ENSG00000134321

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000382040 ENSG00000134321 No_inf pgKDN_inf RSAD2 protein_coding protein_coding 2.915711 2.020601 1.310087 0.2548604 0.1678123 -0.6212739 2.01728898 0.2324061 1.1853916 0.2324061 0.2214486 2.301985 0.63216667 0.160625 0.87675 0.716125 0.04540971 0.04540971 FALSE TRUE
ENST00000442639 ENSG00000134321 No_inf pgKDN_inf RSAD2 protein_coding protein_coding 2.915711 2.020601 1.310087 0.2548604 0.1678123 -0.6212739 0.26989996 0.5453809 0.0000000 0.3163846 0.0000000 -5.795406 0.09425000 0.237225 0.00000 -0.237225 0.57804457 0.04540971 FALSE TRUE
ENST00000474872 ENSG00000134321 No_inf pgKDN_inf RSAD2 protein_coding protein_coding_CDS_not_defined 2.915711 2.020601 1.310087 0.2548604 0.1678123 -0.6212739 0.13888586 0.4166576 0.0000000 0.4166576 0.0000000 -5.415007 0.05179167 0.155375 0.00000 -0.155375 0.88126102 0.04540971   FALSE
ENST00000489749 ENSG00000134321 No_inf pgKDN_inf RSAD2 protein_coding retained_intron 2.915711 2.020601 1.310087 0.2548604 0.1678123 -0.6212739 0.09779584 0.2933875 0.0000000 0.1714990 0.0000000 -4.923090 0.04971667 0.149150 0.00000 -0.149150 0.67694888 0.04540971 FALSE TRUE
ENST00000679863 ENSG00000134321 No_inf pgKDN_inf RSAD2 protein_coding nonsense_mediated_decay 2.915711 2.020601 1.310087 0.2548604 0.1678123 -0.6212739 0.31586413 0.4389909 0.1246953 0.1828897 0.0600669 -1.736987 0.14708333 0.248500 0.12325 -0.125250 0.87546241 0.04540971 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134321 E001 0.0000000       2 6865557 6865635 79 +      
ENSG00000134321 E002 0.0000000       2 6865636 6865726 91 +      
ENSG00000134321 E003 0.0000000       2 6865727 6865789 63 +      
ENSG00000134321 E004 0.0000000       2 6865790 6865805 16 +      
ENSG00000134321 E005 0.0000000       2 6865806 6865889 84 +      
ENSG00000134321 E006 0.0000000       2 6865890 6865959 70 +      
ENSG00000134321 E007 0.2541163 0.01706342 0.372882136   2 6865960 6866045 86 + 0.000 0.152 10.610
ENSG00000134321 E008 3.6464299 0.18291936 0.018244266 0.11928552 2 6876716 6877776 1061 + 0.331 0.795 2.198
ENSG00000134321 E009 1.0967943 0.01618633 0.430181677 0.70817827 2 6877777 6878022 246 + 0.385 0.265 -0.767
ENSG00000134321 E010 0.7061646 0.01829783 0.003045685 0.03489823 2 6878023 6878080 58 + 0.434 0.000 -14.712
ENSG00000134321 E011 0.2346346 0.01651075 0.150468450   2 6878081 6878146 66 + 0.196 0.000 -13.578
ENSG00000134321 E012 0.0000000       2 6878794 6879041 248 +      
ENSG00000134321 E013 0.0000000       2 6882926 6883081 156 +      
ENSG00000134321 E014 1.1074099 0.01326940 0.890929457 0.96365730 2 6883371 6883532 162 + 0.331 0.311 -0.124
ENSG00000134321 E015 0.2539903 0.01697356 0.373192944   2 6883533 6883830 298 + 0.000 0.152 12.365
ENSG00000134321 E016 1.2166711 0.01404850 0.253374480 0.54491982 2 6886935 6887130 196 + 0.434 0.265 -1.031
ENSG00000134321 E017 0.7353155 0.01583398 0.699634057 0.87759758 2 6887131 6887164 34 + 0.269 0.212 -0.446
ENSG00000134321 E018 1.1264145 0.01399847 0.202864407 0.48541654 2 6890176 6890325 150 + 0.196 0.392 1.362
ENSG00000134321 E019 0.5086713 0.19147204 0.129661584 0.38201884 2 6893671 6893703 33 + 0.000 0.265 13.047
ENSG00000134321 E020 17.9239284 0.02593274 0.232687577 0.52130459 2 6895778 6898239 2462 + 1.304 1.245 -0.208

Help

Please Click HERE to learn more details about the results from DEXseq.