ENSG00000134686

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373418 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding protein_coding 80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 14.437614 2.3249414 21.096307 2.3249414 1.3272103 3.1762159 0.22531667 0.025025 0.332325 0.307300 0.001500039 0.001500039 FALSE TRUE
ENST00000583214 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding miRNA 80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 29.829736 49.6873812 14.172523 35.1074244 14.1725232 -1.8090556 0.23427500 0.326300 0.124650 -0.201650 0.845658716 0.001500039   FALSE
MSTRG.662.2 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding   80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 4.347380 13.0421400 0.000000 4.6778726 0.0000000 -10.3500707 0.07602500 0.228075 0.000000 -0.228075 0.021645517 0.001500039 FALSE TRUE
MSTRG.662.3 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding   80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 4.189964 6.8538957 0.000000 4.0050838 0.0000000 -9.4228838 0.06099167 0.056700 0.000000 -0.056700 0.378444365 0.001500039 FALSE TRUE
MSTRG.662.4 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding   80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 5.084580 0.5878977 7.803540 0.5878977 0.1156089 3.7080057 0.06951667 0.006325 0.121675 0.115350 0.003608431 0.001500039 FALSE TRUE
MSTRG.662.5 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding   80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 12.405930 13.8957278 18.740203 2.6041088 3.9069078 0.4312270 0.18867500 0.228000 0.277025 0.049025 0.835809861 0.001500039 FALSE TRUE
MSTRG.662.9 ENSG00000134686 No_inf pgKDN_inf PHC2 protein_coding   80.02845 95.03656 70.81927 34.61958 14.37303 -0.4242886 6.637629 7.2581691 4.718648 1.7120209 2.6393573 -0.6201641 0.09844167 0.107525 0.080875 -0.026650 0.812500082 0.001500039 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134686 E001 0.0000000       1 33323623 33323625 3 -      
ENSG00000134686 E002 0.8506756 0.1807452213 9.534694e-01 0.9885479821 1 33323626 33323627 2 - 0.277 0.256 -0.149
ENSG00000134686 E003 8.0563461 0.0021593984 9.675702e-01 0.9934120530 1 33323628 33323681 54 - 0.956 0.957 0.002
ENSG00000134686 E004 290.5658536 0.0000980894 4.072259e-06 0.0001575561 1 33323682 33324688 1007 - 2.434 2.496 0.207
ENSG00000134686 E005 96.3436509 0.0001707808 9.916699e-03 0.0798246239 1 33324689 33325019 331 - 1.953 2.024 0.239
ENSG00000134686 E006 0.0000000       1 33325795 33325961 167 -      
ENSG00000134686 E007 3.2909988 0.0045962007 9.379204e-01 0.9821150715 1 33327348 33327427 80 - 0.638 0.625 -0.057
ENSG00000134686 E008 94.3703335 0.0090735815 7.117405e-01 0.8834797698 1 33328870 33329146 277 - 1.971 1.987 0.052
ENSG00000134686 E009 64.6686310 0.0029025365 2.664302e-01 0.5598709267 1 33330071 33330212 142 - 1.839 1.790 -0.167
ENSG00000134686 E010 21.1824855 0.0006321349 3.871408e-01 0.6730306431 1 33331348 33331363 16 - 1.372 1.314 -0.203
ENSG00000134686 E011 34.9962942 0.0004185888 6.546590e-01 0.8550694082 1 33331364 33331462 99 - 1.568 1.542 -0.089
