ENSG00000134375

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367287 ENSG00000134375 No_inf pgKDN_inf TIMM17A protein_coding protein_coding 62.52988 41.51541 74.88876 1.385871 1.971622 0.8509476 52.886447 29.395470 66.523484 1.3443428 1.512834 1.177996 0.8266583 0.70865 0.889450 0.180800 0.006682597 0.006682597 FALSE TRUE
ENST00000484647 ENSG00000134375 No_inf pgKDN_inf TIMM17A protein_coding protein_coding_CDS_not_defined 62.52988 41.51541 74.88876 1.385871 1.971622 0.8509476 5.914417 8.232065 3.957006 0.5695013 1.031542 -1.054955 0.1092833 0.19800 0.052175 -0.145825 0.017511567 0.006682597   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134375 E001 0.000000       1 201955503 201955505 3 +      
ENSG00000134375 E002 0.000000       1 201955506 201955509 4 +      
ENSG00000134375 E003 17.742831 0.0007782862 0.131839246 0.38518325 1 201955510 201955552 43 + 1.296 1.190 -0.373
ENSG00000134375 E004 45.452144 0.0003234685 0.983705870 0.99869026 1 201957281 201957380 100 + 1.652 1.654 0.008
ENSG00000134375 E005 44.224317 0.0003503102 0.855988814 0.94936973 1 201957511 201957574 64 + 1.643 1.638 -0.017
ENSG00000134375 E006 4.311397 0.0045803934 0.004153512 0.04363744 1 201957575 201958028 454 + 0.550 0.898 1.439
ENSG00000134375 E007 5.090371 0.0034423233 0.993881956 1.00000000 1 201958617 201958908 292 + 0.772 0.774 0.006
ENSG00000134375 E008 5.914823 0.0025903212 0.001657149 0.02208843 1 201962216 201962803 588 + 0.667 1.009 1.340
ENSG00000134375 E009 1.837306 0.0084109642 0.171791092 0.44442540 1 201962804 201962924 121 + 0.357 0.560 1.047
ENSG00000134375 E010 6.879935 0.1996516967 0.139150285 0.39664561 1 201962925 201963615 691 + 0.744 1.049 1.167
ENSG00000134375 E011 66.940329 0.0003228094 0.355742200 0.64551357 1 201963616 201963744 129 + 1.829 1.798 -0.103
ENSG00000134375 E012 66.569472 0.0002398359 0.808623952 0.92935967 1 201965433 201965543 111 + 1.811 1.823 0.040
ENSG00000134375 E013 245.154860 0.0001146384 0.333925001 0.62584394 1 201969469 201970664 1196 + 2.381 2.370 -0.037

Help

Please Click HERE to learn more details about the results from DEXseq.