ENSG00000135363

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000395833 ENSG00000135363 No_inf pgKDN_inf LMO2 protein_coding protein_coding 60.31263 133.3247 29.83291 2.616179 0.6914817 -2.159592 35.227999 73.121428 19.7138393 2.466753 0.7577686 -1.8905511 0.64230833 0.549875 0.663275 0.113400 0.3755780721 0.0004434844 FALSE TRUE
ENST00000464025 ENSG00000135363 No_inf pgKDN_inf LMO2 protein_coding retained_intron 60.31263 133.3247 29.83291 2.616179 0.6914817 -2.159592 6.325644 17.237695 0.1651400 4.427372 0.1651400 -6.6217509 0.07488333 0.127525 0.005775 -0.121750 0.0004434844 0.0004434844 FALSE TRUE
MSTRG.4590.14 ENSG00000135363 No_inf pgKDN_inf LMO2 protein_coding   60.31263 133.3247 29.83291 2.616179 0.6914817 -2.159592 1.992290 1.542931 3.4614028 1.542931 1.0719187 1.1605246 0.06135000 0.011025 0.114350 0.103325 0.0176072667 0.0004434844 FALSE TRUE
MSTRG.4590.2 ENSG00000135363 No_inf pgKDN_inf LMO2 protein_coding   60.31263 133.3247 29.83291 2.616179 0.6914817 -2.159592 2.897684 8.319559 0.2045278 1.482873 0.2045278 -5.2790036 0.02604167 0.062925 0.006425 -0.056500 0.0291679278 0.0004434844 FALSE TRUE
MSTRG.4590.6 ENSG00000135363 No_inf pgKDN_inf LMO2 protein_coding   60.31263 133.3247 29.83291 2.616179 0.6914817 -2.159592 3.024632 4.919089 3.2326865 1.641058 1.1016366 -0.6041316 0.06650833 0.036375 0.107350 0.070975 0.7964713142 0.0004434844 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135363 E001 0.5073513 1.585264e-02 0.744159128 0.89873493 11 33858576 33858577 2 - 0.000 0.159 8.928
ENSG00000135363 E002 0.8804531 1.242836e-02 0.960579207 0.99117793 11 33858578 33858578 1 - 0.188 0.221 0.297
ENSG00000135363 E003 497.2221035 8.220757e-05 0.001737682 0.02289082 11 33858579 33859575 997 - 2.529 2.569 0.134
ENSG00000135363 E004 82.3030636 2.151818e-04 0.207093699 0.49068057 11 33864602 33864763 162 - 1.830 1.779 -0.170
ENSG00000135363 E005 42.5165118 3.622226e-04 0.039025007 0.19128249 11 33864764 33864817 54 - 1.601 1.487 -0.392
ENSG00000135363 E006 2.6385885 5.550280e-03 0.742776608 0.89832747 11 33864818 33864929 112 - 0.419 0.476 0.297
ENSG00000135363 E007 4.6715142 1.020071e-02 0.125362980 0.37533490 11 33864930 33865151 222 - 0.419 0.678 1.214
ENSG00000135363 E008 77.5853905 2.059557e-04 0.037664182 0.18720671 11 33869346 33869544 199 - 1.833 1.748 -0.288
ENSG00000135363 E009 32.9883704 3.509517e-03 0.030056674 0.16313142 11 33869545 33869586 42 - 1.517 1.375 -0.491
ENSG00000135363 E010 17.3054462 7.065803e-03 0.003979304 0.04227296 11 33869587 33869709 123 - 1.334 1.086 -0.878
ENSG00000135363 E011 15.8939846 1.005499e-03 0.299632791 0.59249844 11 33869710 33869824 115 - 1.178 1.086 -0.330
ENSG00000135363 E012 21.7899367 6.361308e-04 0.478888960 0.74480642 11 33869825 33869987 163 - 1.275 1.221 -0.193
ENSG00000135363 E013 2.7911519 1.124677e-02 0.010461592 0.08269610 11 33870140 33870344 205 - 0.000 0.536 12.584
ENSG00000135363 E014 5.4488117 2.578885e-03 0.002010072 0.02565085 11 33870345 33870699 355 - 0.188 0.752 3.104
ENSG00000135363 E015 1.7681422 7.829942e-03 0.290462609 0.58404205 11 33877764 33877790 27 - 0.188 0.387 1.412
ENSG00000135363 E016 2.5298921 5.549875e-03 0.107131380 0.34300600 11 33877791 33877864 74 - 0.188 0.492 1.960
ENSG00000135363 E017 0.4993265 1.570502e-02 0.638234032   11 33881819 33881823 5 - 0.188 0.125 -0.703
ENSG00000135363 E018 8.7228285 1.594674e-03 0.005368578 0.05215218 11 33881824 33881887 64 - 0.500 0.914 1.734
ENSG00000135363 E019 0.4996088 1.572338e-02 0.638345237   11 33881888 33881890 3 - 0.188 0.125 -0.703
ENSG00000135363 E020 5.1386111 2.217826e-02 0.972583673 0.99486644 11 33891090 33891322 233 - 0.680 0.678 -0.008
ENSG00000135363 E021 11.1182438 2.775113e-03 0.005219984 0.05121604 11 33891795 33892142 348 - 0.628 1.004 1.484

Help

Please Click HERE to learn more details about the results from DEXseq.