ENSG00000135341

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369329 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding protein_coding 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 3.156414 1.221476 3.761635 1.2214764 1.8063465 1.614801 0.06661667 0.028150 0.073250 0.045100 0.45205027 0.01714616 FALSE  
ENST00000369332 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding protein_coding 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 8.901442 16.444750 7.535338 1.8939712 3.1258524 -1.124847 0.19803333 0.387600 0.144125 -0.243475 0.34174411 0.01714616 FALSE  
ENST00000479630 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding protein_coding_CDS_not_defined 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 3.075287 3.972822 1.789171 0.2947109 0.2728339 -1.146459 0.06852500 0.093325 0.034825 -0.058500 0.18519786 0.01714616 FALSE  
ENST00000700583 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding nonsense_mediated_decay 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 8.713463 3.761507 12.453071 1.8263274 2.5665497 1.724446 0.18367500 0.087700 0.242275 0.154575 0.37930954 0.01714616 FALSE  
ENST00000700585 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding nonsense_mediated_decay 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 1.308132 3.924397 0.000000 1.3454517 0.0000000 -8.619999 0.03095000 0.092850 0.000000 -0.092850 0.01714616 0.01714616 FALSE  
ENST00000700593 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding protein_coding 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 11.800442 6.967459 15.944432 3.0778690 3.9889572 1.193184 0.24884167 0.162800 0.305275 0.142475 0.67044425 0.01714616 FALSE  
ENST00000703101 ENSG00000135341 No_inf pgKDN_inf MAP3K7 protein_coding protein_coding 46.46154 42.51061 51.99211 0.4687668 1.43658 0.2904077 1.323060 0.000000 3.553792 0.0000000 2.6013837 8.477269 0.02454167 0.000000 0.064900 0.064900 0.50354330 0.01714616 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135341 E001 0.2459655 0.0161218717 9.921012e-01   6 90513573 90513578 6 - 0.095 0.096 0.017
ENSG00000135341 E002 0.9819040 0.0923822932 9.988920e-01 1.000000e+00 6 90513579 90513600 22 - 0.295 0.298 0.017
ENSG00000135341 E003 2.8517546 0.0138296343 1.480620e-01 4.097058e-01 6 90513601 90513637 37 - 0.469 0.671 0.924
ENSG00000135341 E004 16.4583879 0.0257552480 1.922129e-02 1.238272e-01 6 90513638 90513818 181 - 1.112 1.336 0.794
ENSG00000135341 E005 114.8464912 0.0001600193 1.942650e-17 4.141300e-15 6 90513819 90515040 1222 - 1.927 2.162 0.790
ENSG00000135341 E006 9.7657374 0.0014396139 1.603888e-02 1.098185e-01 6 90515041 90515092 52 - 0.906 1.124 0.803
ENSG00000135341 E007 25.6340072 0.0005461456 9.729686e-03 7.888769e-02 6 90515093 90515377 285 - 1.341 1.492 0.522
ENSG00000135341 E008 27.4878002 0.0005404396 3.048201e-01 5.980835e-01 6 90515378 90515633 256 - 1.424 1.481 0.198
ENSG00000135341 E009 5.5875070 0.0052498089 1.617749e-01 4.300443e-01 6 90515634 90515648 15 - 0.893 0.735 -0.620
ENSG00000135341 E010 6.8230024 0.0064056685 3.265285e-01 6.189440e-01 6 90515649 90515661 13 - 0.944 0.839 -0.398
ENSG00000135341 E011 5.1293516 0.0169204091 5.946418e-01 8.217622e-01 6 90515662 90515667 6 - 0.819 0.754 -0.259
ENSG00000135341 E012 5.8727507 0.0025994965 8.086535e-01 9.293597e-01 6 90515668 90515682 15 - 0.850 0.824 -0.103
ENSG00000135341 E013 10.7576456 0.0013122582 5.647559e-01 8.039209e-01 6 90515683 90515736 54 - 1.095 1.045 -0.180
ENSG00000135341 E014 7.9304622 0.0021628952 4.190358e-01 6.987592e-01 6 90515737 90515741 5 - 0.989 0.911 -0.295
ENSG00000135341 E015 9.5276867 0.0025123021 5.398983e-01 7.881447e-01 6 90515742 90515757 16 - 1.050 0.994 -0.205
ENSG00000135341 E016 18.9587731 0.0008034804 7.471335e-01 9.001532e-01 6 90515758 90515815 58 - 1.311 1.289 -0.076
ENSG00000135341 E017 15.8118377 0.0008638782 7.394252e-01 8.967545e-01 6 90515816 90515827 12 - 1.213 1.237 0.084
ENSG00000135341 E018 15.9211937 0.0008544948 9.438933e-01 9.844702e-01 6 90515828 90515837 10 - 1.226 1.231 0.017
