ENSG00000134444

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000587198 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding retained_intron 22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 4.725183 9.1936939 2.3798284 2.6669299 1.4396470 -1.94530595 0.19646667 0.306625 0.168625 -0.138000 0.5952575 0.0143795 TRUE TRUE
ENST00000587725 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding non_stop_decay 22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 1.620076 1.7021597 1.3093565 0.6793048 0.4445245 -0.37598276 0.08137500 0.063425 0.083700 0.020275 0.9133774 0.0143795 FALSE TRUE
ENST00000587764 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding protein_coding_CDS_not_defined 22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 5.448284 4.4415376 4.6883652 1.6959169 1.6978327 0.07785513 0.25958333 0.167975 0.276150 0.108175 0.8512894 0.0143795 FALSE FALSE
ENST00000644646 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding protein_coding 22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 1.245410 0.6090474 2.7118126 0.2102064 0.2848553 2.13644604 0.07182500 0.021650 0.174850 0.153200 0.0143795 0.0143795 FALSE TRUE
MSTRG.14064.12 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding   22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 2.546930 2.5354180 1.8224786 1.1686037 0.8372333 -0.47410623 0.11233333 0.087800 0.107375 0.019575 0.9713027 0.0143795 FALSE TRUE
MSTRG.14064.15 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding   22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 1.219747 1.4606760 0.3962020 0.2096777 0.2832150 -1.85621037 0.05361667 0.053650 0.022950 -0.030700 0.6450785 0.0143795 FALSE TRUE
MSTRG.14064.4 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding   22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 1.202684 1.6733962 0.5760657 0.4519030 0.2757692 -1.52224032 0.05090833 0.056775 0.034600 -0.022175 0.8348852 0.0143795 FALSE TRUE
MSTRG.14064.7 ENSG00000134444 No_inf pgKDN_inf RELCH protein_coding   22.0118 28.4714 15.94603 2.37604 1.043373 -0.8359181 1.638775 2.9427391 0.7422063 0.4273898 0.3871409 -1.97285367 0.07090000 0.106025 0.044875 -0.061150 0.5119500 0.0143795 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134444 E001 0.0000000       18 62187255 62187257 3 +      
ENSG00000134444 E002 0.0000000       18 62187258 62187273 16 +      
ENSG00000134444 E003 0.0000000       18 62187274 62187275 2 +      
ENSG00000134444 E004 0.3703650 0.0166954736 0.867668247   18 62187276 62187290 15 + 0.113 0.147 0.435
ENSG00000134444 E005 14.0900795 0.0013596788 0.039736088 0.19319679 18 62187291 62188031 741 + 1.255 1.103 -0.540
ENSG00000134444 E006 4.5195931 0.0094755212 0.096485655 0.32351698 18 62211153 62211242 90 + 0.842 0.645 -0.800
ENSG00000134444 E007 0.0000000       18 62220860 62221036 177 +      
ENSG00000134444 E008 3.4317064 0.0065521514 0.295047640 0.58834989 18 62221037 62221108 72 + 0.713 0.582 -0.565
ENSG00000134444 E009 2.5664205 0.0087312114 0.262536024 0.55538803 18 62221219 62221274 56 + 0.631 0.479 -0.703
ENSG00000134444 E010 6.7660117 0.0022455844 0.592812541 0.82050315 18 62221384 62221497 114 + 0.911 0.860 -0.196
ENSG00000134444 E011 10.7471553 0.0485443134 0.957010700 0.98975055 18 62227289 62227492 204 + 1.046 1.067 0.075
ENSG00000134444 E012 8.8132540 0.0030186886 0.055472176 0.23465539 18 62227598 62227689 92 + 1.080 0.905 -0.646
ENSG00000134444 E013 8.9694988 0.0016922692 0.375143546 0.66272191 18 62228305 62228384 80 + 1.034 0.957 -0.288
ENSG00000134444 E014 6.0364596 0.0069741758 0.926267658 0.97784885 18 62228385 62228439 55 + 0.842 0.835 -0.029
ENSG00000134444 E015 8.8833001 0.0018061568 0.968286331 0.99364123 18 62228440 62228598 159 + 0.984 0.985 0.003
ENSG00000134444 E016 5.1523523 0.0504810534 0.368320146 0.65678036 18 62231194 62231269 76 + 0.842 0.735 -0.428
ENSG00000134444 E017 2.9662711 0.0524360983 0.869627247 0.95513414 18 62232332 62232343 12 + 0.566 0.604 0.172
ENSG00000134444 E018 5.1911208 0.0028880374 0.797206605 0.92344747 18 62232344 62232427 84 + 0.761 0.795 0.135
