ENSG00000134504

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000408011 ENSG00000134504 No_inf pgKDN_inf KCTD1 protein_coding protein_coding 1.722979 1.238646 2.100008 0.2217346 0.4663919 0.756884 0.0842284 0.0000000 0.2526852 0.0000000 0.14766449 4.7152630 0.04856667 0.00000 0.145700 0.145700 0.69817296 0.01133326 FALSE TRUE
ENST00000578973 ENSG00000134504 No_inf pgKDN_inf KCTD1 protein_coding protein_coding 1.722979 1.238646 2.100008 0.2217346 0.4663919 0.756884 0.4188879 0.0000000 1.0764561 0.0000000 0.06291352 6.7634860 0.21218333 0.00000 0.582100 0.582100 0.01133326 0.01133326 FALSE TRUE
ENST00000580059 ENSG00000134504 No_inf pgKDN_inf KCTD1 protein_coding protein_coding 1.722979 1.238646 2.100008 0.2217346 0.4663919 0.756884 0.6957997 0.7331025 0.1685260 0.1201072 0.10580972 -2.0574269 0.52371667 0.67815 0.091950 -0.586200 0.17025616 0.01133326 FALSE TRUE
ENST00000580638 ENSG00000134504 No_inf pgKDN_inf KCTD1 protein_coding protein_coding 1.722979 1.238646 2.100008 0.2217346 0.4663919 0.756884 0.2213643 0.2237284 0.4403643 0.2237284 0.44036435 0.9462593 0.09712500 0.16485 0.126525 -0.038325 0.99926828 0.01133326 FALSE FALSE
ENST00000582494 ENSG00000134504 No_inf pgKDN_inf KCTD1 protein_coding protein_coding_CDS_not_defined 1.722979 1.238646 2.100008 0.2217346 0.4663919 0.756884 0.2451479 0.2818149 0.0000000 0.2818149 0.00000000 -4.8669819 0.09802500 0.15700 0.000000 -0.157000 0.80743401 0.01133326 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134504 E001 0.0000000       18 26454910 26454912 3 -      
ENSG00000134504 E002 0.0000000       18 26454913 26454973 61 -      
ENSG00000134504 E003 2.3403790 0.006960155 0.505587089 0.76442038 18 26454974 26455712 739 - 0.465 0.574 0.521
ENSG00000134504 E004 0.1268540 0.012949286 0.548502021   18 26455713 26455759 47 - 0.000 0.097 12.138
ENSG00000134504 E005 0.0000000       18 26455760 26455769 10 -      
ENSG00000134504 E006 0.6355564 0.030586362 0.021773748 0.13392214 18 26455770 26455891 122 - 0.000 0.352 14.015
ENSG00000134504 E007 0.1265070 0.013057658 0.548106305   18 26455892 26455901 10 - 0.000 0.097 12.138
ENSG00000134504 E008 0.2373413 0.017068451 0.229536642   18 26455902 26459619 3718 - 0.170 0.000 -13.295
ENSG00000134504 E009 0.9974544 0.012850465 0.152442144 0.41644094 18 26459620 26459788 169 - 0.170 0.398 1.647
ENSG00000134504 E010 1.1058639 0.014155833 0.768960667 0.91062684 18 26459789 26459925 137 - 0.292 0.352 0.384
ENSG00000134504 E011 0.0000000       18 26460806 26460876 71 -      
ENSG00000134504 E012 0.8613771 0.016847204 0.729609440 0.89222645 18 26476515 26476659 145 - 0.235 0.301 0.477
ENSG00000134504 E013 0.0000000       18 26476660 26476891 232 -      
ENSG00000134504 E014 1.1158743 0.011451390 0.322884833 0.61568569 18 26501072 26501250 179 - 0.235 0.398 1.062
ENSG00000134504 E015 9.1175187 0.001802958 0.006627161 0.06068409 18 26546728 26548553 1826 - 1.071 0.929 -0.523
ENSG00000134504 E016 0.2373413 0.017068451 0.229536642   18 26548891 26549435 545 - 0.170 0.000 -13.295
ENSG00000134504 E017 0.2539903 0.017516007 0.247219684   18 26549729 26549819 91 - 0.000 0.176 12.981
ENSG00000134504 E018 0.0000000       18 26581162 26581729 568 -      
ENSG00000134504 E019 0.0000000       18 26629147 26629237 91 -      
ENSG00000134504 E020 0.0000000       18 26629238 26629242 5 -      
ENSG00000134504 E021 0.0000000       18 26640311 26640344 34 -      
ENSG00000134504 E022 0.0000000       18 26657360 26657401 42 -      

Help

Please Click HERE to learn more details about the results from DEXseq.