ENSG00000134686 E012 0.3522653 0.0245247626 1.474815e-01   1 33331625 33331699 75 - 0.223 0.000 -12.991
ENSG00000134686 E013 0.1176306 0.0117232527 6.505482e-01   1 33331700 33331715 16 - 0.088 0.000 -11.570
ENSG00000134686 E014 36.1658710 0.0003951285 2.747322e-01 0.5681520146 1 33332275 33332392 118 - 1.596 1.538 -0.195
ENSG00000134686 E015 14.2991003 0.0084807788 5.822939e-02 0.2415988896 1 33332393 33332404 12 - 1.255 1.089 -0.590
ENSG00000134686 E016 0.8790649 0.1475100219 5.164554e-02 0.2254695196 1 33332405 33332492 88 - 0.088 0.417 2.849
ENSG00000134686 E017 1.2340718 0.0588125509 3.814217e-01 0.6678568571 1 33333844 33333932 89 - 0.277 0.417 0.850
ENSG00000134686 E018 21.8396733 0.0025768174 4.755666e-05 0.0012792623 1 33334090 33334184 95 - 1.468 1.190 -0.969
ENSG00000134686 E019 23.5522767 0.0009094393 3.393353e-02 0.1754005845 1 33334185 33334290 106 - 1.447 1.314 -0.464
ENSG00000134686 E020 8.5412188 0.0016076823 8.778253e-01 0.9585068685 1 33334291 33334292 2 - 0.987 0.969 -0.066
ENSG00000134686 E021 5.5443297 0.0039827754 9.644175e-02 0.3234958145 1 33335166 33335338 173 - 0.720 0.902 0.718
ENSG00000134686 E022 18.1720443 0.0009123162 8.221795e-01 0.9355154198 1 33349597 33349915 319 - 1.291 1.272 -0.066
ENSG00000134686 E023 0.4891593 0.0863676118 8.597633e-01   1 33353213 33353439 227 - 0.160 0.187 0.266
ENSG00000134686 E024 2.7421645 0.0051847432 1.033754e-03 0.0153635951 1 33354401 33354566 166 - 0.738 0.256 -2.472
ENSG00000134686 E025 0.8275094 0.0225715511 9.552327e-03 0.0780671602 1 33354838 33354840 3 - 0.409 0.000 -14.130
ENSG00000134686 E026 1.3075479 0.0093901763 9.412911e-03 0.0772718351 1 33354841 33354912 72 - 0.510 0.103 -3.057
ENSG00000134686 E027 4.4443083 0.0285876385 1.884716e-02 0.1220681929 1 33354913 33355253 341 - 0.860 0.533 -1.372
ENSG00000134686 E028 2.1776129 0.0082710811 3.129860e-01 0.6063377416 1 33367116 33367428 313 - 0.566 0.417 -0.735
ENSG00000134686 E029 0.3559794 0.0293055216 1.480251e-01   1 33368536 33368569 34 - 0.223 0.000 -12.960
ENSG00000134686 E030 0.8361061 0.0130385462 8.494605e-02 0.3012942564 1 33368570 33368622 53 - 0.369 0.103 -2.320
ENSG00000134686 E031 0.3641302 0.2014378609 7.503535e-01   1 33368623 33368688 66 - 0.160 0.103 -0.736
ENSG00000134686 E032 1.6593398 0.0081391096 1.773534e-03 0.0232734232 1 33370421 33370585 165 - 0.591 0.103 -3.435
ENSG00000134686 E033 1.5457666 0.0241797564 3.777609e-03 0.0408627255 1 33371017 33371094 78 - 0.566 0.103 -3.320
ENSG00000134686 E034 1.7958620 0.0144573573 4.530551e-02 0.2081529458 1 33372289 33372447 159 - 0.566 0.256 -1.735
ENSG00000134686 E035 3.1300626 0.0043971200 5.772454e-02 0.2403918705 1 33375366 33375593 228 - 0.720 0.459 -1.175
ENSG00000134686 E036 0.2448930 0.0163767884 8.809753e-01   1 33392682 33392765 84 - 0.088 0.103 0.265
ENSG00000134686 E037 1.9329681 0.0084464428 2.620366e-01 0.5547410306 1 33430181 33430646 466 - 0.539 0.370 -0.872
ENSG00000134686 E038 0.8268828 0.0125861014 8.971692e-03 0.0747792090 1 33430976 33431095 120 - 0.409 0.000 -14.200

Help

Please Click HERE to learn more details about the results from DEXseq.