ENSG00000134905

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000257347 ENSG00000134905 No_inf pgKDN_inf CARS2 protein_coding protein_coding 40.37622 41.47622 36.86624 2.380816 0.8169964 -0.1699406 21.072935 17.138206 24.405122 0.8117965 0.5319852 0.5097173 0.53003333 0.420075 0.662100 0.242025 0.00778078 0.00778078 FALSE TRUE
ENST00000480437 ENSG00000134905 No_inf pgKDN_inf CARS2 protein_coding protein_coding_CDS_not_defined 40.37622 41.47622 36.86624 2.380816 0.8169964 -0.1699406 3.731560 6.983730 3.155626 0.5404617 0.2810947 -1.1435713 0.09482500 0.172200 0.086225 -0.085975 0.36906931 0.00778078 FALSE FALSE
ENST00000481787 ENSG00000134905 No_inf pgKDN_inf CARS2 protein_coding retained_intron 40.37622 41.47622 36.86624 2.380816 0.8169964 -0.1699406 3.533528 4.076904 0.000000 1.4024837 0.0000000 -8.6748644 0.08236667 0.092975 0.000000 -0.092975 0.02241018 0.00778078 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134905 E001 0.1176306 0.0117389259 4.921025e-01   13 110641412 110641416 5 - 0.098 0.000 -12.244
ENSG00000134905 E002 0.1176306 0.0117389259 4.921025e-01   13 110641417 110641418 2 - 0.098 0.000 -12.247
ENSG00000134905 E003 4.0531978 0.0084655500 7.966938e-01 0.923069467 13 110641419 110641442 24 - 0.682 0.720 0.162
ENSG00000134905 E004 24.4098489 0.0006406343 9.976855e-01 1.000000000 13 110641443 110641583 141 - 1.399 1.408 0.029
ENSG00000134905 E005 11.0843847 0.0012916269 7.383471e-02 0.276772414 13 110641584 110641586 3 - 1.152 1.009 -0.517
ENSG00000134905 E006 13.9097666 0.0011102911 1.572936e-01 0.423854154 13 110641587 110641608 22 - 1.223 1.123 -0.355
ENSG00000134905 E007 22.2370772 0.0006305552 1.747418e-01 0.448551939 13 110642315 110642386 72 - 1.404 1.329 -0.260
ENSG00000134905 E008 19.8842605 0.0074696666 8.504062e-01 0.946982055 13 110642387 110642446 60 - 1.307 1.329 0.077
ENSG00000134905 E009 17.0952434 0.0009448572 4.558117e-01 0.728213185 13 110642447 110642497 51 - 1.223 1.283 0.211
ENSG00000134905 E010 10.0510022 0.0015684137 8.547582e-01 0.948765721 13 110642498 110642510 13 - 1.047 1.038 -0.031
ENSG00000134905 E011 11.4092499 0.0013059706 9.309216e-01 0.979859554 13 110642511 110642521 11 - 1.085 1.100 0.054
ENSG00000134905 E012 8.8351344 0.0015597869 7.991838e-04 0.012595902 13 110642522 110643752 1231 - 0.783 1.116 1.249
ENSG00000134905 E013 2.0120918 0.0411340357 4.819101e-03 0.048238505 13 110643753 110643955 203 - 0.178 0.634 2.706
ENSG00000134905 E014 0.7611853 0.1364177275 2.332347e-02 0.139491088 13 110643956 110643980 25 - 0.000 0.383 14.523
ENSG00000134905 E015 0.8711996 0.0128460135 3.057764e-01 0.599002798 13 110643981 110644064 84 - 0.178 0.339 1.220
ENSG00000134905 E016 4.2223141 0.1520188680 2.564148e-01 0.548505732 13 110644065 110644182 118 - 0.579 0.809 0.961
