ENSG00000135049

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337006 ENSG00000135049 No_inf pgKDN_inf AGTPBP1 protein_coding protein_coding 7.004403 6.647186 7.76566 0.2759445 0.2513823 0.2240527 1.1825071 1.4027405 0.0000000 0.8208257 0.0000000 -7.1423527 0.17400833 0.197600 0.000000 -0.197600 0.46582042 0.04405302 FALSE TRUE
ENST00000357081 ENSG00000135049 No_inf pgKDN_inf AGTPBP1 protein_coding protein_coding 7.004403 6.647186 7.76566 0.2759445 0.2513823 0.2240527 2.4037379 0.6810599 5.3645123 0.6810599 0.8840404 2.9592511 0.32646667 0.106275 0.695100 0.588825 0.04405302 0.04405302 FALSE TRUE
ENST00000376083 ENSG00000135049 No_inf pgKDN_inf AGTPBP1 protein_coding protein_coding 7.004403 6.647186 7.76566 0.2759445 0.2513823 0.2240527 1.6197930 1.6416395 1.8566232 0.9618645 1.1395496 0.1765319 0.23209167 0.263450 0.232775 -0.030675 1.00000000 0.04405302 FALSE TRUE
ENST00000628899 ENSG00000135049 No_inf pgKDN_inf AGTPBP1 protein_coding protein_coding 7.004403 6.647186 7.76566 0.2759445 0.2513823 0.2240527 0.3614643 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.05809167 0.000000 0.000000 0.000000   0.04405302 FALSE TRUE
MSTRG.28899.4 ENSG00000135049 No_inf pgKDN_inf AGTPBP1 protein_coding   7.004403 6.647186 7.76566 0.2759445 0.2513823 0.2240527 1.3884878 2.7765055 0.5445243 0.9616295 0.5445243 -2.3291343 0.20270000 0.412750 0.072125 -0.340625 0.26426101 0.04405302 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135049 E001 0.0000000       9 85546539 85546539 1 -      
ENSG00000135049 E002 0.4804091 0.015344794 0.362527970   9 85546540 85546559 20 - 0.231 0.099 -1.461
ENSG00000135049 E003 2.5484496 0.006534775 0.374467659 0.66209817 9 85546560 85546670 111 - 0.607 0.483 -0.579
ENSG00000135049 E004 31.8847403 0.002657941 0.191842574 0.47159696 9 85546671 85547286 616 - 1.482 1.550 0.233
ENSG00000135049 E005 0.2448930 0.016348085 0.946453745   9 85553873 85554272 400 - 0.092 0.099 0.122
ENSG00000135049 E006 11.6090441 0.001278121 0.011822205 0.08971702 9 85575315 85575475 161 - 0.986 1.192 0.745
ENSG00000135049 E007 11.6946362 0.001352834 0.075606015 0.28089377 9 85578920 85579096 177 - 1.026 1.170 0.519
ENSG00000135049 E008 11.1097158 0.004843500 0.751073394 0.90179419 9 85585463 85585594 132 - 1.097 1.069 -0.101
ENSG00000135049 E009 12.3435799 0.037619931 0.910345790 0.97163362 9 85586831 85586960 130 - 1.120 1.131 0.037
ENSG00000135049 E010 11.0316221 0.001493498 0.529867532 0.78121773 9 85588298 85588478 181 - 1.054 1.105 0.186
ENSG00000135049 E011 9.7982298 0.001899325 0.870371766 0.95532237 9 85589528 85589681 154 - 1.026 1.040 0.050
ENSG00000135049 E012 10.9031815 0.011943888 0.781979504 0.91614078 9 85592560 85592704 145 - 1.063 1.088 0.089
ENSG00000135049 E013 7.6329213 0.007769676 0.188500894 0.46688745 9 85596362 85596449 88 - 0.865 0.997 0.496
ENSG00000135049 E014 8.4632633 0.008799922 0.634013963 0.84358972 9 85618983 85619131 149 - 0.953 0.997 0.163
ENSG00000135049 E015 6.9316456 0.020889785 0.223965929 0.51157794 9 85619215 85619301 87 - 0.965 0.821 -0.549
ENSG00000135049 E016 6.7183568 0.002354997 0.722792781 0.88860331 9 85621202 85621285 84 - 0.905 0.868 -0.141
ENSG00000135049 E017 12.6902708 0.025035209 0.791115212 0.91993774 9 85632662 85633037 376 - 1.150 1.122 -0.100
ENSG00000135049 E018 4.6076825 0.005304354 0.176605998 0.45086945 9 85633038 85633136 99 - 0.822 0.660 -0.656
ENSG00000135049 E019 9.6159668 0.001705761 0.274886524 0.56838406 9 85633137 85633374 238 - 1.072 0.974 -0.357
ENSG00000135049 E020 5.7790937 0.016047759 0.002480354 0.02992738 9 85642827 85642943 117 - 0.975 0.609 -1.463
ENSG00000135049 E021 5.2466921 0.007861395 0.643922040 0.84916845 9 85646321 85646418 98 - 0.822 0.767 -0.215
ENSG00000135049 E022 3.5134566 0.004182145 0.148609984 0.41061121 9 85655143 85655200 58 - 0.737 0.551 -0.804
ENSG00000135049 E023 2.2872590 0.024547298 0.066255872 0.25918939 9 85655201 85655215 15 - 0.632 0.357 -1.364
ENSG00000135049 E024 3.5393616 0.004880963 0.748168410 0.90062751 9 85655216 85655320 105 - 0.677 0.635 -0.178
ENSG00000135049 E025 1.6230969 0.009040502 0.033527153 0.17425590 9 85657435 85657437 3 - 0.231 0.551 1.859
ENSG00000135049 E026 1.7496039 0.015564401 0.020607230 0.12933114 9 85657438 85657453 16 - 0.231 0.581 1.996
ENSG00000135049 E027 5.6263422 0.003098374 0.998216208 1.00000000 9 85657454 85657643 190 - 0.822 0.821 -0.004
ENSG00000135049 E028 2.8278004 0.037229571 0.437598308 0.71387517 9 85660936 85660973 38 - 0.525 0.635 0.501
ENSG00000135049 E029 4.0182184 0.009488785 0.548723588 0.79362152 9 85669485 85669578 94 - 0.737 0.660 -0.319
ENSG00000135049 E030 4.9794932 0.003321587 0.259266221 0.55182125 9 85672550 85672681 132 - 0.837 0.706 -0.522
ENSG00000135049 E031 5.0190099 0.002942427 0.905042197 0.96954500 9 85677436 85677582 147 - 0.773 0.786 0.051
ENSG00000135049 E032 3.0382396 0.004810128 0.433488196 0.71091168 9 85678335 85678398 64 - 0.655 0.551 -0.463
ENSG00000135049 E033 3.3978665 0.005107917 0.368921151 0.65737261 9 85681268 85681335 68 - 0.698 0.581 -0.506
ENSG00000135049 E034 4.6845267 0.020771269 0.141646634 0.40048069 9 85692689 85692813 125 - 0.655 0.837 0.739
ENSG00000135049 E035 2.0656521 0.012734185 0.588646834 0.81751375 9 85712502 85712566 65 - 0.525 0.445 -0.393
ENSG00000135049 E036 2.1519581 0.059141980 0.012288483 0.09185427 9 85741775 85742029 255 - 0.655 0.247 -2.200

Help

Please Click HERE to learn more details about the results from DEXseq.