ENSG00000135341 E019 31.4969542 0.0004459150 6.807881e-01 8.681671e-01 6 90515838 90515907 70 - 1.500 1.522 0.073
ENSG00000135341 E020 231.1425469 0.0001312972 9.533263e-01 9.885480e-01 6 90515908 90516681 774 - 2.366 2.365 -0.004
ENSG00000135341 E021 51.7930532 0.0056135828 2.806305e-01 5.739317e-01 6 90518447 90518562 116 - 1.750 1.695 -0.187
ENSG00000135341 E022 36.8796283 0.0003875859 2.015400e-01 4.839436e-01 6 90519258 90519319 62 - 1.609 1.547 -0.213
ENSG00000135341 E023 39.3157718 0.0003497720 8.666168e-01 9.540355e-01 6 90523678 90523783 106 - 1.601 1.609 0.026
ENSG00000135341 E024 29.9221712 0.0004559470 2.639940e-01 5.571206e-01 6 90536337 90536401 65 - 1.520 1.460 -0.207
ENSG00000135341 E025 11.4153060 0.0012528932 3.014609e-04 5.829685e-03 6 90536402 90537218 817 - 0.906 1.218 1.136
ENSG00000135341 E026 2.0069331 0.0150183827 1.063313e-02 8.361092e-02 6 90537333 90537410 78 - 0.238 0.623 2.132
ENSG00000135341 E027 0.9895583 0.0543773882 4.891077e-01 7.521300e-01 6 90542460 90542529 70 - 0.238 0.349 0.754
ENSG00000135341 E028 5.5203811 0.0031479666 6.303128e-01 8.414470e-01 6 90544552 90544632 81 - 0.786 0.839 0.210
ENSG00000135341 E029 3.4312336 0.0046429972 9.739566e-01 9.953877e-01 6 90545218 90546282 1065 - 0.644 0.648 0.017
ENSG00000135341 E030 42.6886201 0.0003465938 4.201355e-02 1.994331e-01 6 90547258 90547387 130 - 1.685 1.593 -0.314
ENSG00000135341 E031 0.0000000       6 90547388 90547450 63 -      
ENSG00000135341 E032 44.3568051 0.0003320267 2.100892e-02 1.308877e-01 6 90548047 90548177 131 - 1.707 1.604 -0.350
ENSG00000135341 E033 35.7022769 0.0004010870 5.505795e-01 7.948458e-01 6 90550468 90550549 82 - 1.580 1.550 -0.102
ENSG00000135341 E034 0.7357239 0.0142850890 9.880475e-01 9.998901e-01 6 90550550 90550726 177 - 0.238 0.240 0.017
ENSG00000135341 E035 0.7459172 0.3808765373 5.354951e-01 7.852472e-01 6 90550727 90550785 59 - 0.172 0.298 1.016
ENSG00000135341 E036 8.8046058 0.0017190001 2.541818e-03 3.049164e-02 6 90550786 90552048 1263 - 0.819 1.108 1.078
ENSG00000135341 E037 41.6390079 0.0003713156 8.230160e-01 9.356578e-01 6 90552049 90552179 131 - 1.625 1.635 0.034
ENSG00000135341 E038 0.0000000       6 90552979 90553168 190 -      
ENSG00000135341 E039 41.5215818 0.0003579902 7.750950e-03 6.766330e-02 6 90553458 90553582 125 - 1.687 1.565 -0.418
ENSG00000135341 E040 14.6037130 0.0084888469 1.581629e-01 4.250090e-01 6 90553583 90553586 4 - 1.250 1.132 -0.419
ENSG00000135341 E041 33.2049075 0.0042872534 2.668773e-01 5.601987e-01 6 90556500 90556624 125 - 1.565 1.502 -0.217
ENSG00000135341 E042 34.7588210 0.0048429313 1.223714e-01 3.700993e-01 6 90560076 90560214 139 - 1.596 1.509 -0.298
ENSG00000135341 E043 3.1824925 0.1683925740 8.735508e-01 9.569172e-01 6 90560215 90560234 20 - 0.620 0.623 0.015
ENSG00000135341 E044 0.3617683 0.1648017323 6.251376e-01   6 90560396 90560673 278 - 0.172 0.096 -0.983
ENSG00000135341 E045 22.3410078 0.0009038933 1.907674e-01 4.700365e-01 6 90561622 90561667 46 - 1.408 1.326 -0.284
ENSG00000135341 E046 0.2346346 0.0159621448 2.466210e-01   6 90568164 90568200 37 - 0.172 0.000 -9.587
ENSG00000135341 E047 25.2803669 0.0024257810 2.397026e-01 5.287294e-01 6 90568558 90568623 66 - 1.455 1.383 -0.249
ENSG00000135341 E048 28.5336049 0.0004936962 6.208401e-02 2.502757e-01 6 90571697 90571807 111 - 1.520 1.417 -0.355
ENSG00000135341 E049 0.2455571 0.0162394283 9.923780e-01   6 90578988 90579125 138 - 0.095 0.096 0.017
ENSG00000135341 E050 0.0000000       6 90585655 90585716 62 -      
ENSG00000135341 E051 0.7349337 0.0143454731 9.879847e-01 9.998901e-01 6 90586466 90586688 223 - 0.238 0.240 0.017
ENSG00000135341 E052 0.3707734 0.0167756593 5.758711e-01   6 90586689 90586763 75 - 0.095 0.174 1.017
ENSG00000135341 E053 15.2428070 0.0043117422 1.708129e-01 4.430850e-01 6 90586764 90586837 74 - 1.262 1.155 -0.378
ENSG00000135341 E054 22.7687275 0.0016416919 2.481860e-05 7.419992e-04 6 90586838 90587086 249 - 1.494 1.224 -0.937

Help

Please Click HERE to learn more details about the results from DEXseq.