ENSG00000134955

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354617 ENSG00000134955 No_inf pgKDN_inf SLC37A2 protein_coding protein_coding_CDS_not_defined 114.8516 76.34282 139.6498 1.118753 0.4381799 0.8711631 37.367519 34.470260 42.176679 1.6995438 1.9820697 0.2910169 0.3425000 0.450825 0.301900 -0.148925 1.540286e-02 1.332229e-06 FALSE TRUE
ENST00000403796 ENSG00000134955 No_inf pgKDN_inf SLC37A2 protein_coding protein_coding 114.8516 76.34282 139.6498 1.118753 0.4381799 0.8711631 71.065559 33.994499 92.581173 0.7027799 1.2813798 1.4451490 0.5945917 0.445950 0.663025 0.217075 1.332229e-06 1.332229e-06 FALSE TRUE
ENST00000526405 ENSG00000134955 No_inf pgKDN_inf SLC37A2 protein_coding retained_intron 114.8516 76.34282 139.6498 1.118753 0.4381799 0.8711631 5.254608 6.647674 3.389926 0.8459730 0.1584652 -0.9695149 0.0520500 0.087275 0.024250 -0.063025 1.270732e-02 1.332229e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000134955 E001 7.397156 0.0078988441 8.693185e-01 9.550776e-01 11 125063302 125063304 3 + 0.907 0.925 0.069
ENSG00000134955 E002 17.608199 0.0147089372 2.398250e-01 5.288976e-01 11 125063305 125063334 30 + 1.296 1.190 -0.372
ENSG00000134955 E003 15.446163 0.0335536547 5.073746e-01 7.658115e-01 11 125063335 125063335 1 + 1.235 1.153 -0.291
ENSG00000134955 E004 19.400774 0.0282961214 2.349190e-01 5.240785e-01 11 125063336 125063351 16 + 1.342 1.217 -0.441
ENSG00000134955 E005 33.495007 0.0166897307 5.708002e-02 2.388192e-01 11 125063352 125063426 75 + 1.577 1.428 -0.513
ENSG00000134955 E006 37.456525 0.0145017942 2.137726e-01 4.990741e-01 11 125076757 125076838 82 + 1.605 1.517 -0.298
ENSG00000134955 E007 39.195365 0.0148594854 6.780153e-02 2.627734e-01 11 125077230 125077323 94 + 1.637 1.509 -0.439
ENSG00000134955 E008 32.734760 0.0066767279 1.825037e-01 4.588668e-01 11 125077450 125077528 79 + 1.547 1.463 -0.287
ENSG00000134955 E009 45.618107 0.0260762748 4.444663e-01 7.190548e-01 11 125079112 125079247 136 + 1.677 1.622 -0.184
ENSG00000134955 E010 32.445499 0.0005079633 1.774216e-02 1.172104e-01 11 125079684 125079760 77 + 1.558 1.428 -0.447
ENSG00000134955 E011 71.094070 0.0046685627 5.324523e-03 5.184561e-02 11 125080614 125080780 167 + 1.891 1.761 -0.438
ENSG00000134955 E012 31.519681 0.0005395494 8.689658e-01 9.548879e-01 11 125081421 125081458 38 + 1.503 1.495 -0.027
ENSG00000134955 E013 70.117476 0.0042155584 9.618267e-01 9.916848e-01 11 125081754 125081906 153 + 1.840 1.839 -0.005
ENSG00000134955 E014 64.895254 0.0112971973 8.555511e-01 9.491670e-01 11 125082244 125082334 91 + 1.810 1.801 -0.033
ENSG00000134955 E015 1.596345 0.0085801867 2.140274e-01 4.991821e-01 11 125083139 125083424 286 + 0.325 0.513 1.016
ENSG00000134955 E016 45.651447 0.0003167177 4.426688e-01 7.179341e-01 11 125083815 125083847 33 + 1.670 1.636 -0.116
ENSG00000134955 E017 46.944572 0.0003045732 2.360912e-01 5.253895e-01 11 125083848 125083877 30 + 1.688 1.636 -0.179
ENSG00000134955 E018 73.384796 0.0002481721 1.238271e-03 1.764463e-02 11 125084234 125084319 86 + 1.901 1.783 -0.400
ENSG00000134955 E019 56.601679 0.0002627148 9.035981e-02 3.121636e-01 11 125084825 125084873 49 + 1.774 1.704 -0.235
ENSG00000134955 E020 71.667641 0.0002294348 2.655548e-01 5.588760e-01 11 125085066 125085139 74 + 1.864 1.824 -0.134
ENSG00000134955 E021 61.867124 0.0003360929 2.297136e-02 1.382434e-01 11 125085395 125085473 79 + 1.819 1.729 -0.305
ENSG00000134955 E022 70.592452 0.0002196080 2.364801e-01 5.254744e-01 11 125085577 125085674 98 + 1.859 1.816 -0.144
ENSG00000134955 E023 62.600334 0.0002341787 2.916694e-01 5.851242e-01 11 125085954 125086018 65 + 1.806 1.766 -0.136
ENSG00000134955 E024 7.159189 0.0018835910 3.027998e-04 5.851381e-03 11 125086019 125086203 185 + 0.722 1.089 1.399
ENSG00000134955 E025 3.684242 0.0076118306 7.062714e-02 2.691637e-01 11 125086204 125086260 57 + 0.557 0.789 0.986
ENSG00000134955 E026 59.783226 0.0038230240 1.956518e-30 1.172476e-27 11 125086261 125088118 1858 + 1.483 2.023 1.829
ENSG00000134955 E027 1133.573044 0.0001920250 1.014691e-04 2.402385e-03 11 125088119 125090516 2398 + 3.031 3.060 0.096

Help

Please Click HERE to learn more details about the results from DEXseq.