ENSG00000134684

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373477 ENSG00000134684 No_inf pgKDN_inf YARS1 protein_coding protein_coding 51.29337 30.19176 58.33606 1.417242 1.419793 0.9500026 39.204697 18.854906 48.773732 0.3976908 0.8249197 1.37069524 0.743525 0.628250 0.83675 0.208500 0.0006914229 0.0006914229 FALSE TRUE
ENST00000478828 ENSG00000134684 No_inf pgKDN_inf YARS1 protein_coding retained_intron 51.29337 30.19176 58.33606 1.417242 1.419793 0.9500026 5.812744 4.922334 4.984986 1.8867252 0.9876442 0.01821008 0.118050 0.155025 0.08455 -0.070475 0.8756813166 0.0006914229 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134684 E001 0.9730273 0.0162050391 8.171217e-01 9.334824e-01 1 32775237 32775238 2 - 0.272 0.308 0.247
ENSG00000134684 E002 1.0818155 0.0155517124 4.632030e-01 7.332020e-01 1 32775239 32775243 5 - 0.346 0.228 -0.823
ENSG00000134684 E003 2.0369680 0.0142956620 1.537616e-01 4.186469e-01 1 32775244 32775260 17 - 0.536 0.308 -1.238
ENSG00000134684 E004 2.1556712 0.0108902287 1.144214e-01 3.563616e-01 1 32775261 32775272 12 - 0.558 0.308 -1.338
ENSG00000134684 E005 5.3015736 0.0036765830 3.725774e-01 6.604413e-01 1 32775273 32775282 10 - 0.817 0.710 -0.431
ENSG00000134684 E006 7.9558502 0.0021205956 2.732319e-01 5.670062e-01 1 32775283 32775308 26 - 0.971 0.857 -0.431
ENSG00000134684 E007 83.8576616 0.0001739278 2.614244e-01 5.541668e-01 1 32775309 32775680 372 - 1.895 1.933 0.126
ENSG00000134684 E008 94.1154583 0.0001920723 3.139514e-03 3.567774e-02 1 32775681 32775990 310 - 1.924 2.015 0.306
ENSG00000134684 E009 47.2036895 0.0002996866 9.160836e-01 9.737053e-01 1 32775991 32776091 101 - 1.662 1.667 0.018
ENSG00000134684 E010 58.0842210 0.0002902943 7.893624e-01 9.191620e-01 1 32779382 32779523 142 - 1.748 1.759 0.038
ENSG00000134684 E011 1.2228346 0.0182719841 2.947748e-01 5.880110e-01 1 32779524 32780084 561 - 0.272 0.435 0.984
ENSG00000134684 E012 72.2014648 0.0015239940 2.129727e-01 4.981555e-01 1 32780085 32780278 194 - 1.861 1.813 -0.163
ENSG00000134684 E013 0.9791975 0.0128657681 3.448184e-01 6.359402e-01 1 32780279 32780711 433 - 0.229 0.376 0.984
ENSG00000134684 E014 49.2276634 0.0003281351 9.363895e-01 9.818623e-01 1 32781048 32781145 98 - 1.683 1.680 -0.010
ENSG00000134684 E015 3.5837392 0.0451054411 6.418906e-03 5.928898e-02 1 32781146 32782103 958 - 0.464 0.857 1.695
ENSG00000134684 E016 61.7586436 0.0002608387 4.029926e-01 6.860456e-01 1 32782404 32782539 136 - 1.789 1.757 -0.110
ENSG00000134684 E017 7.1675960 0.0019717983 1.182522e-05 3.949111e-04 1 32782540 32783755 1216 - 0.684 1.127 1.695
ENSG00000134684 E018 1.8695682 0.0077176089 1.925144e-03 2.484583e-02 1 32786083 32786361 279 - 0.229 0.680 2.444
ENSG00000134684 E019 22.8260289 0.0007196759 5.880403e-01 8.171847e-01 1 32786362 32786369 8 - 1.370 1.336 -0.120
ENSG00000134684 E020 41.9334534 0.0003471779 5.173473e-01 7.728637e-01 1 32786370 32786447 78 - 1.624 1.593 -0.104
ENSG00000134684 E021 9.1645429 0.0015136943 5.324467e-08 3.308408e-06 1 32786448 32786939 492 - 0.742 1.244 1.869
ENSG00000134684 E022 45.4962098 0.0003569124 9.692434e-01 9.936412e-01 1 32786940 32787075 136 - 1.648 1.647 -0.004
ENSG00000134684 E023 1.1001338 0.0119753312 5.040730e-01 7.633482e-01 1 32787076 32787381 306 - 0.272 0.376 0.662
ENSG00000134684 E024 2.1066588 0.0650171898 1.987762e-02 1.264991e-01 1 32790653 32791161 509 - 0.311 0.680 1.858
ENSG00000134684 E025 34.1922450 0.0004797546 4.388312e-01 7.148607e-01 1 32791162 32791254 93 - 1.541 1.500 -0.140
ENSG00000134684 E026 0.8620399 0.0127429365 2.069707e-01 4.905967e-01 1 32797160 32797591 432 - 0.182 0.376 1.399
ENSG00000134684 E027 0.6011245 0.0174322371 5.257203e-01 7.783245e-01 1 32797592 32797638 47 - 0.229 0.128 -1.016
ENSG00000134684 E028 0.1186381 0.0117180474 1.000000e+00   1 32797639 32797762 124 - 0.070 0.000 -8.301
ENSG00000134684 E029 34.8168246 0.0004524166 2.095249e-02 1.306116e-01 1 32797763 32797843 81 - 1.575 1.450 -0.426
ENSG00000134684 E030 0.0000000       1 32797844 32798214 371 -      
ENSG00000134684 E031 0.2441403 0.0161562583 5.954806e-01   1 32804545 32804883 339 - 0.070 0.128 0.984
ENSG00000134684 E032 41.2053933 0.0077689622 4.094542e-01 6.917090e-01 1 32806482 32806611 130 - 1.622 1.574 -0.164
ENSG00000134684 E033 45.7398704 0.0003242514 9.130539e-01 9.724073e-01 1 32810591 32810730 140 - 1.648 1.654 0.019
ENSG00000134684 E034 23.2179442 0.0005726255 8.160541e-01 9.327765e-01 1 32810731 32810766 36 - 1.370 1.356 -0.050
ENSG00000134684 E035 46.2969410 0.0003074696 3.446901e-02 1.773181e-01 1 32810911 32811057 147 - 1.687 1.590 -0.332
ENSG00000134684 E036 0.3628435 0.0167619417 1.000000e+00   1 32811058 32811647 590 - 0.130 0.128 -0.016
ENSG00000134684 E037 25.8427528 0.0005386178 4.229654e-03 4.415838e-02 1 32817188 32818031 844 - 1.465 1.284 -0.628

Help

Please Click HERE to learn more details about the results from DEXseq.