ENSG00000134531

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000256951 ENSG00000134531 No_inf pgKDN_inf EMP1 protein_coding protein_coding 301.6047 174.9913 406.8118 1.630939 3.21508 1.217032 50.84548 36.782506 65.63120 1.414773 0.8382387 0.8351897 0.17554167 0.210000 0.161400 -0.048600 0.245961761 0.005919751 FALSE  
ENST00000396301 ENSG00000134531 No_inf pgKDN_inf EMP1 protein_coding protein_coding 301.6047 174.9913 406.8118 1.630939 3.21508 1.217032 17.98218 1.203859 25.29418 1.203859 1.9956262 4.3817030 0.05129167 0.007000 0.062200 0.055200 0.005919751 0.005919751 FALSE  
ENST00000431267 ENSG00000134531 No_inf pgKDN_inf EMP1 protein_coding protein_coding 301.6047 174.9913 406.8118 1.630939 3.21508 1.217032 40.59017 12.852851 61.58116 3.254716 2.7789172 2.2595129 0.12402500 0.073975 0.151325 0.077350 0.084420170 0.005919751 FALSE  
ENST00000542289 ENSG00000134531 No_inf pgKDN_inf EMP1 protein_coding protein_coding_CDS_not_defined 301.6047 174.9913 406.8118 1.630939 3.21508 1.217032 189.42210 121.178652 252.39903 3.969500 4.1384190 1.0585089 0.63835000 0.692000 0.620375 -0.071625 0.124750380 0.005919751    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134531 E001 2.0181834 4.373613e-02 7.974397e-03 6.901951e-02 12 13196723 13196725 3 + 0.585 0.126 -3.074
ENSG00000134531 E002 12.0189588 1.294311e-03 2.522549e-02 1.462059e-01 12 13196726 13196782 57 + 1.161 0.959 -0.737
ENSG00000134531 E003 11.5596043 1.238721e-03 1.257679e-01 3.759663e-01 12 13196783 13196785 3 + 1.128 0.990 -0.503
ENSG00000134531 E004 55.6538218 4.715819e-04 5.975413e-01 8.233137e-01 12 13196786 13196872 87 + 1.744 1.721 -0.079
ENSG00000134531 E005 0.9869128 1.177295e-02 1.102331e-01 3.483973e-01 12 13199178 13199533 356 + 0.185 0.429 1.663
ENSG00000134531 E006 1.2247547 1.006519e-02 3.186591e-01 6.112740e-01 12 13209100 13209570 471 + 0.276 0.429 0.926
ENSG00000134531 E007 54.7683467 2.703192e-04 3.727271e-01 6.605887e-01 12 13211469 13211510 42 + 1.743 1.704 -0.132
ENSG00000134531 E008 44.8340771 3.146341e-04 2.853742e-01 5.791020e-01 12 13211511 13211540 30 + 1.662 1.611 -0.174
ENSG00000134531 E009 65.7563050 2.379133e-04 3.048070e-01 5.980835e-01 12 13211541 13211588 48 + 1.822 1.781 -0.138
ENSG00000134531 E010 0.4801267 1.531001e-02 7.209831e-01   12 13211589 13211902 314 + 0.185 0.126 -0.659
ENSG00000134531 E011 0.7443107 1.403592e-02 1.117980e-01 3.511976e-01 12 13213415 13213451 37 + 0.132 0.371 1.926
ENSG00000134531 E012 0.4995438 1.531726e-02 1.025449e-01   12 13213452 13213478 27 + 0.071 0.304 2.511
ENSG00000134531 E013 125.8369677 1.403813e-03 1.663433e-01 4.365491e-01 12 13213479 13213575 97 + 2.102 2.057 -0.150
ENSG00000134531 E014 167.0428472 1.118782e-04 1.088810e-02 8.505677e-02 12 13213681 13213821 141 + 2.230 2.167 -0.212
ENSG00000134531 E015 0.6167962 2.367292e-01 3.002262e-01 5.930779e-01 12 13213822 13214533 712 + 0.132 0.304 1.512
ENSG00000134531 E016 62.1553573 2.388389e-04 5.143016e-01 7.710021e-01 12 13214534 13214570 37 + 1.793 1.766 -0.091
ENSG00000134531 E017 223.7766002 6.077295e-04 3.260059e-04 6.228411e-03 12 13214571 13215035 465 + 2.363 2.279 -0.282
ENSG00000134531 E018 2224.4551512 3.714564e-05 1.853911e-01 4.631244e-01 12 13215036 13216443 1408 + 3.332 3.326 -0.022
ENSG00000134531 E019 673.2734830 4.029609e-05 3.687072e-15 6.353309e-13 12 13216444 13219941 3498 + 2.778 2.865 0.288

Help

Please Click HERE to learn more details about the results from DEXseq.