46365190 46365307 118 - 0.254 0.569 1.767
ENSG00000134294 E026 34.8932361 5.023946e-04 0.9732910854 0.99513672 12 46366864 46366945 82 - 1.549 1.548 -0.005
ENSG00000134294 E027 35.6035868 1.641934e-03 0.7605664677 0.90634636 12 46367076 46367168 93 - 1.564 1.548 -0.054
ENSG00000134294 E028 25.8110562 5.829256e-03 0.2723308860 0.56606790 12 46367267 46367340 74 - 1.451 1.378 -0.253
ENSG00000134294 E029 2.3725125 1.630266e-02 0.0007802357 0.01238047 12 46367341 46367410 70 - 0.254 0.742 2.504
ENSG00000134294 E030 32.1067446 1.195783e-03 0.1241091367 0.37324089 12 46370512 46370627 116 - 1.547 1.462 -0.290
ENSG00000134294 E031 16.3324773 3.965557e-03 0.5463405684 0.79213737 12 46370776 46370798 23 - 1.213 1.259 0.163
ENSG00000134294 E032 22.8388883 5.987653e-04 0.7832510179 0.91658371 12 46370799 46370857 59 - 1.378 1.361 -0.059
ENSG00000134294 E033 0.2435110 1.646455e-02 0.7481760101   12 46370858 46371177 320 - 0.079 0.114 0.592
ENSG00000134294 E034 51.1904679 2.914613e-04 0.0081726032 0.07009948 12 46371178 46371379 202 - 1.755 1.641 -0.388
ENSG00000134294 E035 0.0000000       12 46371380 46371433 54 -      
ENSG00000134294 E036 0.0000000       12 46372321 46372508 188 -      
ENSG00000134294 E037 40.1854829 3.532356e-04 0.0306283143 0.16465945 12 46372509 46372773 265 - 1.649 1.544 -0.358

Help

Please Click HERE to learn more details about the results from DEXseq.