ENSG00000134905 E017 1.4882782 0.0111089477 3.186147e-01 0.611261732 13 110644183 110644384 202 - 0.304 0.461 0.898
ENSG00000134905 E018 10.6356931 0.0013628014 4.613009e-01 0.732081874 13 110644385 110644386 2 - 1.094 1.038 -0.201
ENSG00000134905 E019 26.3766190 0.0069073640 9.307199e-01 0.979806458 13 110644387 110644483 97 - 1.429 1.443 0.046
ENSG00000134905 E020 1.8574216 0.0949175771 3.630272e-01 0.652128678 13 110644484 110644606 123 - 0.356 0.527 0.898
ENSG00000134905 E021 5.7126056 0.0024831602 1.775079e-02 0.117247480 13 110644607 110645633 1027 - 0.658 0.933 1.091
ENSG00000134905 E022 0.9809639 0.0220400188 8.990716e-01 0.966948335 13 110645930 110645966 37 - 0.304 0.289 -0.102
ENSG00000134905 E023 26.9648052 0.0005686806 1.466584e-01 0.407683374 13 110645967 110646090 124 - 1.395 1.485 0.310
ENSG00000134905 E024 15.4209235 0.0010741311 2.185612e-05 0.000664106 13 110646091 110646466 376 - 1.005 1.338 1.188
ENSG00000134905 E025 1.8497699 0.0483895702 5.841488e-01 0.815115778 13 110646467 110646504 38 - 0.402 0.495 0.483
ENSG00000134905 E026 4.6172420 0.1295512658 3.538918e-02 0.180056343 13 110646505 110646631 127 - 0.516 0.882 1.535
ENSG00000134905 E027 2.6315943 0.0107506161 7.338696e-03 0.065180477 13 110646632 110646678 47 - 0.304 0.700 1.986
ENSG00000134905 E028 3.1134165 0.0761175907 9.721569e-02 0.324752165 13 110646679 110646850 172 - 0.443 0.720 1.260
ENSG00000134905 E029 0.6340457 0.1581416479 4.339165e-02 0.203197874 13 110646851 110646860 10 - 0.000 0.339 14.260
ENSG00000134905 E030 2.1064912 0.0996024883 3.971402e-01 0.681455831 13 110646861 110647100 240 - 0.402 0.556 0.772
ENSG00000134905 E031 24.3412345 0.0009646604 4.280389e-01 0.706551153 13 110647101 110647239 139 - 1.372 1.427 0.191
ENSG00000134905 E032 1.9955719 0.0091102175 6.518932e-02 0.257058924 13 110648318 110649297 980 - 0.304 0.584 1.483
ENSG00000134905 E033 0.4999558 0.0153490954 3.639573e-01 0.652655289 13 110650247 110650636 390 - 0.098 0.233 1.483
ENSG00000134905 E034 0.7453218 0.0282132446 4.840740e-01 0.748350273 13 110650637 110651033 397 - 0.178 0.289 0.898
ENSG00000134905 E035 17.6792980 0.0007941095 8.972632e-01 0.966130814 13 110651034 110651100 67 - 1.261 1.278 0.059
ENSG00000134905 E036 0.2444846 0.0163862937 9.445194e-01   13 110651101 110651207 107 - 0.098 0.092 -0.102
ENSG00000134905 E037 0.4992916 0.0384402460 3.685775e-01   13 110662838 110663050 213 - 0.098 0.233 1.484
ENSG00000134905 E038 21.2063895 0.0006650676 7.154454e-01 0.885325876 13 110663451 110663518 68 - 1.353 1.338 -0.052
ENSG00000134905 E039 5.8133441 0.0024299463 1.118714e-01 0.351301414 13 110663519 110663861 343 - 0.725 0.908 0.718
ENSG00000134905 E040 2.7169365 0.0458153437 3.449601e-01 0.635984048 13 110663975 110664046 72 - 0.481 0.634 0.706
ENSG00000134905 E041 1.7355980 0.0856847766 4.317229e-01 0.709334270 13 110665528 110665791 264 - 0.356 0.495 0.746
