ENSG00000135387

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341394 ENSG00000135387 No_inf pgKDN_inf CAPRIN1 protein_coding protein_coding 80.1858 72.90453 92.21655 1.25742 1.502772 0.3389759 51.191883 36.604804 61.625623 3.0417270 3.0813302 0.7513373 0.63449167 0.502875 0.667275 0.164400 0.095539571 0.008663685 FALSE TRUE
ENST00000530820 ENSG00000135387 No_inf pgKDN_inf CAPRIN1 protein_coding protein_coding 80.1858 72.90453 92.21655 1.25742 1.502772 0.3389759 8.190907 8.387388 8.612298 0.1115937 0.6887768 0.0381317 0.10303333 0.115200 0.093425 -0.021775 0.828182219 0.008663685 FALSE TRUE
ENST00000531668 ENSG00000135387 No_inf pgKDN_inf CAPRIN1 protein_coding protein_coding_CDS_not_defined 80.1858 72.90453 92.21655 1.25742 1.502772 0.3389759 2.975979 8.927938 0.000000 4.1212851 0.0000000 -9.8037982 0.04030833 0.120925 0.000000 -0.120925 0.008663685 0.008663685 FALSE FALSE
ENST00000532820 ENSG00000135387 No_inf pgKDN_inf CAPRIN1 protein_coding protein_coding 80.1858 72.90453 92.21655 1.25742 1.502772 0.3389759 9.424969 3.177546 13.963962 0.6349861 3.6405117 2.1322230 0.11471667 0.043275 0.153100 0.109825 0.089373075 0.008663685 FALSE TRUE
ENST00000533657 ENSG00000135387 No_inf pgKDN_inf CAPRIN1 protein_coding protein_coding_CDS_not_defined 80.1858 72.90453 92.21655 1.25742 1.502772 0.3389759 5.122807 10.179871 5.188549 3.9232648 1.9891376 -0.9709548 0.06532500 0.140575 0.055400 -0.085175 0.833089495 0.008663685 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135387 E001 2.6735448 0.0052416884 7.139982e-01 0.884852450 11 34051731 34051731 1 + 0.584 0.540 -0.202
ENSG00000135387 E002 3.8791646 0.0036483542 4.070131e-01 0.689581275 11 34051732 34051750 19 + 0.730 0.633 -0.409
ENSG00000135387 E003 15.2877627 0.0033749435 1.025394e-01 0.334787965 11 34051751 34051871 121 + 1.261 1.143 -0.421
ENSG00000135387 E004 0.1176306 0.0117423966 6.603320e-01   11 34052055 34052162 108 + 0.086 0.000 -12.388
ENSG00000135387 E005 1.5870261 0.0089796543 9.246619e-01 0.977150746 11 34052210 34052328 119 + 0.403 0.423 0.106
ENSG00000135387 E006 8.8267572 0.0038923447 4.347050e-02 0.203395326 11 34052329 34052420 92 + 1.068 0.880 -0.701
ENSG00000135387 E007 53.6717203 0.0015412790 7.799615e-05 0.001931425 11 34052421 34052636 216 + 1.806 1.639 -0.565
ENSG00000135387 E008 0.3634051 0.0165045357 7.196003e-01   11 34052637 34052867 231 + 0.157 0.105 -0.672
ENSG00000135387 E009 0.4998907 0.0156620033 2.299236e-01 0.518402224 11 34052981 34053185 205 + 0.086 0.261 1.913
ENSG00000135387 E010 0.2542726 0.2512306105 2.288249e-01   11 34053451 34053519 69 + 0.000 0.190 12.043
ENSG00000135387 E011 0.2542726 0.2512306105 2.288249e-01   11 34053522 34053671 150 + 0.000 0.190 12.043
ENSG00000135387 E012 0.2362687 0.0156751028 3.216125e-01   11 34055686 34055737 52 + 0.157 0.000 -13.303
ENSG00000135387 E013 0.1186381 0.0118008294 6.602735e-01   11 34055738 34055740 3 + 0.086 0.000 -12.387
