ENSG00000134851

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381334 ENSG00000134851 No_inf pgKDN_inf TMEM165 protein_coding protein_coding 125.0115 80.22296 152.7247 3.122336 2.073902 0.9287614 101.225276 50.43175 134.711477 2.212066 2.968232 1.41729 0.783575 0.63355 0.882100 0.248550 5.393264e-06 5.393264e-06 FALSE TRUE
ENST00000509575 ENSG00000134851 No_inf pgKDN_inf TMEM165 protein_coding retained_intron 125.0115 80.22296 152.7247 3.122336 2.073902 0.9287614 7.234212 10.45821 3.489316 2.127261 1.384268 -1.58087 0.068475 0.12935 0.022525 -0.106825 7.256167e-02 5.393264e-06   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134851 E001 5.0969307 0.0120329119 6.112637e-01 8.308705e-01 4 55395957 55395962 6 + 0.745 0.810 0.260
ENSG00000134851 E002 76.8913205 0.0002590489 2.905367e-03 3.373478e-02 4 55395963 55396250 288 + 1.908 1.803 -0.354
ENSG00000134851 E003 66.1700431 0.0002257843 3.143036e-05 8.977558e-04 4 55396251 55396396 146 + 1.860 1.697 -0.549
ENSG00000134851 E004 0.2537079 0.2469867364 1.214695e-01   4 55397119 55397159 41 + 0.000 0.226 10.204
ENSG00000134851 E005 1.3794303 0.1890235914 1.347325e-02 9.756849e-02 4 55397160 55397271 112 + 0.131 0.610 3.131
ENSG00000134851 E006 0.3622142 0.0164234416 1.000000e+00   4 55397272 55397405 134 + 0.131 0.128 -0.040
ENSG00000134851 E007 0.8630139 0.0128205104 2.185344e-01 5.051535e-01 4 55398923 55399253 331 + 0.184 0.374 1.375
ENSG00000134851 E008 0.0000000       4 55403236 55403242 7 +      
ENSG00000134851 E009 0.3645386 0.2363976441 1.000000e+00   4 55403243 55403338 96 + 0.131 0.128 -0.040
ENSG00000134851 E010 109.0657025 0.0001614217 7.984396e-05 1.969947e-03 4 55411614 55411839 226 + 2.061 1.945 -0.390
ENSG00000134851 E011 3.0852845 0.0476355132 2.065132e-02 1.294620e-01 4 55411840 55412156 317 + 0.440 0.787 1.545
ENSG00000134851 E012 12.5008591 0.0010985238 8.432451e-10 7.300093e-08 4 55415271 55416157 887 + 0.864 1.365 1.813
ENSG00000134851 E013 3.1672651 0.0456865158 4.628041e-01 7.329899e-01 4 55416923 55417071 149 + 0.560 0.677 0.513
ENSG00000134851 E014 54.2986189 0.0008728507 8.340053e-02 2.975934e-01 4 55417072 55417128 57 + 1.749 1.676 -0.247
ENSG00000134851 E015 95.1334529 0.0001764209 2.608694e-01 5.534671e-01 4 55417129 55417247 119 + 1.976 1.943 -0.109
ENSG00000134851 E016 1.8596505 0.0073351865 1.126518e-02 8.700794e-02 4 55417691 55417802 112 + 0.274 0.645 1.960
ENSG00000134851 E017 88.7611546 0.0001880950 8.178467e-01 9.336977e-01 4 55417803 55417848 46 + 1.931 1.941 0.036
ENSG00000134851 E018 95.7962477 0.0002126142 8.122816e-01 9.309356e-01 4 55417849 55417918 70 + 1.963 1.974 0.036
ENSG00000134851 E019 73.7686990 0.0002064170 6.516566e-01 8.533477e-01 4 55417919 55417985 67 + 1.848 1.868 0.066
ENSG00000134851 E020 2.0957960 0.0880235690 8.687798e-02 3.055278e-01 4 55417986 55418047 62 + 0.348 0.645 1.475
ENSG00000134851 E021 4.1879162 0.0034561426 3.716407e-03 4.034636e-02 4 55418048 55418164 117 + 0.539 0.894 1.475
ENSG00000134851 E022 13.7700835 0.0237769313 5.802150e-08 3.576379e-06 4 55423114 55424537 1424 + 0.875 1.419 1.960
ENSG00000134851 E023 123.9328917 0.0001633708 3.427816e-01 6.341353e-01 4 55424538 55424643 106 + 2.067 2.097 0.098
ENSG00000134851 E024 3.9528367 0.0036330799 1.240292e-03 1.765912e-02 4 55424644 55424812 169 + 0.492 0.894 1.697
ENSG00000134851 E025 433.8295393 0.0001270546 1.978493e-01 4.792712e-01 4 55425376 55426175 800 + 2.612 2.632 0.066
ENSG00000134851 E026 9.2991261 0.0014777552 5.850263e-01 8.156131e-01 4 55452239 55453397 1159 + 1.013 0.963 -0.183

Help

Please Click HERE to learn more details about the results from DEXseq.