ENSG00000134954

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319397 ENSG00000134954 No_inf pgKDN_inf ETS1 protein_coding protein_coding 78.57537 119.1129 76.89374 1.103301 0.6579807 -0.6313256 46.17281 61.17493 52.51532 2.405399 1.425254 -0.2201632 0.6074667 0.513750 0.68345 0.169700 0.009785633 0.006941539 FALSE TRUE
ENST00000535549 ENSG00000134954 No_inf pgKDN_inf ETS1 protein_coding protein_coding 78.57537 119.1129 76.89374 1.103301 0.6579807 -0.6313256 30.14245 54.90580 21.82821 2.063280 1.800853 -1.3303667 0.3631333 0.461075 0.28345 -0.177625 0.006941539 0.006941539 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134954 E001 0.0000000       11 128458761 128458764 4 -      
ENSG00000134954 E002 979.1207129 8.061193e-05 3.145570e-16 6.016070e-14 11 128458765 128460243 1479 - 2.926 2.997 0.236
ENSG00000134954 E003 814.8775949 4.278991e-05 8.888420e-03 7.431220e-02 11 128460244 128461493 1250 - 2.877 2.902 0.084
ENSG00000134954 E004 365.5109988 1.482720e-04 1.932987e-05 5.998489e-04 11 128461494 128462543 1050 - 2.588 2.520 -0.225
ENSG00000134954 E005 48.9276240 3.278189e-04 8.337690e-01 9.401262e-01 11 128462544 128462576 33 - 1.686 1.677 -0.031
ENSG00000134954 E006 66.1997147 2.226446e-04 4.819915e-03 4.823851e-02 11 128463509 128463627 119 - 1.874 1.768 -0.356
ENSG00000134954 E007 0.8544546 4.483559e-01 3.720531e-01 6.599457e-01 11 128463628 128463950 323 - 0.356 0.195 -1.160
ENSG00000134954 E008 104.7721558 1.247433e-03 2.488744e-03 3.000177e-02 11 128480191 128480400 210 - 2.067 1.968 -0.332
ENSG00000134954 E009 49.5176591 2.386889e-03 6.468134e-02 2.563749e-01 11 128480401 128480451 51 - 1.739 1.652 -0.296
ENSG00000134954 E010 94.7197785 9.645724e-04 2.874074e-04 5.608188e-03 11 128484823 128485071 249 - 2.036 1.915 -0.406
ENSG00000134954 E011 46.3752112 1.874910e-03 6.744092e-05 1.702883e-03 11 128486069 128486146 78 - 1.768 1.580 -0.638
ENSG00000134954 E012 76.1856920 2.891753e-04 5.759761e-05 1.496373e-03 11 128489290 128489469 180 - 1.954 1.814 -0.474
ENSG00000134954 E013 21.2642498 6.839299e-04 5.720332e-02 2.390164e-01 11 128489470 128489490 21 - 1.405 1.282 -0.427
ENSG00000134954 E014 43.3322850 3.256083e-04 5.957618e-01 8.222680e-01 11 128490457 128490576 120 - 1.644 1.620 -0.084
ENSG00000134954 E015 0.7630396 1.487481e-01 6.803704e-02 2.632099e-01 11 128504991 128505394 404 - 0.000 0.329 10.002
ENSG00000134954 E016 73.1631631 3.643490e-04 2.620002e-01 5.547133e-01 11 128521913 128522310 398 - 1.878 1.837 -0.138
ENSG00000134954 E017 0.0000000       11 128536412 128536783 372 -      
ENSG00000134954 E018 0.2435110 1.613357e-02 6.879910e-01   11 128556291 128556435 145 - 0.120 0.075 -0.745
ENSG00000134954 E019 0.0000000       11 128571808 128572314 507 -      
ENSG00000134954 E020 0.2441403 1.614618e-02 6.879848e-01   11 128573062 128573144 83 - 0.120 0.075 -0.745
ENSG00000134954 E021 0.0000000       11 128587486 128587487 2 -      
ENSG00000134954 E022 0.0000000       11 128587488 128587558 71 -      

Help

Please Click HERE to learn more details about the results from DEXseq.