ENSG00000135387 E014 0.4997647 0.0261120199 2.324852e-01   11 34055741 34055805 65 + 0.086 0.261 1.913
ENSG00000135387 E015 0.6168623 0.3578538871 7.041213e-01 0.879691410 11 34056486 34056571 86 + 0.158 0.261 0.911
ENSG00000135387 E016 0.3728195 0.0166212506 4.632938e-01   11 34063052 34063363 312 + 0.086 0.190 1.328
ENSG00000135387 E017 38.1579169 0.0003753771 4.384133e-02 0.204491768 11 34071726 34071788 63 + 1.631 1.541 -0.307
ENSG00000135387 E018 46.6173489 0.0004318465 1.010531e-02 0.080847693 11 34071901 34071987 87 + 1.722 1.616 -0.361
ENSG00000135387 E019 107.6381819 0.0001526106 9.692175e-06 0.000331266 11 34076236 34076474 239 + 2.086 1.965 -0.406
ENSG00000135387 E020 56.9517651 0.0003147343 9.820478e-02 0.326868464 11 34076560 34076642 83 + 1.787 1.730 -0.195
ENSG00000135387 E021 70.5809972 0.0016175728 1.064723e-01 0.341692038 11 34079628 34079765 138 + 1.878 1.823 -0.184
ENSG00000135387 E022 43.6579968 0.0017899956 8.052659e-01 0.927903674 11 34082825 34082877 53 + 1.650 1.647 -0.012
ENSG00000135387 E023 55.8607840 0.0028354534 8.507975e-01 0.947214621 11 34082955 34083041 87 + 1.754 1.753 -0.001
ENSG00000135387 E024 89.2201036 0.0001766565 6.965708e-01 0.876096032 11 34086064 34086219 156 + 1.944 1.965 0.071
ENSG00000135387 E025 72.2255856 0.0002913853 2.206676e-01 0.507603368 11 34086305 34086413 109 + 1.879 1.844 -0.118
ENSG00000135387 E026 50.1490619 0.0002836277 9.437761e-01 0.984427032 11 34089395 34089456 62 + 1.702 1.714 0.040
ENSG00000135387 E027 0.3729758 0.2169632597 5.161828e-01   11 34090026 34090178 153 + 0.086 0.190 1.328
ENSG00000135387 E028 81.8594883 0.0012465363 8.185054e-01 0.933939748 11 34090179 34090289 111 + 1.909 1.926 0.057
ENSG00000135387 E029 104.0689568 0.0031021011 9.827735e-01 0.998690264 11 34090529 34090678 150 + 2.016 2.025 0.033
ENSG00000135387 E030 0.1268540 0.0122960288 4.366589e-01   11 34091619 34091905 287 + 0.000 0.105 11.999
ENSG00000135387 E031 102.5471552 0.0001774465 1.737807e-01 0.447242010 11 34091906 34092056 151 + 2.028 1.996 -0.107
ENSG00000135387 E032 0.2543986 0.0159960673 1.794080e-01   11 34095819 34095851 33 + 0.000 0.190 12.928
ENSG00000135387 E033 1.7321089 0.0078566010 1.489932e-01 0.411206480 11 34096160 34096478 319 + 0.321 0.540 1.176
ENSG00000135387 E034 105.0389241 0.0011432957 3.984477e-01 0.682348255 11 34096479 34096629 151 + 2.033 2.014 -0.062
ENSG00000135387 E035 68.8118206 0.0002345505 9.924061e-01 1.000000000 11 34096630 34096673 44 + 1.838 1.848 0.031
ENSG00000135387 E036 119.0581359 0.0002025232 5.265492e-01 0.778842990 11 34097196 34097296 101 + 2.066 2.092 0.088
ENSG00000135387 E037 95.9374371 0.0008523751 2.756248e-01 0.569255870 11 34097698 34097761 64 + 1.964 2.008 0.148
ENSG00000135387 E038 47.7426796 0.0003099926 6.898512e-04 0.011225572 11 34097762 34099058 1297 + 1.608 1.764 0.529
ENSG00000135387 E039 1153.3974283 0.0007732058 2.802436e-04 0.005494242 11 34099303 34102610 3308 + 3.041 3.084 0.144

Help

Please Click HERE to learn more details about the results from DEXseq.