ENSG00000134905 E042 22.8228849 0.0007155971 6.159306e-02 0.249396413 13 110667340 110667435 96 - 1.429 1.324 -0.365
ENSG00000134905 E043 10.1470063 0.0013589200 4.621779e-01 0.732676034 13 110667436 110667473 38 - 1.076 1.019 -0.206
ENSG00000134905 E044 8.2042191 0.0017396608 8.066585e-01 0.928630049 13 110676974 110676998 25 - 0.972 0.956 -0.059
ENSG00000134905 E045 16.4373214 0.0009849759 8.647988e-01 0.953233621 13 110676999 110677095 97 - 1.230 1.250 0.071
ENSG00000134905 E046 8.5774710 0.0016783699 8.918414e-01 0.964091974 13 110677096 110677103 8 - 0.983 0.978 -0.019
ENSG00000134905 E047 0.0000000       13 110677923 110678093 171 -      
ENSG00000134905 E048 16.1694973 0.0008907263 7.327314e-01 0.893744290 13 110683051 110683134 84 - 1.243 1.226 -0.058
ENSG00000134905 E049 0.0000000       13 110683135 110683139 5 -      
ENSG00000134905 E050 6.8668744 0.0023464136 9.465560e-01 0.985717713 13 110687721 110687721 1 - 0.895 0.895 0.001
ENSG00000134905 E051 8.7097495 0.0016189735 9.820499e-01 0.998476555 13 110687722 110687731 10 - 0.983 0.989 0.020
ENSG00000134905 E052 12.7114507 0.0010936514 2.959437e-01 0.589010876 13 110687732 110687791 60 - 1.174 1.100 -0.268
ENSG00000134905 E053 11.4264438 0.0013628662 2.222730e-02 0.135576431 13 110687792 110687826 35 - 1.182 0.999 -0.661
ENSG00000134905 E054 17.2296480 0.0026117903 9.282049e-04 0.014175692 13 110687947 110688018 72 - 1.368 1.139 -0.806
ENSG00000134905 E055 0.0000000       13 110688785 110688904 120 -      
ENSG00000134905 E056 0.6053466 0.2119479306 6.166035e-01 0.833854399 13 110697918 110697967 50 - 0.245 0.168 -0.685
ENSG00000134905 E057 0.0000000       13 110701351 110701437 87 -      
ENSG00000134905 E058 18.8966310 0.0008456919 3.653933e-02 0.183855579 13 110701438 110701501 64 - 1.363 1.232 -0.457
ENSG00000134905 E059 14.3411902 0.0018790280 6.982072e-01 0.876859087 13 110701502 110701555 54 - 1.196 1.174 -0.077
ENSG00000134905 E060 15.7253225 0.0014371132 4.590135e-02 0.209894058 13 110705521 110705571 51 - 1.290 1.153 -0.484
ENSG00000134905 E061 0.7275121 0.0898642053 3.938411e-01 0.678673217 13 110705572 110705797 226 - 0.304 0.168 -1.102
ENSG00000134905 E062 18.5616549 0.0011098875 3.830774e-04 0.007058729 13 110705870 110706133 264 - 1.399 1.167 -0.813
ENSG00000134905 E063 0.0000000       13 110706371 110706505 135 -      
ENSG00000134905 E064 0.0000000       13 110707338 110707643 306 -      
ENSG00000134905 E065 0.3716209 0.0166698084 6.405962e-01   13 110712232 110712486 255 - 0.098 0.168 0.898
ENSG00000134905 E066 1.2677812 0.1918098002 5.690114e-03 0.054316926 13 110713137 110713302 166 - 0.000 0.527 15.260
ENSG00000134905 E067 1.0141379 0.4427053372 5.405506e-02 0.231418130 13 110713303 110713603 301 - 0.000 0.461 14.937

Help

Please Click HERE to learn more details about the results from DEXseq.