ENSG00000134444 E019 2.6119323 0.0052555258 0.277042249 0.57045763 18 62234880 62235479 600 + 0.445 0.604 0.757
ENSG00000134444 E020 0.2451451 0.0168543980 0.753922882   18 62240429 62240551 123 + 0.113 0.080 -0.565
ENSG00000134444 E021 7.9136251 0.0017491818 0.002914572 0.03380826 18 62244764 62244876 113 + 1.090 0.808 -1.058
ENSG00000134444 E022 6.1173003 0.0023983356 0.090676802 0.31274258 18 62252664 62252754 91 + 0.942 0.766 -0.681
ENSG00000134444 E023 0.6335114 0.0678277407 0.065128906 0.25702837 18 62254692 62254875 184 + 0.000 0.302 10.903
ENSG00000134444 E024 5.6892975 0.0035529259 0.669584446 0.86267659 18 62255407 62255478 72 + 0.783 0.835 0.205
ENSG00000134444 E025 7.4003856 0.0026696408 0.989917110 1.00000000 18 62257948 62258088 141 + 0.911 0.916 0.020
ENSG00000134444 E026 10.0045061 0.0016303414 0.740923918 0.89714860 18 62258512 62258676 165 + 1.010 1.044 0.124
ENSG00000134444 E027 8.1110416 0.0017617754 0.376762059 0.66394071 18 62261511 62261610 100 + 0.997 0.916 -0.302
ENSG00000134444 E028 5.6351871 0.0031193671 0.178823704 0.45381627 18 62261611 62261658 48 + 0.895 0.750 -0.565
ENSG00000134444 E029 13.2147986 0.0112129074 0.739175911 0.89660655 18 62263989 62264145 157 + 1.121 1.155 0.121
ENSG00000134444 E030 10.9557488 0.0012264582 0.613643166 0.83208081 18 62264729 62264852 124 + 1.090 1.052 -0.141
ENSG00000134444 E031 8.7875471 0.0017160729 0.553791370 0.79681759 18 62266701 62266749 49 + 0.942 1.002 0.226
ENSG00000134444 E032 0.0000000       18 62268515 62268868 354 +      
ENSG00000134444 E033 5.7017523 0.0031221394 0.466253905 0.73499982 18 62268869 62268880 12 + 0.761 0.847 0.342
ENSG00000134444 E034 8.1873589 0.0058537703 0.178792733 0.45378858 18 62268881 62268948 68 + 0.860 1.002 0.534
ENSG00000134444 E035 0.0000000       18 62269411 62269512 102 +      
ENSG00000134444 E036 6.6533878 0.0023251795 0.920844187 0.97524654 18 62273980 62274086 107 + 0.878 0.871 -0.025
ENSG00000134444 E037 9.9081564 0.0278057908 0.411222390 0.69291641 18 62275374 62275473 100 + 0.970 1.059 0.328
ENSG00000134444 E038 1.2264851 0.4513111273 0.623507688 0.83785787 18 62275474 62275707 234 + 0.397 0.302 -0.570
ENSG00000134444 E039 5.7479270 0.0500695045 0.029716605 0.16210053 18 62277178 62277595 418 + 0.599 0.916 1.283
ENSG00000134444 E040 2.3504205 0.0058882010 0.775545600 0.91380192 18 62277596 62277655 60 + 0.489 0.533 0.212
ENSG00000134444 E041 5.5254280 0.0027333413 0.372862656 0.66058874 18 62279774 62279856 83 + 0.860 0.766 -0.373
ENSG00000134444 E042 2.1319885 0.0130328006 0.051586524 0.22530366 18 62280326 62280359 34 + 0.277 0.582 1.657
ENSG00000134444 E043 7.6364919 0.0589196439 0.023021424 0.13842112 18 62280360 62280442 83 + 0.688 1.028 1.319
ENSG00000134444 E044 4.3839103 0.0159031342 0.015815985 0.10885903 18 62280443 62280645 203 + 0.489 0.822 1.435
ENSG00000134444 E045 9.4948753 0.0019169431 0.971327054 0.99450605 18 62280646 62280709 64 + 1.010 1.011 0.004
ENSG00000134444 E046 5.2998857 0.0708208128 0.968844088 0.99364123 18 62282306 62282315 10 + 0.783 0.794 0.047
ENSG00000134444 E047 4.3018972 0.0582321167 0.758189928 0.90510418 18 62282316 62282319 4 + 0.738 0.701 -0.150
ENSG00000134444 E048 14.6355645 0.0010293478 0.420491601 0.69979811 18 62282320 62282442 123 + 1.217 1.161 -0.200
ENSG00000134444 E049 6.0061173 0.0023520164 0.209380962 0.49365067 18 62282443 62282444 2 + 0.911 0.780 -0.506
ENSG00000134444 E050 0.9804258 0.0122009090 0.572060691 0.80817040 18 62284239 62284361 123 + 0.341 0.256 -0.565
ENSG00000134444 E051 4.4854602 0.0035952345 0.059518071 0.24466306 18 62285449 62285973 525 + 0.566 0.808 1.020
ENSG00000134444 E052 16.9323885 0.0008984793 0.495194346 0.75646666 18 62287351 62287467 117 + 1.209 1.263 0.188
ENSG00000134444 E053 12.8263857 0.0537711930 0.949330697 0.98676383 18 62291543 62291631 89 + 1.120 1.136 0.056
ENSG00000134444 E054 13.6704284 0.0011876277 0.765239133 0.90875604 18 62298790 62298860 71 + 1.167 1.149 -0.067
ENSG00000134444 E055 110.5728188 0.0010346378 0.217966498 0.50434618 18 62305414 62310249 4836 + 2.012 2.050 0.128

Help

Please Click HERE to learn more details about the results from DEXseq.