ENSG00000135108

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000330622 ENSG00000135108 No_inf pgKDN_inf FBXO21 protein_coding protein_coding 6.822917 4.882669 8.959684 0.1890025 0.1034584 0.8744355 1.696437 0.1484187 3.420611 0.1484187 0.3523033 4.4366507 0.207100 0.033050 0.380625 0.347575 0.006084436 0.006084436 FALSE TRUE
ENST00000622495 ENSG00000135108 No_inf pgKDN_inf FBXO21 protein_coding protein_coding 6.822917 4.882669 8.959684 0.1890025 0.1034584 0.8744355 5.043245 4.4845462 5.539073 0.2000078 0.2563707 0.3040713 0.776875 0.918875 0.619375 -0.299500 0.015450093 0.006084436 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135108 E001 78.3797266 0.0002985169 3.667286e-06 0.0001435351 12 117141991 117145048 3058 - 1.839 1.960 0.408
ENSG00000135108 E002 3.5124953 0.0627133079 4.999486e-01 0.7601766319 12 117145049 117145067 19 - 0.700 0.584 -0.500
ENSG00000135108 E003 46.6242875 0.0005548558 1.626850e-03 0.0217777440 12 117145068 117146277 1210 - 1.729 1.598 -0.446
ENSG00000135108 E004 0.0000000       12 117154250 117154302 53 -      
ENSG00000135108 E005 0.4991656 0.0228126592 1.956587e-01   12 117155054 117155615 562 - 0.083 0.267 2.007
ENSG00000135108 E006 8.9181979 0.0019331993 4.721616e-01 0.7394826754 12 117155791 117155948 158 - 0.965 1.027 0.228
ENSG00000135108 E007 10.1927687 0.0014153754 2.985583e-01 0.5916081698 12 117157873 117158063 191 - 1.086 0.991 -0.347
ENSG00000135108 E008 1.3252357 0.0101313713 3.029128e-01 0.5960458637 12 117158064 117158084 21 - 0.430 0.267 -0.989
ENSG00000135108 E009 8.2048105 0.0028426114 2.604636e-01 0.5530746549 12 117165485 117165617 133 - 0.913 1.016 0.383
ENSG00000135108 E010 9.2934014 0.0015747721 3.798816e-01 0.6664938009 12 117166898 117167077 180 - 0.975 1.050 0.274
ENSG00000135108 E011 2.8407066 0.0058520392 7.861134e-02 0.2873295573 12 117172471 117172509 39 - 0.462 0.697 1.064
ENSG00000135108 E012 4.4397988 0.0039513528 2.510925e-02 0.1457300472 12 117172510 117172607 98 - 0.597 0.860 1.079
ENSG00000135108 E013 5.4287432 0.0114559979 1.376304e-01 0.3949643108 12 117174205 117174341 137 - 0.878 0.697 -0.720
ENSG00000135108 E014 1.9121408 0.0150171276 4.895101e-02 0.2180643243 12 117174651 117174654 4 - 0.573 0.267 -1.689
ENSG00000135108 E015 6.5345451 0.0422293837 2.527505e-01 0.5441179607 12 117174655 117174797 143 - 0.935 0.786 -0.573
ENSG00000135108 E016 5.8271678 0.0026828565 4.891620e-01 0.7521300400 12 117177520 117177641 122 - 0.865 0.786 -0.311
ENSG00000135108 E017 4.9487303 0.0366816447 1.368668e-01 0.3937662048 12 117186477 117186571 95 - 0.853 0.644 -0.847
ENSG00000135108 E018 0.0000000       12 117188759 117188793 35 -      
ENSG00000135108 E019 0.0000000       12 117188794 117189226 433 -      
ENSG00000135108 E020 6.4980760 0.0464388615 4.542965e-02 0.2084746449 12 117189227 117189362 136 - 0.975 0.697 -1.088
ENSG00000135108 E021 3.9791597 0.0179547374 1.778497e-01 0.4526304215 12 117190218 117190480 263 - 0.768 0.584 -0.775

Help

Please Click HERE to learn more details about the results from DEXseq.