ENSG00000135185

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000257637 ENSG00000135185 No_inf pgKDN_inf TMEM243 protein_coding protein_coding 17.68998 17.77533 20.10597 1.138825 0.6704657 0.1776541 7.9907087 10.055943 11.906330 1.2079679 0.6694261 0.24345770 0.42704167 0.560150 0.593750 0.033600 9.108938e-01 6.119859e-05 FALSE FALSE
ENST00000423734 ENSG00000135185 No_inf pgKDN_inf TMEM243 protein_coding protein_coding 17.68998 17.77533 20.10597 1.138825 0.6704657 0.1776541 0.9680218 2.659179 0.000000 0.7866272 0.0000000 -8.06025216 0.05434167 0.147600 0.000000 -0.147600 6.119859e-05 6.119859e-05 FALSE TRUE
ENST00000433078 ENSG00000135185 No_inf pgKDN_inf TMEM243 protein_coding protein_coding 17.68998 17.77533 20.10597 1.138825 0.6704657 0.1776541 6.1511460 1.721279 5.716326 1.1510306 0.4931041 1.72577110 0.37581667 0.110100 0.283675 0.173575 3.630774e-01 6.119859e-05 TRUE FALSE
ENST00000455575 ENSG00000135185 No_inf pgKDN_inf TMEM243 protein_coding protein_coding 17.68998 17.77533 20.10597 1.138825 0.6704657 0.1776541 1.3157077 1.450281 1.499298 0.7582709 0.5596167 0.04763221 0.07150833 0.076725 0.074650 -0.002075 9.828982e-01 6.119859e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135185 E001 0.0000000       7 87196160 87196161 2 -      
ENSG00000135185 E002 19.9795259 0.0007969622 0.2587716811 0.551229979 7 87196162 87196599 438 - 1.287 1.355 0.238
ENSG00000135185 E003 20.2605342 0.0008450758 0.7583672659 0.905143653 7 87196600 87196758 159 - 1.336 1.319 -0.059
ENSG00000135185 E004 0.1170040 0.0117881645 0.6082198178   7 87197701 87197717 17 - 0.090 0.000 -9.479
ENSG00000135185 E005 1.6411643 0.0094066144 0.0004779919 0.008427595 7 87197718 87197940 223 - 0.090 0.616 3.770
ENSG00000135185 E006 13.1629604 0.0015818286 0.4635021548 0.733331140 7 87197941 87197982 42 - 1.176 1.123 -0.191
ENSG00000135185 E007 14.5536528 0.0012976154 0.8140435736 0.932038936 7 87197983 87198045 63 - 1.183 1.201 0.064
ENSG00000135185 E008 0.8644943 0.0137900057 0.5882105828 0.817221782 7 87198228 87199006 779 - 0.228 0.310 0.600
ENSG00000135185 E009 9.1759798 0.0017499186 0.8407949142 0.942909111 7 87199007 87199057 51 - 0.998 1.017 0.070
ENSG00000135185 E010 1.9615461 0.0096139712 0.8053760950 0.927920196 7 87199058 87199613 556 - 0.453 0.490 0.185
ENSG00000135185 E011 0.3703650 0.0170773972 0.5083270555   7 87202964 87203043 80 - 0.090 0.182 1.185
ENSG00000135185 E012 0.2537694 0.0165876652 0.2020856313   7 87216740 87216921 182 - 0.000 0.182 10.744
ENSG00000135185 E013 7.8114831 0.0678318542 0.8429142221 0.943771106 7 87219426 87219488 63 - 0.956 0.933 -0.087
ENSG00000135185 E014 13.7845795 0.0016308545 0.4318128188 0.709398306 7 87219489 87219718 230 - 1.196 1.140 -0.200
ENSG00000135185 E015 0.8616590 0.0130892786 0.5889448358 0.817752379 7 87219719 87219732 14 - 0.228 0.310 0.600
ENSG00000135185 E016 1.4537580 0.0119376105 0.3448051936 0.635937603 7 87220217 87220360 144 - 0.453 0.310 -0.815
ENSG00000135185 E017 3.2451151 0.0510564679 0.0451660268 0.207793931 7 87220361 87220587 227 - 0.747 0.451 -1.330

Help

Please Click HERE to learn more details about the results from DEXseq.