ENSG00000135048

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000377044 ENSG00000135048 No_inf pgKDN_inf CEMIP2 protein_coding protein_coding 26.84721 42.18835 20.85511 0.6341646 1.764421 -1.016094 9.101393 10.809483 9.7484294 0.7181899 0.4234796 -0.1489108 0.37411667 0.256375 0.47440 0.218025 0.04611465 0.04611465 FALSE TRUE
ENST00000377055 ENSG00000135048 No_inf pgKDN_inf CEMIP2 protein_coding protein_coding 26.84721 42.18835 20.85511 0.6341646 1.764421 -1.016094 2.345583 4.149866 0.4531646 1.8009685 0.4531646 -3.1669402 0.08153333 0.099400 0.01935 -0.080050 0.49018239 0.04611465 FALSE TRUE
ENST00000377057 ENSG00000135048 No_inf pgKDN_inf CEMIP2 protein_coding retained_intron 26.84721 42.18835 20.85511 0.6341646 1.764421 -1.016094 12.831356 21.355344 8.8801245 1.0439304 1.2051458 -1.2649970 0.46916667 0.507350 0.42160 -0.085750 0.73023587 0.04611465 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135048 E001 0.3700180 0.2529555270 1.0000000000   9 71683366 71683371 6 - 0.119 0.139 0.258
ENSG00000135048 E002 6.3778392 0.0035496284 0.0166931722 0.112667945 9 71683372 71683570 199 - 0.652 0.933 1.120
ENSG00000135048 E003 64.8430134 0.0013455967 0.0689948219 0.265418454 9 71683571 71683984 414 - 1.751 1.825 0.249
ENSG00000135048 E004 192.6469303 0.0001146800 0.0023048882 0.028375220 9 71683985 71685055 1071 - 2.228 2.290 0.205
ENSG00000135048 E005 57.0742985 0.0004598241 0.8267295925 0.937232700 9 71685056 71685393 338 - 1.751 1.743 -0.029
ENSG00000135048 E006 19.1590698 0.0008256319 0.9932580261 1.000000000 9 71685743 71685846 104 - 1.287 1.287 0.000
ENSG00000135048 E007 1.8801090 0.0503943698 0.1758772972 0.449993198 9 71685847 71687428 1582 - 0.290 0.515 1.257
ENSG00000135048 E008 21.5764552 0.0009956504 0.2049857589 0.488138219 9 71690092 71690246 155 - 1.280 1.364 0.295
ENSG00000135048 E009 16.7177714 0.0252954583 0.0110058642 0.085593407 9 71694509 71694607 99 - 1.047 1.307 0.930
ENSG00000135048 E010 0.1268540 0.0123251736 1.0000000000   9 71697828 71697984 157 - 0.000 0.075 10.219
ENSG00000135048 E011 36.1687994 0.0003964386 0.3136884912 0.606810196 9 71697985 71698204 220 - 1.518 1.570 0.177
ENSG00000135048 E012 0.5075387 0.0461221453 0.1406652197 0.398960768 9 71698205 71698241 37 - 0.000 0.245 11.976
ENSG00000135048 E013 1.1337489 0.0567694306 0.0944751252 0.319864180 9 71699192 71699449 258 - 0.119 0.400 2.258
ENSG00000135048 E014 28.0042352 0.0138384604 0.4041655086 0.686992201 9 71700642 71700824 183 - 1.484 1.421 -0.216
ENSG00000135048 E015 0.0000000       9 71704417 71704594 178 -      
ENSG00000135048 E016 26.9647602 0.0005868166 0.7232226281 0.888809398 9 71704595 71704799 205 - 1.415 1.436 0.073
ENSG00000135048 E017 6.0670432 0.0023507420 0.6976515101 0.876578603 9 71704800 71704803 4 - 0.805 0.849 0.170
ENSG00000135048 E018 0.0000000       9 71704804 71704932 129 -      
