ENSG00000134480

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000256897 ENSG00000134480 No_inf pgKDN_inf CCNH protein_coding protein_coding 29.31383 33.54786 30.20359 1.332073 0.360674 -0.1514531 13.088116 0.8266419 18.462978 0.4775299 1.6268315 4.4646623 0.48700833 0.025975 0.611700 0.585725 1.215693e-06 1.215693e-06 FALSE TRUE
ENST00000505587 ENSG00000134480 No_inf pgKDN_inf CCNH protein_coding retained_intron 29.31383 33.54786 30.20359 1.332073 0.360674 -0.1514531 5.685372 12.3360606 2.941980 0.4120211 0.6240327 -2.0642958 0.18045833 0.369375 0.097875 -0.271500 5.578980e-04 1.215693e-06 TRUE FALSE
ENST00000508855 ENSG00000134480 No_inf pgKDN_inf CCNH protein_coding protein_coding 29.31383 33.54786 30.20359 1.332073 0.360674 -0.1514531 4.144075 8.6579529 2.498355 0.4220228 0.1420944 -1.7889496 0.13119167 0.258750 0.082800 -0.175950 5.161076e-03 1.215693e-06 FALSE TRUE
ENST00000510020 ENSG00000134480 No_inf pgKDN_inf CCNH protein_coding protein_coding_CDS_not_defined 29.31383 33.54786 30.20359 1.332073 0.360674 -0.1514531 1.865996 3.4500371 2.147952 2.4790309 2.1479521 -0.6811246 0.05672500 0.100650 0.069525 -0.031125 8.288365e-01 1.215693e-06 FALSE FALSE
ENST00000513499 ENSG00000134480 No_inf pgKDN_inf CCNH protein_coding protein_coding_CDS_not_defined 29.31383 33.54786 30.20359 1.332073 0.360674 -0.1514531 1.581354 3.6313185 1.112743 2.1349118 0.6805347 -1.6974331 0.04706667 0.103875 0.037325 -0.066550 9.519280e-01 1.215693e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134480 E001 0.9907492 0.0128250047 6.944048e-01 8.752268e-01 5 87318416 87318897 482 - 0.250 0.333 0.569
ENSG00000134480 E002 0.1272623 0.0123559053 6.708647e-01   5 87376253 87376255 3 - 0.000 0.090 9.908
ENSG00000134480 E003 0.3715287 0.1698913982 7.643396e-01   5 87376256 87376518 263 - 0.100 0.165 0.833
ENSG00000134480 E004 1.3766609 0.0092653505 6.773451e-02 2.626804e-01 5 87376519 87377180 662 - 0.181 0.488 2.002
ENSG00000134480 E005 41.0759093 0.0259287898 4.770636e-15 8.142389e-13 5 87391494 87392706 1213 - 1.137 1.814 2.336
ENSG00000134480 E006 6.7864409 0.0021330875 3.142984e-06 1.253799e-04 5 87392707 87392769 63 - 0.488 1.065 2.356
ENSG00000134480 E007 11.4091082 0.0112560769 5.134961e-07 2.543149e-05 5 87392770 87392904 135 - 0.712 1.263 2.061
ENSG00000134480 E008 47.0684892 0.0003312966 1.032720e-27 5.109974e-25 5 87393417 87394273 857 - 1.305 1.850 1.861
ENSG00000134480 E009 3.3332399 0.0686865916 4.957026e-01 7.567716e-01 5 87394274 87394279 6 - 0.555 0.693 0.599
ENSG00000134480 E010 5.7491711 0.0025762573 3.666285e-01 6.553022e-01 5 87394280 87394325 46 - 0.859 0.800 -0.229
ENSG00000134480 E011 7.1635579 0.0020343472 1.082880e-02 8.470492e-02 5 87394326 87394404 79 - 1.014 0.800 -0.814
ENSG00000134480 E012 8.4228646 0.0017295984 1.260410e-01 3.763960e-01 5 87394405 87394484 80 - 1.025 0.924 -0.377
ENSG00000134480 E013 2.6490356 0.0062686869 4.873918e-04 8.559749e-03 5 87394485 87395043 559 - 0.182 0.731 3.080
ENSG00000134480 E014 10.0627420 0.0017746975 8.630848e-04 1.338249e-02 5 87395044 87395104 61 - 1.161 0.912 -0.914
ENSG00000134480 E015 13.9682175 0.0113563532 1.680818e-03 2.232288e-02 5 87399394 87399505 112 - 1.282 1.057 -0.805
ENSG00000134480 E016 9.2162800 0.0018162633 1.050264e-03 1.555752e-02 5 87401702 87401772 71 - 1.129 0.873 -0.945
ENSG00000134480 E017 0.0000000       5 87401773 87401774 2 -      
ENSG00000134480 E018 0.3812526 0.0159490187 1.534573e-01   5 87404842 87404843 2 - 0.000 0.229 11.372
ENSG00000134480 E019 20.1567065 0.0007167094 6.455330e-06 2.331961e-04 5 87404844 87405007 164 - 1.439 1.198 -0.840
ENSG00000134480 E020 10.7533448 0.0013624166 3.978899e-06 1.544982e-04 5 87407976 87408006 31 - 1.226 0.873 -1.291
ENSG00000134480 E021 12.1432442 0.0022210135 8.333119e-11 8.448091e-09 5 87408007 87408037 31 - 1.322 0.816 -1.849
ENSG00000134480 E022 22.7962261 0.0005937444 3.128059e-14 4.976659e-12 5 87408038 87408186 149 - 1.553 1.137 -1.452
ENSG00000134480 E023 0.0000000       5 87409073 87409087 15 -      
ENSG00000134480 E024 0.1176306 0.0119620199 4.293508e-01   5 87409088 87409129 42 - 0.100 0.000 -11.044
ENSG00000134480 E025 0.3726934 0.0168262537 7.302146e-01   5 87409130 87409289 160 - 0.100 0.165 0.832
ENSG00000134480 E026 16.4752796 0.0009346727 1.371507e-06 6.123417e-05 5 87409290 87409363 74 - 1.377 1.082 -1.042
ENSG00000134480 E027 12.5106632 0.0025851218 3.412637e-04 6.462682e-03 5 87411224 87411346 123 - 1.246 1.000 -0.882
ENSG00000134480 E028 0.0000000       5 87412435 87412677 243 -      
ENSG00000134480 E029 0.0000000       5 87412678 87412930 253 -      

Help

Please Click HERE to learn more details about the results from DEXseq.