ENSG00000135048 E019 27.3850447 0.0005507352 0.2244061611 0.511911428 9 71709259 71709474 216 - 1.388 1.460 0.248
ENSG00000135048 E020 19.5054473 0.0014419360 0.7540841491 0.903253037 9 71712083 71712260 178 - 1.308 1.287 -0.073
ENSG00000135048 E021 0.3809057 0.0159180603 0.2476785549   9 71712261 71712443 183 - 0.000 0.195 11.730
ENSG00000135048 E022 14.8154361 0.0012921779 0.8320951180 0.939346494 9 71714934 71715089 156 - 1.192 1.176 -0.056
ENSG00000135048 E023 6.9519385 0.0024538464 0.2742605140 0.567786218 9 71716517 71716552 36 - 0.805 0.923 0.456
ENSG00000135048 E024 14.2939578 0.0010551833 0.3784474089 0.665422917 9 71717948 71718079 132 - 1.209 1.142 -0.240
ENSG00000135048 E025 11.3392262 0.0029125390 0.3352092808 0.627074238 9 71722427 71722515 89 - 1.125 1.043 -0.300
ENSG00000135048 E026 12.5783698 0.0015414493 0.4346116046 0.711817930 9 71725581 71725709 129 - 1.155 1.092 -0.228
ENSG00000135048 E027 9.9863054 0.0120793981 0.5580664108 0.799764931 9 71729845 71729914 70 - 1.059 1.004 -0.202
ENSG00000135048 E028 12.5226795 0.0168122390 0.1250022167 0.374902383 9 71730048 71730152 105 - 1.201 1.057 -0.515
ENSG00000135048 E029 10.6032333 0.0027491223 0.0004518712 0.008077965 9 71730153 71730253 101 - 1.218 0.913 -1.109
ENSG00000135048 E030 6.8460063 0.0061632908 0.0340512780 0.175827825 9 71730705 71730738 34 - 1.008 0.786 -0.845
ENSG00000135048 E031 15.0498861 0.0154271674 0.0131042536 0.095866316 9 71730739 71730914 176 - 1.314 1.098 -0.766
ENSG00000135048 E032 0.2545247 0.2448088161 0.5403393252   9 71730915 71730984 70 - 0.000 0.139 10.528
ENSG00000135048 E033 15.0481111 0.0010064185 0.0018949512 0.024561955 9 71732351 71732520 170 - 1.321 1.092 -0.813
ENSG00000135048 E034 11.4851857 0.0021675721 0.7984516524 0.924192880 9 71734806 71734994 189 - 1.093 1.071 -0.079
ENSG00000135048 E035 8.1656721 0.0511241294 0.8345446245 0.940355913 9 71740063 71740232 170 - 0.934 0.952 0.065
ENSG00000135048 E036 24.6094426 0.0014653255 0.0601806437 0.246226409 9 71745018 71745579 562 - 1.460 1.346 -0.394
ENSG00000135048 E037 5.0148905 0.0043637230 0.0771054153 0.284054993 9 71746201 71746341 141 - 0.884 0.680 -0.813
ENSG00000135048 E038 0.1271363 0.0124355434 1.0000000000   9 71750001 71750042 42 - 0.000 0.075 10.219
ENSG00000135048 E039 11.2308888 0.0012562922 0.0010379355 0.015417243 9 71750043 71750318 276 - 1.226 0.952 -0.994
ENSG00000135048 E040 3.0591082 0.0514498477 0.1802615217 0.455715052 9 71750319 71750385 67 - 0.709 0.515 -0.858
ENSG00000135048 E041 4.7830014 0.0030793291 0.1542235496 0.419523525 9 71768357 71768513 157 - 0.846 0.680 -0.668
ENSG00000135048 E042 0.0000000       9 71814955 71815292 338 -      
ENSG00000135048 E043 0.0000000       9 71816563 71816690 128 -      

Help

Please Click HERE to learn more details about the results from DEXseq.